Results 41 to 50 of about 72,832 (299)

Hierarchy and assortativity as new tools for affinity investigation: the case of the TBA aptamer-ligand complex

open access: yes, 2017
Aptamers are single stranded DNA, RNA or peptide sequences having the ability to bind a variety of specific targets (proteins, molecules as well as ions).
Alfinito, E., Cataldo, R., Reggiani, L.
core   +1 more source

Integrating microfluidics and biosensing on a single flexible acoustic device using hybrid modes [PDF]

open access: yes, 2020
Integration of microfluidics and biosensing functionalities on a single device holds promise in continuous health monitoring and disease diagnosis for point-of-care applications.
Dodd, Linzi   +10 more
core   +5 more sources

DNA module platform for developing colorimetric aptamer sensors

open access: yesBioTechniques, 2016
Here we present a DNA module platform for developing simple aptamer sensors based on a microarray format combined with secondary structure prediction in silico.
Yasuyuki Tomita   +3 more
doaj   +1 more source

Programmable biomaterials for dynamic and responsive drug delivery [PDF]

open access: yes, 2016
Biomaterials are continually being designed that enable new methods for interacting dynamically with cell and tissues, in turn unlocking new capabilities in areas ranging from drug delivery to regenerative medicine. In this review, we explore some of the
Almquist, BD, Kiani, MT, Stejskalova, A
core   +1 more source

Incorporation of a metal-mediated base pair into an ATP aptamer – using silver(I) ions to modulate aptamer function

open access: yesBeilstein Journal of Organic Chemistry, 2020
For the first time, a metal-mediated base pair has been used to modulate the affinity of an aptamer towards its target. In particular, two artificial imidazole 2’-deoxyribonucleosides (Im) were incorporated into various positions of an established ATP ...
Marius H. Heddinga, Jens Müller
doaj   +1 more source

Stabilizing Enzymes in Plasmonic Silk Film for Synergistic Therapy of In Situ SERS Identified Bacteria

open access: yesAdvanced Science, 2022
Increasing antibiotic resistance becomes a serious threat to public health. Photothermal therapy (PTT) and antibacterial enzyme‐based therapy are promising nonresistant strategies for efficiently killing drug‐resistant bacteria.
Zhangkun Liu   +6 more
doaj   +1 more source

Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity [PDF]

open access: yes, 2010
While many different RNA aptamers have been identified that bind to a plethora of small molecules only very few are capable of acting as engineered riboswitches.
Duchardt-Ferner, Elke   +6 more
core   +1 more source

Detection of okadaic acid using a liquid crystal-based aptasensor by exploiting the signal enhancement effect of gold nanoparticles

open access: yesBiosensors and Bioelectronics: X, 2022
In this work, a liquid crystal (LC)-based aptasensor for okadaic acid (OA) detection was developed with a novel aptamer mechanism for enhancing the optical signals of LCs.
Zeinab Rouhbakhsh   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Critical Design Factors for Electrochemical Aptasensors Based on Target-Induced Conformational Changes: The Case of Small-Molecule Targets

open access: yesBiosensors, 2022
Nucleic-acid aptamers consisting in single-stranded DNA oligonucleotides emerged as very promising biorecognition elements for electrochemical biosensors applied in various fields such as medicine, environmental, and food safety.
Andra Mihaela Onaş   +3 more
doaj   +1 more source

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