Results 11 to 20 of about 41,663 (295)
Frontiers in Immunology, 2022 Microglial and astrocyte activation and related cytokine secretion play key roles in secondary brain injury following intracerebral hemorrhage (ICH). We assessed the role of aquaporin (AQP)2 in immune response after ICH.
Shuwen Deng +3 more
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Glucocorticoid Receptor Maintains Vasopressin Responses in Kidney Collecting Duct Cells
Frontiers in Physiology, 2022 Water permeability of the kidney collecting ducts is regulated in part by the amount of the molecular water channel protein aquaporin-2 (AQP2), whose expression, in turn, is regulated by the pituitary peptide hormone vasopressin.
Hsiu-Hui Yang +5 more
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Aquaporin-2 in the “-omics” Era [PDF]
Journal of Biological Chemistry, 2009 Vasopressin controls renal water excretion largely through actions to regulate the water channel aquaporin-2 in collecting duct principal cells. Our knowledge of the mechanisms involved has increased markedly in recent years with the advent of methods for large-scale systems-level profiling such as protein mass spectrometry, yeast two-hybrid analysis ...
Jason D, Hoffert +2 more
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Minireview: Aquaporin 2 Trafficking [PDF]
Endocrinology, 2005 In the kidney aquaporin-2 (AQP2) provides a target for hormonal regulation of water transport by vasopressin. Short-term control of water permeability occurs via vesicular trafficking of AQP2 and long-term control through changes in the abundance of AQP2 and AQP3 water channels.
VALENTI, Giovanna +4 more
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Vasopressin and the regulation of aquaporin-2 [PDF]
Clinical and Experimental Nephrology, 2013 Water excretion is regulated in large part through the regulation of osmotic water permeability of the renal collecting duct epithelium. Water permeability is controlled by vasopressin through regulation of the water channel, aquaporin-2 (AQP2).
Justin L L, Wilson +2 more
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The Role of Vasopressin V2 Receptor in Drug-Induced Hyponatremia
Frontiers in Physiology, 2021 Hyponatremia is frequently encountered in clinical practice and usually induced by renal water retention. Many medications are considered to be among the various causes of hyponatremia, because they either stimulate the release of arginine vasopressin ...
Sua Kim +3 more
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Ubiquitination of Aquaporin-2 in the Kidney [PDF]
Electrolytes & Blood Pressure, 2009 Ubiquitination is known to be important for endocytosis and lysosomal degradation of aquaporin-2 (AQP2). Ubiquitin (Ub) is covalently attached to the lysine residue of the substrate proteins and activation and attachment of Ub to a target protein is mediated by the action of three enzymes (i.e., E1, E2, and E3). In particular, E3 Ub-protein ligases are
Lee, Yu-Jung, Kwon, Tae-Hwan
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Frontiers in Physiology, 2023 Arginine vasopressin (AVP) induces an increase in intracellular Ca2+ concentration ([Ca2+]i) with an oscillatory pattern in isolated perfused kidney inner medullary collecting duct (IMCD).
Kay-Pong Yip +7 more
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Journal of the American Society of Nephrology, 2013 The critical contribution of aquaporin-2 (AQP) to water homeostasis in mammals is highlighted by the severe concentrating defects seen in humans with mutations in the AQP2 gene and in mice that are AQP2 null or have loss-of-function mutations in AQP2 .[1][1],[2][2] The role of the ...
Dennis, Brown, Hua A Jenny, Lu
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Frontiers in Endocrinology, 2021 ObjectiveMutations in AQP2 (aquaporin-2) lead to rare congenital nephrogenic diabetes insipidus (NDI), which has been limitedly studied in Chinese population.MethodsTwenty-five subjects from seven families with NDI in a department (Beijing, PUMCH) were ...
Qian Li +4 more
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