Results 51 to 60 of about 72,832 (299)

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Enzyme-mimic activity study of superstable and ultrasmall graphene encapsuled CoRu nanocrystal

APL Materials, 2021
Nanozymes hold huge potential in various fields, but their much lower catalytic activities than natural enzymes greatly limit their extensive applications. Recent studies indicated that an enhanced enzyme-like activity could be obtained by decreasing the
Phouphien Keoingthong, Shengkai Li, Zhaotian Zhu, Liang Zhang, Jieqiong Xu, Long Chen, Weihong Tan, Zhuo Chen   +7 more
doaj   +1 more source

Aptamer–Drug Conjugates [PDF]

Bioconjugate Chemistry, 2015
Western medicine often aims to specifically treat diseased tissues or organs. However, the majority of current therapeutics failed to do so owing to their limited selectivity and the consequent "off-target" side effects. Targeted therapy aims to enhance the selectivity of therapeutic effects and reduce adverse side effects.
Guizhi, Zhu, Gang, Niu, Xiaoyuan, Chen
openaire   +2 more sources

A blue light receptor that mediates RNA binding and translational regulation [PDF]

, 2019
Sensory photoreceptor proteins underpin light-dependent adaptations in nature and enable the optogenetic control of organismal behavior and physiology.
Bittl, Robert, Kaiser, Jennifer, Moniot, Sébastien [u.v.m.], Pietruschka, Georg, Pilsl, Sebastian, Renzl, Christian, Schrottke, Stefanie, Sixt, Lisa, Weber, Anna M., Ziegler, Thea   +9 more
core   +1 more source

Multi‐Scale Interface Engineering of MXenes for Multifunctional Sensory Systems

Advanced Functional Materials, EarlyView.
MXenes, as two‐dimensional transition metal carbides and nitrides, demonstrate remarkable capabilities for multifunctional sensing applications. This review systematically examines multi‐scale interface engineering approaches that enhance sensing performance, enable diverse detection functionalities, and improve system‐level compatibility in MXene ...
Jiaying Liao, Sin‐Yi Pang, Jianhua Hao
wiley   +1 more source

Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer

Molecular Therapy: Nucleic Acids, 2015
Aptamers are valuable tools that provide great potential to develop cost-effective diagnostics and therapies in the biomedical field. Here, we report a novel DNA aptamer that folds into an unconventional G-quadruplex structure able to recognize and enter
Felipe Opazo, Laura Eiden, Line Hansen, Falk Rohrbach, Jesper Wengel, Jørgen Kjems, Günter Mayer   +6 more
doaj   +1 more source

A DNA aptamer for binding and inhibition of DNA methyltransferase 1. [PDF]

, 2019
DNA methyltransferases (DNMTs) are enzymes responsible for establishing and maintaining DNA methylation in cells. DNMT inhibition is actively pursued in cancer treatment, dominantly through the formation of irreversible covalent complexes between small ...
Adkins, Gary Brent, Duan, Yaokai, Fang, Jian, Gao, Linfeng, Jimenez, Luis A, Lee, Ju Yong, Li, Linhui, Ren, Wendan, Song, Jikui, Wang, Linlin, Wang, Yinsheng, Yin, Jiekai, Zhong, Wenwan   +12 more
core  

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

Advanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou, Barbara Spagnolo, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello   +4 more
wiley   +1 more source

DNA-Based Molecular Machines: Controlling Mechanisms and Biosensing Applications

Biosensors
The rise of DNA nanotechnology has driven the development of DNA-based molecular machines, which are capable of performing specific operations and tasks at the nanoscale. Benefitting from the programmability of DNA molecules and the predictability of DNA
Chunran Ma, Shiquan Li, Yuqi Zeng, Yifan Lyu   +3 more
doaj   +1 more source

Aptamers in Immunotherapy [PDF]

Human Gene Therapy, 2008
Numerous nucleic acid ligands, also termed decoys or aptamer, have been developed during the past 20 years that can bind to and inhibit the activity of many proteins. The concept that nucleic acid ligands could modulate the activity of proteins emerged from basic science studies of viruses and early work in the field of gene therapy.
Claudia M, Dollins, Smita, Nair, Bruce A, Sullenger   +2 more
openaire   +2 more sources