Results 111 to 120 of about 48,450 (301)

Aptamer-based fluorometric determination of Salmonella Typhimurium using Fe₃O₄ magnetic separation and CdTe quantum dots - Fig 5

, 2019
UV-vis absorption spectrum of MNPs@aptamer (curve a) and aptamer (curve b).
Junan Ren (3847069), Gang Liang (120372), An Li (415945), Ligang Pan (762190), Yan Man (6858176), Xinxin Jin (678016), Qingju Liu (2562268)   +6 more
core   +1 more source

Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays

Advanced Science, EarlyView.
An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen, Bin Li, Yingying Wang, Fulin Zhu, Wenxuan Yang, Xuanyu Fu, Tiantian Man, Qiuyue Wu, Kewei Ren, Shengyuan Deng   +9 more
wiley   +1 more source

Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

Molecular Therapy: Nucleic Acids, 2014
Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-stranded DNA oligonucleotides and have high specificity and affinity for their targets.
Hongguang Sun, Xun Zhu, Patrick Y Lu, Roberto R Rosato, Wen Tan, Youli Zu   +5 more
doaj   +1 more source

Aptamer-Based K⁺ Sensor: Process of Aptamer Transforming into G‑Quadruplex

, 2016
G-rich aptamers have been widely applied to develop various sensors for detecting proteins, small molecules, and cations, which is based on the target-induced conformational transfer from single strand to G-quadruplex.
Xiaohong Li (71964), Juan Han (169478), Dongju Zhang (1503739), Yunchao Li (186024), Louzhen Fan (1492348)   +4 more
core   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

DNA origami-enhanced binding of aptamers to Staphylococcus aureus cells

Biosensors and Bioelectronics: X
The combination of DNA origami nanostructures and aptamers provides a powerful technology for diagnostic assays. Here, we functionalized a DNA origami nanostructure with a Protein-A binding aptamer to target Staphylococcus aureus bacterial cells.
Yasaman Ahmadi, Trishant R. Umrekar, Natalie Mutter, Morgan Beeby, Ivan Barišić   +4 more
doaj   +1 more source

Aptamer-mediated doxorubicin delivery reduces HCC burden in 3D organoids model

, 2021
Aptamer-mediated doxorubicin delivery reduces HCC burden in 3D organoids ...
L Yuen (13400019), V Lam (11116986), L Qiao (13318455), Wei Duan (13099662), S Han (7725161), X Huo (13371558), K Zhou (7790216), SDW Bae (14549468), Z Zhang (7695560), J George (7791293), R Nguyen (13400013)   +10 more
core  

Mechanistic Design of Graphdiyne‐Based Multimodal Sensing Integrating Machine Learning and Photothermal Dynamics for Precision Recognition and On‐Demand Inactivation

Advanced Science, EarlyView.
A triple‐mode theranostic platform enables integrated electrochemical, colorimetric, and photothermal detection of bacterial infection. Glucose oxidation triggers H2O2 generation and TMB oxidation to oxTMB, producing color and thermal signals under 808 nm NIR irradiation.
Jing Xu, Hanxiao Chen, Liucun Yin, Yifang Tao, Qichen Yuan, Hong Wang, Huan Pang, Junyan Teng, Li Xue   +8 more
wiley   +1 more source

Aptamer-Directed Conjugation of DNA to Therapeutic Antibodies

, 2019
A method for aptamer directed conjugation of DNA to therapeutic antibodies has been developed. In the method, an antibody selective aptamer binds to a specific site in the constant domain of human IgG1 antibodies and is used for both templated and direct
Michael R. Mortensen, Michael R. Mortensen (6445148), Johan Palmfeldt (199527), Mikkel B. Skovsgaard, Kurt V. Gothelf, Kurt V. Gothelf (1476721), Johan Palmfeldt, Mikkel B. Skovsgaard (6445142)   +7 more
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source