Results 31 to 40 of about 41,663 (295)
Several point mutations have been identified in human aquaporins, but their effects on the function of the respective aquaporins are mostly enigmatic. We analyzed the impact of the aquaporin 2 mutation V71M, which causesnephrogenic diabetes insipidus in ...
Noreen Klein +3 more
doaj +1 more source
Aquaporin‐2 regulation in health and disease [PDF]
AbstractAquaporin‐2 (AQP2), the vasopressin‐regulated water channel of the renal collecting duct, is dysregulated in numerous disorders of water balance in people and animals, including those associated with polyuria (urinary tract obstruction, hypokalemia, inflammation, and lithium toxicity) and with dilutional hyponatremia (syndrome of inappropriate ...
M Judith, Radin +7 more
openaire +2 more sources
Aquaporin-4 expression in distal myopathy with rimmed vacuoles
Background Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle fibers with rimmed vacuoles.
Hoshi Akihiko +5 more
doaj +1 more source
P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
Brian F. King +29 more
core +1 more source
Aquaporin-2 in the immature rat [PDF]
The immature kidney is resistant to arginine vasopressin. To define the role of aquaporin-2 (AQP-2), the developmental expression of this water channel was studied in rats. AQP-2 levels were lower during early postnatal life, reaching maximal expression at 10 wk of age. Concurrently, urine osmolality increased from 242 +/- 60 to 1267 +/- 311 mosmol/kg.
M, Bonilla-Felix, W, Jiang
openaire +2 more sources
Aquaporin-2 (AQP2) is a molecular water channel protein responsible for water reabsorption by the kidney collecting ducts. Many water balance disorders are associated with defects in AQP2 gene expression regulated by the peptide hormone vasopressin. Here,
Shu-Ting Lin +10 more
doaj +1 more source
The influence of high and low levels of estrogen on diurnal urine regulation in young women [PDF]
: BACKGROUND: Sex hormones have a pronounced effect on arginine vasopressin (AVP), and therefore on the diurnal water homeostasis. Low and high levels of plasma-estradiol as seen in the follicular phase of the menstrual cycle may therefore alter the ...
Charlotte Graugaard-Jensen +4 more
core +2 more sources
Oxytocin regulates the expression of aquaporin 5 in the late-pregnant rat uterus [PDF]
Aquaporins (AQPs) are integral membrane channels responsible for the transport of water across a cell membrane. Based on reports that AQPs are present and accumulate in the female reproductive tract late in pregnancy, our aim was to study the expression
Agre +29 more
core +1 more source
Review on aquaporin-2 (AQP2), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire +2 more sources
Nuclear Receptor Regulation of Aquaporin-2 in the Kidney [PDF]
Aquaporin-2 (AQP2) is a vasopressin-regulated water channel responsible for regulating water reabsorption through the apical plasma membrane of the principal cells of renal collecting ducts. It has been found that dysregulation and dysfunction of AQP2 cause many disorders related to water balance in people and animals, including polyuria and dilutional
Zhang, Xiao-Yan +2 more
openaire +2 more sources

