Results 251 to 260 of about 88,342 (327)

CSF proteomic profiling with amyloid and tau pathology identifies distinctive sex-specific alteration of multiple proteins involved in Alzheimer's disease. [PDF]

Alzheimers Dement
Do AN, Song S, Ali M, Timsina J, Wang L, Western D, Liu M, Sanford J, Rosende-Roca M, Boada M, Puerta R, Wilson EN, Ruiz A, Pastor P, Alzheimer's Disease Neuroimaging Initiative (ADNI), Wyss-Coray T, Cruchaga C, Sung YJ.   +17 more
europepmc   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

When the Position of Pendant Groups Makes the Difference in G-Quadruplex Behavior: The Case of Bis-Conjugated Thrombin-Binding Aptamers. [PDF]

J Chem Inf Model
Platella C, Battistini F, Riccardi C, Smietana M, Morvan F, Orozco M, Montesarchio D.   +6 more
europepmc   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

Rare Metals, EarlyView.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang, Jiatong Lin, Yi Peng, Zehua Wu, Yingying Liu, Wei Duan, Qiaolin Wei, Jia‐Wei Shen, Jiang‐Xing Chen, Yong Guo   +9 more
wiley   +1 more source

Design and Evaluation of Sticky End-Type Bivalent DNA Aptamers Containing M08s-1 as Anticoagulant Agents. [PDF]

ChemMedChem
Yokomori M, Murasawa M, Matsuo M, Nagano M, Yoshimoto K.   +4 more
europepmc   +1 more source

Designer DNA‐Based Machines

SmartBot, EarlyView.
DNA machinery represents a burgeoning frontier at the intersection of robotics and nanotechnology, evolving from static nanostructure toward dynamic nanorobots. Here, the authors review the comprehensive research pipeline of designer DNA‐based nanomachines, covering the design, analysis, and fabrication. These programmable systems enable transformative
Yiquan An, Fan Wu, Yanyu Xiong, Cheng Zhang, Jian S. Dai, Lifeng Zhou   +5 more
wiley   +1 more source

Innovative aptamer approaches in glial tumor diagnostics and therapy: Progress and future directions. [PDF]

Mol Ther Nucleic Acids
Luzan NA, Zamay TN, Zhang P, Narodov AA, Zamay GS, Kichkailo AS, Berezovski MV, Kolovskaya OS.   +7 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Reagentless Real-Time ATP Monitoring with New DNA Aptamers. [PDF]

Small
Bacon A, Alkhamis O, Byrd C, Perry J, Canoura J, Xiao Y.   +5 more
europepmc   +1 more source

Mesoporous Materials for Electrochemical Biosensors: From Broad Structure to Silica Film

Small, EarlyView.
This review showcases how mesoporous materials advance biosensing, spanning from material classes and fabrication strategies to the unique role of silica films as functional sensing platforms. With tunable porosity, high surface area, and versatile chemistry, these materials enhance selectivity and signal amplification in biosensors.
Vinh Khanh Ho, Tuan‐Khoa Nguyen, Sina Jamali, Nam‐Trung Nguyen   +3 more
wiley   +1 more source