Results 31 to 40 of about 72,832 (299)
Principal factors that determine the extension of detection range in molecular beacon aptamer/conjugated polyelectrolyte bioassays. [PDF]
, 2015 A strategy to extend the detection range of weakly-binding targets is reported that takes advantage of fluorescence resonance energy transfer (FRET)-based bioassays based on molecular beacon aptamers (MBAs) and cationic conjugated polyelectrolytes (CPEs).
Bazan, Guillermo C +5 more
core +1 more source
Biosensors, 2022 Nucleic acid aptamer-based research has focused on achieving the highest performance for bioassays. However, there are limitations in evaluating the affinity for the target analytes in these nucleic acid aptamer-based bioassays.
Yejin Park +4 more
doaj +1 more source
, 2018 Aptamers are in vitro selected oligonucleotides capable of specific, high-affinity binding to a wide variety of target molecules. These features enable their application in diagnostics, therapeutics, targeted delivery, fluorescence imaging, and biosensing.
Andrew Brian Kinghorn (Ed.) +2 more
openaire +1 more source
Incorporation of aptamers in the terminal loop of shRNAs yields an effective and novel combinatorial targeting strategy. [PDF]
, 2017 Gene therapy by engineering patient's own blood cells to confer HIV resistance can potentially lead to a functional cure for AIDS. Toward this goal, we have previously developed an anti-HIV lentivirus vector that deploys a combination of shRNA, ribozyme ...
Castanotto, Daniela +4 more
core +1 more source
Aptamer-based therapeutics and their potential in radiopharmaceutical design [PDF]
, 2007 Aptamers, short, single stranded oligonucleotide entities, have been developed in the past 15 years against a plethora of targets and for a variety of applications.
Ferreira, Catia S. M. +1 more
core +3 more sources
Molecular Docking Insight into the Label-Free Fluorescence Aptasensor for Ochratoxin A Detection
Molecules, 2023 Ochratoxin A (OTA) is the most common mycotoxin and can be found in wheat, corn and other grain products. As OTA pollution in these grain products is gaining prominence as a global issue, the demand to develop OTA detection technology has attracted ...
Hua Ye +7 more
doaj +1 more source
Bionanomedicine: A “Panacea” In Medicine? [PDF]
, 2017 Recent advances in nanotechnology, biotechnology, bioinformatics, and materials science have prompted novel developments in the field of nanomedicine. Enhancements in the theranostics, computational information, and management of diseases/disorders are ...
Anurogo, D. (Dito) +2 more
core +1 more source
Aptamer-Modified Semiconductor Quantum Dots for Biosensing Applications
Sensors, 2017 Semiconductor quantum dots have attracted extensive interest in the biosensing area because of their properties, such as narrow and symmetric emission with tunable colors, high quantum yield, high stability and controllable morphology.
Lin Wen +4 more
doaj +1 more source
Indonesian Journal of Chemistry, 2021 Inaccurate diagnoses contributes to the high mortality rate of breast cancer. Human epidermal growth factor receptor 2 (HER2) is overexpressed in breast cancer tumors at around 20–30%.
Yeni Wahyuni Hartati +5 more
doaj +1 more source
A double safety lock tumor-specific device for suicide gene therapy in breast cancer [PDF]
, 2020 Producción CientíficaThe complexity and continuous evolution of cancer make the design of novel strategies of treatment a constant challenge in biomedicine.
Arias Vallejo, Francisco Javier +5 more
core +2 more sources