Results 241 to 250 of about 37,488 (288)

Renal Leukocyte Chemotactic Factor 2 (ALECT2) Amyloidosis With Concurrent IgA Nephropathy: A Case Report and Literature Review. [PDF]

Cureus
Gong Q, Gao L, Li H, Zhong R, Huo Y.
europepmc   +1 more source

Why, how and in whom should we measure levels of lipoprotein(a): A review of the latest evidence and clinical implications

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Lipoprotein(a) [Lp(a)] is a genetically determined, causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Despite robust evidence from epidemiological and genetic studies, Lp(a) remains underrecognised in clinical practice due to challenges in measurement, lack of guideline familiarity ...
Alexander C. Razavi, Harpreet S. Bhatia, Roger S. Blumenthal, Michael D. Shapiro, Anurag Mehta   +4 more
wiley   +1 more source

Per- and polyfluoroalkyl substances, apolipoproteins and the risk of coronary heart disease in US men and women. [PDF]

Environ Health
Zhu L, Liu B, Hu Y, Wang M, Furtado JD, Rimm EB, Grandjean P, Sun Q.   +7 more
europepmc   +1 more source

New approach to specific Alzheimer's disease diagnosis based on plasma biomarkers in a cognitive disorder cohort

European Journal of Clinical Investigation, EarlyView.
Abstract Background The validation of a combination of plasma biomarkers and demographic variables is required to establish reliable cut‐offs for Alzheimer's disease diagnosis (AD). Methods Plasma biomarkers (Aβ42/Aβ40, p‐Tau181, t‐Tau, NfL, GFAP), ApoE genotype, and demographic variables were obtained from a retrospective clinical cohort of cognitive ...
Lourdes Álvarez‐Sánchez, Laura Ferré‐González, Carmen Peña‐Bautista, Ángel Balaguer, Julián Luis Amengual, Miguel Baquero, Laura Cubas, Bonaventura Casanova, Consuelo Cháfer‐Pericás   +8 more
wiley   +1 more source

Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen. [PDF]

Invest Ophthalmol Vis Sci
Shaw EM, Anderson DM, Periasamy R, Schey KL, Curcio CA, Lipinski DM.   +5 more
europepmc   +1 more source

Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation

European Journal of Clinical Investigation, EarlyView.
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone, Jean‐Pierre Després, John P. A. Ioannidis, Ian J. Neeland, Gabriella Garruti, Luca Busetto, Luca Liberale, Stefano Ministrini, Gemma Vilahur, Thomas H. Schindler, Maria Paula Macedo, Agostino Di Ciaula, Marcin Krawczyk, Andreas Geier, Gyorgy Baffy, Maria Felicia Faienza, Ilaria Farella, Nicola Santoro, Gema Frühbeck, Patricia Yárnoz‐Esquiroz, Javier Gómez‐Ambrosi, Emma Chávez‐Manzanera, Verónica Vázquez‐Velázquez, Jean‐Michel Oppert, Dimitrios N. Kiortsis, Paolo Sbraccia, Carmine Zoccali, Piero Portincasa, Fabrizio Montecucco   +28 more
wiley   +1 more source

Uncovering host response in adults with severe community-acquired pneumonia: a proteomics and metabolomics perspective study. [PDF]

World J Emerg Med
Kuang Z, Li R, Lu S, Wang Y, Luo Y, Shen Y, Yuan L, Yang Y, Song Z, Jiang N, Tong C.   +10 more
europepmc   +1 more source

Cardioprotective effects of the extracellular chaperone clusterin in acute myocardial infarction

European Journal of Clinical Investigation, EarlyView.
In vivo, CLU−/− mice were more susceptible to acute myocardial infarction than CLU+/+ mice. Moreover, inflammation and histone levels were significantly increased in CLU−/− mice compared to CLU+/+ mice following ischemia/reperfusion. In vitro, CLU protects cardiomyocytes from histone‐ and/or hypoxia‐induced cell death.
Louwana Allawa, Antoine Poirier, Pascale Pignon, Justine Beaumont, Lucie Lebeau, Agnès Barbelivien, Thomas Bochaton, Céline Beauvillain, Daniel Henrion, Yves Delneste, Pascale Jeannin, Fabrice Prunier, Sophie Tamareille   +12 more
wiley   +1 more source

Assessing the causal relationships between circulating metabolic biomarkers and breast cancer by using mendelian randomization. [PDF]

Front Genet
Wang B, Ling Y, Zhang H, Yang M.
europepmc   +1 more source

Concordance‐discordance between apolipoprotein B and lipid biomarkers in predicting 20‐year atherosclerotic cardiovascular disease risk: The ATTICA study (2002–2022)

European Journal of Clinical Investigation, EarlyView.
This study examined the association between 20‐year atherosclerotic cardiovascular disease (ASCVD) risk and discordance among apolipoprotein B100 (apoB) and lipid biomarkers, using established thresholds. ApoB strongly correlated with LDL‐C and non‐HDL‐C, though concordance was limited.
Sofia‐Panagiota Giannakopoulou, Smaragdi Antonopoulou, Fotios Barkas, Evangelos Liberopoulos, Christina Chrysohoou, Petros P. Sfikakis, Christos Pitsavos, Costas Tsioufis, Demosthenes Panagiotakos   +8 more
wiley   +1 more source