Results 31 to 40 of about 41,663 (295)

The AQP2 mutation V71M causesnephrogenic diabetes insipidus in humans but does not impair the function of a bacterial homolog

open access: yesFEBS Open Bio, 2015
Several point mutations have been identified in human aquaporins, but their effects on the function of the respective aquaporins are mostly enigmatic. We analyzed the impact of the aquaporin 2 mutation V71M, which causesnephrogenic diabetes insipidus in ...
Noreen Klein   +3 more
doaj   +1 more source

Aquaporin‐2 regulation in health and disease [PDF]

open access: yesVeterinary Clinical Pathology, 2012
AbstractAquaporin‐2 (AQP2), the vasopressin‐regulated water channel of the renal collecting duct, is dysregulated in numerous disorders of water balance in people and animals, including those associated with polyuria (urinary tract obstruction, hypokalemia, inflammation, and lithium toxicity) and with dilutional hyponatremia (syndrome of inappropriate ...
M Judith, Radin   +7 more
openaire   +2 more sources

Aquaporin-4 expression in distal myopathy with rimmed vacuoles

open access: yesBMC Neurology, 2012
Background Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle fibers with rimmed vacuoles.
Hoshi Akihiko   +5 more
doaj   +1 more source

P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]

open access: yes, 2008
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
Brian F. King   +29 more
core   +1 more source

Aquaporin-2 in the immature rat [PDF]

open access: yesJournal of the American Society of Nephrology, 1997
The immature kidney is resistant to arginine vasopressin. To define the role of aquaporin-2 (AQP-2), the developmental expression of this water channel was studied in rats. AQP-2 levels were lower during early postnatal life, reaching maximal expression at 10 wk of age. Concurrently, urine osmolality increased from 242 +/- 60 to 1267 +/- 311 mosmol/kg.
M, Bonilla-Felix, W, Jiang
openaire   +2 more sources

Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells

open access: yesFrontiers in Physiology, 2019
Aquaporin-2 (AQP2) is a molecular water channel protein responsible for water reabsorption by the kidney collecting ducts. Many water balance disorders are associated with defects in AQP2 gene expression regulated by the peptide hormone vasopressin. Here,
Shu-Ting Lin   +10 more
doaj   +1 more source

The influence of high and low levels of estrogen on diurnal urine regulation in young women [PDF]

open access: yes, 2008
: BACKGROUND: Sex hormones have a pronounced effect on arginine vasopressin (AVP), and therefore on the diurnal water homeostasis. Low and high levels of plasma-estradiol as seen in the follicular phase of the menstrual cycle may therefore alter the ...
Charlotte Graugaard-Jensen   +4 more
core   +2 more sources

Oxytocin regulates the expression of aquaporin 5 in the late-pregnant rat uterus [PDF]

open access: yes, 2014
Aquaporins (AQPs) are integral membrane channels responsible for the transport of water across a cell membrane. Based on reports that AQPs are present and accumulate in the female reproductive tract late in pregnancy, our aim was to study the expression
Agre   +29 more
core   +1 more source

AQP2 (aquaporin 2) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2019
Review on aquaporin-2 (AQP2), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +2 more sources

Nuclear Receptor Regulation of Aquaporin-2 in the Kidney [PDF]

open access: yesInternational Journal of Molecular Sciences, 2016
Aquaporin-2 (AQP2) is a vasopressin-regulated water channel responsible for regulating water reabsorption through the apical plasma membrane of the principal cells of renal collecting ducts. It has been found that dysregulation and dysfunction of AQP2 cause many disorders related to water balance in people and animals, including polyuria and dilutional
Zhang, Xiao-Yan   +2 more
openaire   +2 more sources

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