Results 251 to 260 of about 43,955 (304)

Dysregulated lipid metabolism in kidney stone pathogenesis: a literature review of mechanistic insights and therapeutic implications. [PDF]

BMC Urol
Wen Q, Li Q, Zhou H, Su B, Ren Y, He Q.
europepmc   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Apolipoprotein and menopausal status are significant influencing factors for diabetic retinopathy in type II diabetes mellitus women. [PDF]

Sci Rep
Pei X, Yao X, Qi D, Yang Y, Fan S, Li Z.
europepmc   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Evinacumab Improved the Homozygous Familial Hypercholesterolemia Lipid Metabolism: A Case Report. [PDF]

J Atheroscler Thromb
Matsuda T, Osaki Y, Matsumoto N, Nakajima R, Murayama Y, Sugano Y, Iwasaki H, Mathis BJ, Sekiya M, Shimano H.   +9 more
europepmc   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Insight into the metabolic shifts in Graves' hyperthyroidism: a study of acylcarnitine and lipid profiles. [PDF]

Eur Thyroid J
Neset MT, Ulvik A, Løvås K, Laupsa-Borge J, Breivik LE, Stokland AM, Nedrebø BG, Rødahl E, Husebye E, Ueland GÅ, Ueland HO.   +10 more
europepmc   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

Impact of Graves' hyperthyroidism treatment on lipid profiles and cholesterol dynamics: a prospective observational study. [PDF]

Ther Adv Endocrinol Metab
Nagamine T, Tanimura-Inagaki K, Nagao M, Kobayashi S, Shuto Y, Tamura H, Okazaki-Hada M, Fukuda I, Sugihara H, Oikawa S, Iwabu M.   +10 more
europepmc   +1 more source

The Longitudinal Effect of APOL1 Risk Alleles on Sickle Cell Anemia‐Associated Kidney Function

American Journal of Hematology, Volume 101, Issue 6, Page 1341-1350, June 2026.
ABSTRACT Progressive kidney injury is a major cause of morbidity and mortality in sickle cell anemia (SCA). The high risk APOL1 G1/G2 variants contribute to the development of kidney disease in individuals of African ancestry, including those with SCA.
Sara R. Rashkin, Guolian Kang, Clifford M. Takemoto, Mitchell J. Weiss, Kenneth I. Ataga, Santosh L. Saraf, Jeffrey Lebensburger, Rima S. Zahr   +7 more
wiley   +1 more source