Results 21 to 30 of about 69,061 (289)
Aquaporin-4 Expression in Meningioma Malignancy Progression
Brazilian Neurosurgery, 2023 Objectives The aim of the present study is to analyze if aquaporin-4 (AQP4) may also be a tumor progression marker for meningiomas. Methods This is an immunohistochemistry study realized at the Universidade de São Paulo, São Paulo, state of ...
Benedito Jamilson Araújo Pereira +5 more
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Neuromyelitis optica spectrum disorders with an inverted V sign on spinal cord magnetic resonance imaging: antiaquaporin-4 antibody and functional vitamin B12 deficiency [PDF]
Journal of Medicine and Life Science, 2022 Several studies have reported a possible link between antiaquaporin- 4 antibody and vitamin B12 deficiency in neuromyelitis optica spectrum disorder (NMOSD).
Sung Jo Bang +4 more
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Aquaporin 4 and neuromyelitis optica [PDF]
The Lancet Neurology, 2012 Neuromyelitis optica is an inflammatory demyelinating disorder of the CNS. The discovery of circulating IgG1 antibodies against the astrocyte water channel protein aquaporin 4 (AQP4) and the evidence that AQP4-IgG is involved in the development of neuromyelitis optica revolutionised our understanding of the disease.
Marios C, Papadopoulos, A S, Verkman
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The Role of Aquaporins in Spinal Cord Injury
Cells, 2023 Edema formation following traumatic spinal cord injury (SCI) exacerbates secondary injury, and the severity of edema correlates with worse neurological outcome in human patients. To date, there are no effective treatments to directly resolve edema within
Terese A. Garcia +2 more
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Bisacodyl overcomes morphine-induced constipation by decreasing colonic Aquaporin-3 and Aquaporin-4 expression [PDF]
Research Results in Pharmacology, 2022 Introduction: Morphine is an opioid prescribed to treat aches and pains. However, morphine often causes opioid-induced constipation (OIC). Aquaporin (AQP) transporters, especially AQP3 and AQP4, play an essential role in mediating constipation. Bisacodyl
Mahardian Rahmadi +9 more
doaj +3 more sources
Rinsho Shinkeigaku, 2008 In human body, there are thirteen water channels but their expression patterns are tissue specific. Aquaporin-4 (AQP4) is a predominantly expressed water channel in the mammalian brain and an important drug target for treatment of cerebral edema, bipolar disorder, and mesial temporal lobe epilepsy.
Kazutoshi, Tani +2 more
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Aquaporin 4 as a NH3 Channel [PDF]
Journal of Biological Chemistry, 2016 Ammonia is a biologically potent molecule, and the regulation of ammonia levels in the mammalian body is, therefore, strictly controlled. The molecular paths of ammonia permeation across plasma membranes remain ill-defined, but the structural similarity of water and NH3 has pointed to the aquaporins as putative NH3-permeable pores. Accordingly, a range
Assentoft, Mette +5 more
openaire +5 more sources
AER-270 and TGN-020 are not aquaporin-4 water channel blockers [PDF]
Unger L +19 more
europepmc +2 more sources
Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]
, 2015 To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Asgari, Nasrin +4 more
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Fatal anti-aquaporin-4 seropositive neuromyelitis optica spectrum disorder in tuberculosis [PDF]
, 2014 © 2014 Sridhar et al.; licensee BioMed Central Ltd.Background: Neuromyelitis optica (NMO) is an autoimmune inflammatory condition of the central nervous system that is characterized by circulating anti-aquaporin-4 antibodies, transverse myelitis and ...
Chan, JFW, Sridhar, S, Yuen, KY
core +1 more source