Results 31 to 40 of about 1,961,106 (365)
Macroscopic current generated by local division and apoptosis in a minimal model of tissue dynamics [PDF]
arXiv, 2021 We consider a minimal computational model of tissue dynamics with two active ingredients: local particle division and apoptosis. We neglect other non-equilibrium effects such as self-propulsion. We simulated the steady state dynamics inside an asymmetric channel and we found a net macroscopic current along the channel. Although such macroscopic current
arxiv
Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
Oxidative Medicine and Cellular Longevity, 2019 Reactive oxygen species- (ROS-) induced lipid peroxidation plays a critical role in cell death including apoptosis, autophagy, and ferroptosis. This fundamental and conserved mechanism is based on an excess of ROS which attacks biomembranes, propagates ...
L. Su +7 more
semanticscholar +1 more source
Generation of Tumour-stroma Minispheroids for Drug Efficacy Testing
Bio-Protocol, 2017 The three-dimensional organisation of cells in a tissue and their interaction with adjacent cells and extracellular matrix is a key determinant of cellular responses, including how tumour cells respond to stress conditions or therapeutic drugs (Elliott ...
Mark Watters , Eva Szegezdi
doaj +1 more source
Cells, 2023 Adult stem cells (ASCs) can be cultured with difficulty from most tissues, often requiring chemical or transgenic modification to achieve adequate quantities. We show here that mouse primary fibroblasts, grown in suspension, change from the elongated and
Behzad Yeganeh +4 more
doaj +1 more source
Apoptosis classification using attention based spatio temporal graph convolution neural network [PDF]
arXiv, 2023 Accurate classification of apoptosis plays an important role in cell biology research. There are many state-of-the-art approaches which use deep CNNs to perform the apoptosis classification but these approaches do not account for the cell interaction.
arxiv
Nature Communications, 2018 IRE1/XBP-1 activation has a major role in Triple negative breast cancer (TNBC). Here, the authors show that inhibition of IRE1’s RNase activity attenuates autocrine and paracrine signaling of pro-tumorigenic cytokines and synergizes with paclitaxel to ...
Susan E. Logue +18 more
doaj +1 more source
Effective description of bistability and irreversibility in apoptosis [PDF]
arXiv, 2021 Apoptosis is a mechanism of programmed cell death in which cells engage in a controlled demolition and prepare to be digested without damaging their environment. In normal conditions apoptosis is repressed, until it is irreversibly induced by an appropriate signal.
arxiv
Intestinal apoptotic changes linked to metabolic status in fasted and refed rats [PDF]
Pflugers Arch 451 (03/2006) 749-759, 2007 Intestinal apoptosis and expression of apoptosis inducers - the cytokines TNFalpha, TGFbeta1 - and the intestinal transcription factor Cdx2, were studied according to two different metabolic and hormonal phases which characterize long-term fasting: the long period of protein sparing during which energy expenditure is derived from lipid oxidation (phase
arxiv +1 more source
Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 2014 Apoptozis ya da programlı hücre ölümü sağlıklı çok hücreli organizmada meydana gelen fizyolojik bir olgudur. Bu olgu, temel tıp bilimlerinde anlaşılması güç birçok olayın açıklanmasında kullanılmıştır. Hücre ölümüne sebep olan temel faktörlerden birinin serbest radikaller olduğu bilinmektedir.
MİS, Leyla, YELTEKİN, Aslı Çilingir
openaire +3 more sources