Results 31 to 40 of about 38,213 (256)
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2019 Review on aquaporin-2 (AQP2), with data on DNA, on the protein encoded, and where the gene is implicated.
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Nuclear Receptor Regulation of Aquaporin-2 in the Kidney [PDF]
International Journal of Molecular Sciences, 2016 Aquaporin-2 (AQP2) is a vasopressin-regulated water channel responsible for regulating water reabsorption through the apical plasma membrane of the principal cells of renal collecting ducts. It has been found that dysregulation and dysfunction of AQP2 cause many disorders related to water balance in people and animals, including polyuria and dilutional
Zhang, Xiao-Yan +2 more
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Effect of Diet and Water Intake on Aquaporin 2 Function [PDF]
Childhood Kidney Diseases, 2016 Appropriate control of diet and water intake is important for maintaining normal blood pressure, fluid and electrolyte homeostasis in the body. It is relatively understood that the amount of sodium and potassium intake directly affects blood pressure and
Jun-Mo Kim, Tae-Hee Kim, Tong Wang
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ASN Neuro, 2020 In ischemic stroke, vasopressin hypersecretion is a critical factor of cerebral swelling and brain injury. To clarify neural mechanisms underlying ischemic stroke-evoked vasopressin hypersecretion, we observed the effect of unilateral permanent middle ...
Dan Cui +9 more
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Quantitative analysis of aquaporin-2 phosphorylation
American Journal of Physiology-Renal Physiology, 2010 The action of vasopressin in rodent collecting ducts to regulate water permeability depends in part on increases in phosphorylation of the water channel aquaporin-2 (AQP2) at three sites: Ser256, Ser264, and Ser269. Previous studies of AQP2 phosphorylation have depended largely on qualitative data using protein mass spectrometry and phospho-specific ...
Xie, Luke +6 more
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Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
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Physiological Reports, 2021 Although several studies have shown that release of water channel proteins, aquaporin 1 (AQP1) and AQP2 in urinary extracellular vesicles (uEV‐AQP1 and ‐AQP2), were altered in experimental kidney injury models, their release in human chronic kidney ...
Sayaka Oshikawa‐Hori +4 more
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Structure of Aquaporin-2 Vasopressin Water Channel [PDF]
Journal of Biological Chemistry, 1996 Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel in the kidney collecting duct. AQP-2 is selectively permeable to water molecule and is translocated between the apical membrane and subapical endosomes in response to vasopressin. To investigate the localization and structure of the aqueous pathway of the AQP-2 water channel, a series of site-
L, Bai, K, Fushimi, S, Sasaki, F, Marumo
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
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Trafficking mechanism of water channel aquaporin‐2 [PDF]
Biology of the Cell, 2005 Targeted positioning of the water channel AQP2 (aquaporin‐2) strictly regulates body water homoeostasis. Trafficking of AQP2 to the apical membrane is critical for the reabsorption of water in renal collecting ducts. In addition to the cAMP‐mediated effect of vasopressin on AQP2 trafficking to the apical membrane, other signalling cascades can also ...
Yumi, Noda, Sei, Sasaki
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