Results 71 to 80 of about 43,955 (304)

Novel Techniques and Their Applications to Health Foods, Agricultural and Medical Biotechnology: Functional Genomics and Basic Epigenetic Controls in Plant and Animal Cells [PDF]

, 2004
Selected applications of novel techniques for analyzing Health Food formulations, as well as for advanced investigations in Agricultural and Medical Biotechnology aimed at defining the multiple connections between functional genomics and epigenomic ...
Baianu, I.C., Lin, H.C., Lozano, P., Prisecaru, V. I.   +3 more
core  

Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]

, 2015
Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K., Caslake, Muriel J., Cooney, Josephine, GHAFOURI, Khloud, Gill, Jason M.R., Wilson, John   +5 more
core   +1 more source

Administration of a PPARα agonist increases serum apolipoprotein A-V levels and the apolipoprotein A-V/apolipoprotein C-III ratio [PDF]

Journal of Lipid Research, 2005
Apolipoprotein A-V (apoA-V) first gained attention as a regulator of triglycerides through transgenic mouse studies. Furthermore, peroxisome proliferator-activated receptor alpha (PPARalpha) agonists such as fenofibrate increase apoA-V mRNA expression. Our group recently developed the first assay to quantitate serum apoA-V levels.
Albert E. Schultze, William E. Alborn, Ronald K. Newton, Robert J. Konrad   +3 more
openaire   +3 more sources

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

Advanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang, Yundong Li, Xin Wang, Yaning Hou, Wei Deng, Meng Zheng, Yan Zou, Bingyang Shi   +7 more
wiley   +1 more source

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy [PDF]

, 2017
Significance Alzheimer’s disease (AD) is the most common cause of dementia and is a major public health problem for which there is currently no disease-modifying treatment.
Anderson, Elise, Colonna, Marco, Finn, Mary B., Holtzmann, David M., Koscal, Lauren J., Leyns, Cheryl E. G., Robinson, Grace O., Serrano, Javier Remolina, Stewart, Floy R., Ulrich, Jason D.   +9 more
core   +2 more sources

Apolipoprotein A‐V Regulation of Apolipoprotein B Secretion

The FASEB Journal, 2006
Apolipoprotein ( APO ) A5 is a recently discovered member of the APOA1/C3/A4 gene cluster. Studies with APOA5 transgenic and gene disrupted mice showed that apoA‐V is a key regulator of plasma ...
Xiao Shu, Trudy Forte, Robert O. Ryan
openaire   +1 more source

Structure of apolipoprotein C-IIToronto, a nonfunctional human apolipoprotein. [PDF]

Proceedings of the National Academy of Sciences, 1987
We previously reported a family with apolipoprotein C-II (apoC-II) deficiency characterized by the presence of a mutant apoC-II, apoC-IIToronto. We now report the purification and primary structure of apoC-IIToronto. The sequence of apoC-IIToronto is identical to that of normal apoC-II from residues 1-68.
P W, Connelly, G F, Maguire, T, Hofmann, J A, Little   +3 more
openaire   +2 more sources

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36 [PDF]

, 2016
Cluster of differentiation 36 (CD36) variants influence fasting lipids and risk of metabolic syndrome, but their impact on postprandial lipids, an independent risk factor for cardiovascular disease, is unclear. We determined the effects of SNPs within a ~
Abumrad, Nada A, Allum, Fiona, Arnett, Donna K, Aslibekyan, Stella, Borecki, Ingrid B, Deloukas, Panos, Duan, Yanan, Grundberg, Elin, Hedman, Asa K, Hopkins, Paul N, Kraja, Aldi T, Love-Gregory, Latisha, McCarthy, Mark I, Ordovas, Jose M   +13 more
core   +2 more sources

Accumulation of apolipoproteins in the regenerating and remyelinating mammalian peripheral nerve. Identification of apolipoprotein D, apolipoprotein A-IV, apolipoprotein E, and apolipoprotein A-I.

Journal of Biological Chemistry, 1990
In this report, we have identified two apolipoproteins (apo), apoD and apoA-IV, that, together with the previously identified apoA-I and apoE, accumulate in the regenerating peripheral nerve. These four apolipoproteins were identified in regenerating rat sciatic nerves by their molecular weights, their isoelectric points, and their recognition by ...
J K, Boyles, L M, Notterpek, L J, Anderson   +2 more
openaire   +2 more sources