Results 81 to 90 of about 53,726 (303)

Aptamer-Based Paper Strip Sensor for Detecting Vibrio fischeri

open access: yes, 2018
Aptamer-based paper strip sensor for detecting Vibrio fischeri was developed. Our method was based on the aptamer sandwich assay between whole live cells, V. fischeri and DNA aptamer probes. Following 9 rounds of Cell-SELEX and one of the negative-SELEX,
Woo-Ri Shin (4993184)   +6 more
core   +1 more source

Aptamer-Based Sensing of Small Organic Molecules by Measuring Levitation Coordinate of Single Microsphere in Combined Acoustic–Gravitational Field

open access: yes, 2020
We present aptamer-based sensing using a coupled acoustic-gravitational (CAG) field, which transduces a change in the density of a microparticle (MP) to a change in the levitation coordinate.
Akihisa Miyagawa (4789803)   +2 more
core   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang   +8 more
wiley   +1 more source

Microenvironment-confined kinetic elucidation and implementation of a DNA nano-phage with a shielded internal computing layer

open access: yesNature Communications
Multiple receptor analysis-based DNA molecular computation has been developed to mitigate the off-target effect caused by nonspecific expression of cell membrane receptors.
Decui Tang   +9 more
doaj   +1 more source

Pharmacokinetics of a Cholesterol-conjugated Aptamer Against the Hepatitis C Virus (HCV) NS5B Protein

open access: yesMolecular Therapy: Nucleic Acids, 2015
Hepatitis C virus (HCV) is the major cause of progressive liver disease such as chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Previously, we reported that a 29 nucleotide-long 2’-F pyrimidine modified RNA aptamer against the HCV ...
Chang Ho Lee   +5 more
doaj   +1 more source

Probing high affinity sequences of DNA aptamer against VEGF165. [PDF]

open access: yesPLoS ONE, 2012
Vascular endothelial growth factor (VEGF(165)) is a potent angiogenic mitogen commonly overexpressed in cancerous cells. It contains two main binding domains, the receptor-binding domain (RBD) and the heparin-binding domain (HBD). This study attempted to
Harleen Kaur, Lin-Yue Lanry Yung
doaj   +1 more source

Aptamer-DNA Origami-Functionalized Solid-State Nanopores for Single-Molecule Sensing of G‑Quadruplex Formation

open access: yes, 2022
We describe the single-molecule sensing of G-quadruplex (G-q) formation in target-bound aptamers using solid-state nanopores. In order to do this, we functionalize the solid-state nanopore using DNA origami sheets incorporated with the aptamer sequence ...
Manoj M. Varma (2802064)   +4 more
core   +1 more source

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

open access: yesAdvanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos   +17 more
wiley   +1 more source

Recent Advances in Aptamer-Based Point-of-Care Testing

open access: yesSensors
Aptamers refer to a class of oligonucleotide probes that have demonstrated remarkable capabilities beyond mere genetic coding, including the unique ability to recognize and selectively bind to specific molecular targets.
Senlin Luo   +6 more
doaj   +1 more source

Aptamer-guided extracellular vesicle theranostics in oncology

open access: yes, 2020
Aptamer-guided extracellular vesicle theranostics in ...
Y Ma (7409624)   +16 more
core  

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