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Aquaporin-2 (AQP2) is a molecular water channel protein responsible for water reabsorption by the kidney collecting ducts. Many water balance disorders are associated with defects in AQP2 gene expression regulated by the peptide hormone vasopressin. Here,
Shu-Ting Lin +10 more
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BackgroundRecognizing the predictors of disease relapses in patients with anti-aquaporin-4 antibody (AQP4-ab)-positive neuromyelitis optica spectrum disorder (NMOSD) is essential for individualized treatment strategy.
Yuanqi Zhao (677914) +25 more
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Nuclear Receptor Regulation of Aquaporin-2 in the Kidney [PDF]
Aquaporin-2 (AQP2) is a vasopressin-regulated water channel responsible for regulating water reabsorption through the apical plasma membrane of the principal cells of renal collecting ducts. It has been found that dysregulation and dysfunction of AQP2 cause many disorders related to water balance in people and animals, including polyuria and dilutional
Zhang, Xiao-Yan +2 more
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BackgroundRecognizing the predictors of disease relapses in patients with anti-aquaporin-4 antibody (AQP4-ab)-positive neuromyelitis optica spectrum disorder (NMOSD) is essential for individualized treatment strategy.
Yuanqi Zhao (677914) +25 more
core +1 more source
BackgroundRecognizing the predictors of disease relapses in patients with anti-aquaporin-4 antibody (AQP4-ab)-positive neuromyelitis optica spectrum disorder (NMOSD) is essential for individualized treatment strategy.
Yuanqi Zhao (677914) +25 more
core +1 more source
Aquaporin-2 membrane targeting: still a conundrum [PDF]
The targeting of the water channel aquaporin-2 (AQP2) to the apical plasma membrane of kidney collecting duct principal cells is regulated mainly by the antidiuretic peptide hormone arginine vasopressin (AVP). This process is of crucial importance for the maintenance of body water homeostasis.
Olesen, Emma Tina Bisgaard +1 more
openaire +5 more sources
The Clinical Importance of the Urinary Excretion of Aquaporin-2 [PDF]
The movement of water across the cell membranes of an organism is of central importance in many functions.
Knoers, N.V.A.M., Os, C.H. van
openaire +2 more sources
Small-Molecule Screening Identifies Modulators of Aquaporin-2 Trafficking [PDF]
Contains fulltext : 117665.pdf (Publisher’s version ) (Closed access)In the principal cells of the renal collecting duct, arginine vasopressin (AVP) stimulates the synthesis of cAMP, leading to signaling events that culminate in the ...
Kries, J.P. von +45 more
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In ischemic stroke, vasopressin hypersecretion is a critical factor of cerebral swelling and brain injury. To clarify neural mechanisms underlying ischemic stroke-evoked vasopressin hypersecretion, we observed the effect of unilateral permanent middle ...
Dan Cui +9 more
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Effect of Diet and Water Intake on Aquaporin 2 Function [PDF]
Appropriate control of diet and water intake is important for maintaining normal blood pressure, fluid and electrolyte homeostasis in the body. It is relatively understood that the amount of sodium and potassium intake directly affects blood pressure and
Jun-Mo Kim, Tae-Hee Kim, Tong Wang
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