Results 41 to 50 of about 78,567 (340)
Combined aptamer and transcriptome sequencing of single cells. [PDF]
, 2018 The transcriptome and proteome encode distinct information that is important for characterizing heterogeneous biological systems. We demonstrate a method to simultaneously characterize the transcriptomes and proteomes of single cells at high throughput ...
Abate, Adam R +3 more
core +2 more sources
Scientific Reports, 2021 Tosyl activated magnetic beads were used for aptamer selection against PAG- 7 and 18 proteins of bovine origin. PAG proteins were immobilized on beads with further addition of biotin tagged aptamer library.
Munna Lal Yadav +5 more
doaj +1 more source
Electrochemistry, 2021 Field effect transistor (FET) biosensors are capable of detecting various biomolecules, although challenges remain in the detection of uncharged molecules.
Hiroki HAYASHI +9 more
doaj +1 more source
A Realistic Model under which the Genetic Code is Optimal [PDF]
, 2013 The genetic code has a high level of error robustness. Using values of hydrophobicity scales as a proxy for amino acid character, and the Mean Square measure as a function quantifying error robustness, a value can be obtained for a genetic code which ...
Buhrman, Harry +5 more
core +12 more sources
A blue light receptor that mediates RNA binding and translational regulation [PDF]
, 2019 Sensory photoreceptor proteins underpin light-dependent adaptations in nature and enable the optogenetic control of organismal behavior and physiology.
Bittl, Robert +9 more
core +1 more source
Aptamers and Their Biological Applications [PDF]
Sensors, 2012 Recently, aptamers have attracted the attention of many scientists, because they not only have all of the advantages of antibodies, but also have unique merits, such as thermal stability, low cost, and unlimited applications. In this review, we present the reasons why aptamers are known as alternatives to antibodies.
Song, KM, Lee, S, Ban, C
openaire +4 more sources
Pharmaceutics, 2021 Nucleic acid aptamers have attracted considerable attention as next-generation pharmaceutical agents and delivery vehicles for small molecule drugs and therapeutic oligonucleotides.
Hiro Uemachi +5 more
doaj +1 more source
Biosensors, 2017 In the last years, great progress has been accomplished in the development of aptamer sensors with different transducers. In order to improve the sensitivity of these biosensors, several methodologies have been employed. In this Special Issue, the state of art and the future trends in the field of aptamer sensors have been explored.
openaire +4 more sources
Molecular Therapy: Nucleic Acids, 2023 Here, we present DNA aptamers capable of specific binding to glial tumor cells in vitro, ex vivo, and in vivo for visualization diagnostics of central nervous system tumors.
Anna S. Kichkailo +54 more
doaj +1 more source
A double safety lock tumor-specific device for suicide gene therapy in breast cancer [PDF]
, 2020 Producción CientíficaThe complexity and continuous evolution of cancer make the design of novel strategies of treatment a constant challenge in biomedicine.
Arias Vallejo, Francisco Javier +5 more
core +2 more sources