Results 161 to 170 of about 581,942 (266)
Application Strategies of Bone Marrow Mesenchymal Stromal Cells in Bone‐Related Diseases
Cell Proliferation, EarlyView.Engineered BMSCs and vesicles enhance therapy effects for bone diseases via multi‐strategic approaches. ABSTRACT Bone‐related diseases (e.g., osteoporosis, osteoarthritis and fractures) exhibit a rising global incidence, imposing significant burdens on both quality of life and healthcare systems.
Xuemei Long +6 more
wiley +1 more source
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury
Experimental Physiology, EarlyView.Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley +1 more source
RiboaptDB: A Comprehensive Database of Ribozymes and Aptamers
BMC Bioinformatics, 2006 Background Catalytic RNA molecules are called ribozymes. The aptamers are DNA or RNA molecules that have been selected from vast populations of random sequences, through a combinatorial approach known as SELEX.
Thodima Venkata +2 more
doaj +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, Volume 16, Issue 2, Page 299-313, February 2026.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes
Advanced Therapeutics, Volume 9, Issue 2, February 2026.Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava +9 more
wiley +1 more source
Light‐Up Sensing Citrate Using a Capture‐Selected DNA Aptamer
Advanced Sensor ResearchCitrate is a key metabolite and nutrient in humans. Its level is associated with many diseases from tumor growth to bone diseases. Detection of citrate has relied on its high negative charge, metal chelating properties and as an enzyme substrate. In this
Lide Gu +3 more
doaj +1 more source
Advanced Science, Volume 13, Issue 8, 9 February 2026.A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Mengjie Wang +10 more
wiley +1 more source
Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications
Aggregate, Volume 7, Issue 2, February 2026.The review discusses the fundamental properties of ultrasmall gold nanoclusters and their surface modification strategies for targeted biomedical use. It examines biologically guided assembly processes and their effects on optical behavior, particularly aggregation‐induced emission.
Zeineb Ayed +3 more
wiley +1 more source
Generation of high-affinity DNA aptamers using non-natural nucleotides [PDF]
Science-Business eXchange, 2013 openaire +1 more source