Changes in Blood Cells and Complements During Relapse Prevention Therapies for Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder. [PDF]
Kuroda H +15 more
europepmc +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
The Glymphatic-Venous Axis in Brain Clearance Failure: Aquaporin-4 Dysfunction, Biomarker Imaging, and Precision Therapeutic Frontiers. [PDF]
Costea D +7 more
europepmc +1 more source
Glucose Transporter 1 in Health and Disease
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai +3 more
wiley +1 more source
Aquaporin-4 deficiency induced white matter injury via upregulated complement component 3 in cerebral small vessel disease. [PDF]
Chen Y +5 more
europepmc +1 more source
Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley +1 more source
Aquaporin-4 triggers inflammation in a murine endotoxin-induced uveitis (EIU) model. [PDF]
Wang Q +13 more
europepmc +1 more source
ABSTRACT Purpose Magnetization transfer (MT) and water exchange via permeability operate on a similar spatiotemporal scale to water diffusion. In this study, we use a simulation‐based approach to characterize how MT and permeability impact (1) diffusion‐weighted MRI (dMRI) measurements from cylindrical substrates and (2) parameter estimation using a ...
Zhiyu Zheng +3 more
wiley +1 more source
Aquaporin-4 as a cerebrospinal fluid biomarker of Alzheimer's disease. [PDF]
Gómez de San José N +17 more
europepmc +1 more source

