Results 41 to 50 of about 41,171 (288)
Acta Biomedica Scientifica, 2022 Background. Aptamers are small single-stranded DNA or RNA molecules that have an affinity for a specific target molecule. The main method of aptamers construction is the technology of systematic evolution of ligands with exponential enrichment (SELEX ...
I. S. Solovarov +4 more
doaj +1 more source
Asian Pacific Journal of Cancer Biology, 2016 Oligonucleotides Aptamers are single strands of DNA and RNA with the length of 20-100 nucleotides or peptides and unique three dimensional structure that is affected by nucleotide sequence. The structure exclusively influences aptamers’ bindings with its target molecule.
Yazdanpanahi, Nasrin +2 more
openaire +4 more sources
DNA Aptamers against Taiwan Banded Krait α-Bungarotoxin Recognize Taiwan Cobra Cardiotoxins
Toxins, 2016 Bungarus multicinctus α-bungarotoxin (α-Bgt) and Naja atra cardiotoxins (CTXs) share a common structural scaffold, and their tertiary structures adopt three-fingered loop motifs. Four DNA aptamers against α-Bgt have been reported previously.
Ying-Jung Chen +3 more
doaj +1 more source
Forced Intercalation (FIT)-Aptamers
, 2019 Aptamers are oligonucleotide sequences that can be evolved to bind to various analytes of interest. Here, we present a general design strategy that transduces an aptamer-target binding event into a fluorescence readout via the use of a viscosity ...
Chad A. Mirkin (16519) +4 more
core +1 more source
Sensing and Bio-Sensing Research, 2021 Leukemia is a deadly cancer disease, and according to World Health Organization (WHO) data, there were 437,033 cases across the world in 2018. Early detection of this cancer is very difficult, as its symptoms are hidden and clinically invisible ...
Yuspian Nur +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Biological Procedures OnlineExosomes are increasingly recognized as important mediators of intercellular communication in cancer biology. Exosomes can be derived from cancer cells as well as cellular components in tumor microenvironment.
Yating Wu +5 more
doaj +1 more source
Screening and Application of DNA Aptamers for Heparin-Binding Protein
MoleculesRapid detection of heparin-binding protein (HBP) is essential for timely intervention in sepsis cases. Current detection techniques are usually antibody-based immunological methods, which have certain problems, such as complexity and slow detection, and ...
Xi Zhou +9 more
doaj +1 more source
The life marker chip : potential use of aptamers against small molecules and consideration of instrument planetary protection [PDF]
, 2013 The Life Marker Chip (LMC) instrument was developed with the aim to detect evidence of life on Mars. The detection was based on an inhibition immunoassay. In this work aptamers were evaluated as potential alternative to antibodies for the LMC.
Rato, Carla Cristina Pereira Salgueiro Catarino
core
Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review
Advanced Functional Materials, EarlyView.Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera +6 more
wiley +1 more source