Results 41 to 50 of about 31,079 (257)

Aptamers and Cancer

Asian Pacific Journal of Cancer Biology, 2016
Oligonucleotides Aptamers are single strands of DNA and RNA with the length of 20-100 nucleotides or peptides and unique three dimensional structure that is affected by nucleotide sequence. The structure exclusively influences aptamers’ bindings with its target molecule.
Yazdanpanahi, Nasrin, Hashemi, Mehrdad, Movafagh, Abolfazl   +2 more
openaire   +4 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Hierarchical core–shell DNA condensates enable programmable information storage and encryption

Nature Communications
Utilizing DNA’s molecular programmability, massive parallelism, and minimal energy requirements, it emerges as a transformative medium for secure data storage and encryption.
Likang Chu, Liqi Wan, Haixia Wang, Peng Wang, Linyi Deng, Yuan Gao, Pei Guo, Lei He, Da Han   +8 more
doaj   +1 more source

Recent Advances in Fluorescent Nanoparticles for Stimulated Emission Depletion Imaging

Biosensors
Stimulated emission depletion (STED) microscopy, as a popular super-resolution imaging technique, has been widely used in bio-structure analysis and resolving the dynamics of biological processes beyond the diffraction limit.
Liqing Qi, Songlin Liu, Jiantao Ping, Xingxing Yao, Long Chen, Dawei Yang, Yijun Liu, Chenjing Wang, Yating Xiao, Lubin Qi, Yifei Jiang, Xiaohong Fang   +11 more
doaj   +1 more source

Applications of Aptamer-Bound Nanomaterials in Cancer Therapy

Biosensors, 2021
Cancer is still a major disease that threatens human life. Although traditional cancer treatment methods are widely used, they still have many disadvantages.
Liangxi Zhu, Jingzhou Zhao, Zhukang Guo, Yuan Liu, Hui Chen, Zhu Chen, Nongyue He   +6 more
doaj   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

Intraperitoneal programming of tailored CAR macrophages via mRNA lipid nanoparticle to boost cancer immunotherapy

Nature Communications
Therapeutic strategies for peritoneal metastasis in solid tumors are urgently needed. Programming chimeric antigen receptor macrophages (CAR-Ms) in situ offers opportunities for an unmet demand.
Kedan Gu, Ting Liang, Luting Hu, Yifan Zhao, Weiyang Ying, Mengke Zhang, Yashuang Chen, Benmeng Liang, Xinrui Lin, Yanqi Zhang, Hongyu Wu, Meng Wang, Yuping Zhu, Wenxi Wang, Yu Zhang, Chao Zuo, Zhen Du, Penghui Zhang, Jia Song, Liwen Li, Xiangsheng Liu, Sitao Xie, Weihong Tan   +22 more
doaj   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source

Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo

Journal of Nucleic Acids, 2017
The binding specificity and affinity of aptamers have long been harnessed as the key elements in the development of aptamer-based assays, particularly aptasensing application.
Mawethu Pascoe Bilibana, Marimuthu Citartan, Tzi Shien Yeoh, Timofey S. Rozhdestvensky, Thean-Hock Tang   +4 more
doaj   +1 more source

DNA Aptamers in the Diagnosis and Treatment of Human Diseases

Molecules, 2015
Aptamers have a promising role in the field of life science and have been extensively researched for application as analytical tools, therapeutic agents and as vehicles for targeted drug delivery.
Qinchang Zhu, Ge Liu, Masaaki Kai
doaj   +1 more source