Results 11 to 20 of about 478 (150)
A Spotlight on Archaea in Humans, Livestock and Poultry: A Review [PDF]
Veterinary Medicine and ScienceThe microbiota includes prokaryotes (archaea and bacteria) and eukaryotes. Archaea are single‐celled prokaryotes and essential part of gut microbiome. Researches on archaea in ruminants and humans are more than mono‐gastric.
Ahmad Salahi, Wafaa A. Abd El‐Ghany
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Morphology, biophysical properties and protein-mediated fusion of archaeosomes. [PDF]
PLoS ONE, 2012 As variance from standard phospholipids of eubacteria and eukaryotes, archaebacterial diether phospholipids contain branched alcohol chains (phytanol) linked to glycerol exclusively with ether bonds.
Vid Šuštar +7 more
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Ultradeformable Archaeosomes for Needle Free Nanovaccination with Leishmania braziliensis Antigens. [PDF]
PLoS ONE, 2016 Total antigens from Leishmania braziliensis promastigotes, solubilized with sodium cholate (dsLp), were formulated within ultradeformable nanovesicles (dsLp-ultradeformable archaeosomes, (dsLp-UDA), and dsLp-ultradeformable liposomes (dsLp-UDL)) and ...
Leticia H Higa +9 more
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The potential of archaeosomes as carriers of pDNA into mammalian cells
Artificial Cells, Nanomedicine, and Biotechnology, 2015 This paper describes the formulation of archaeosomes and the evaluation of their abilities to facilitate in vitro DNA delivery. Lipids of the H.hispanica 2TK2 strain were used in archaeosome formation, which is formulated by mixing H.hispanica 2TK2 lipids with plasmid DNA encoding green fluorescent protein (GFP) or β-galactosidase (β-gal).
Turan, Kadir +3 more
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Archaeosomes as novel antigen delivery systems
FEMS Microbiology Letters, 1997 The humoral immune response mounted in BALB/c mice against bovine serum albumin or cholera toxin B subunit was compared when the antigens were associated with liposomes composed of either archaeal ether lipids or conventional lipids. Antibody titres in sera from mice immunised intraperitoneally were elevated to an extent comparable to those achieved ...
Sprott, G., Tolson, D., Patel, G.
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Ultradeformable archaeosomes as new topical adjuvants [PDF]
Nanomedicine: Nanotechnology, Biology and Medicine, 2012 Ultradeformable archaeosomes (UDA) are vesicles made of soybean phosphatidylcholine (SPC), sodium cholate (NaChol) and polar lipids from Halorubrum tebenquichense (3:1:3 wt/wt). Although ultradeformable liposomes (UDL, made of SPC and NaChol at 6:1 wt/wt) and UDA were neither captured nor caused cytotoxicity on keratinocytes, UDA was avidly captured by
Higa, Leticia Herminia +6 more
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Archaeosomes and Tetraether Lipid Liposome
Pharmaceutical Sciences and Research, 2012 Archaea have phytanyl ether lipids which is one of the characteristics that separates them from bacteria and eukaryotes. Some archaea have also unique membrane spanning tetrae- ther lipids (T EL); in Sulfolobus and Ihermoplasma species these TELmake up the majority of total membrane lipids.
Freisleben, H. (Hans-Joachim)
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Adjuvanted Schistosoma mansoni-Cathepsin B With Sulfated Lactosyl Archaeol Archaeosomes or AddaVax™ Provides Protection in a Pre-Clinical Schistosomiasis Model [PDF]
Frontiers in Immunology, 2020 Schistosomiasis threatens 800 million people worldwide. Chronic pathology manifests as hepatosplenomegaly, and intestinal schistosomiasis caused by Schistosoma mansoni can lead to liver fibrosis, cirrhosis, and blood in the stool.
Dilhan J. Perera +12 more
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Archaeosomes as Drug and Vaccine Nanodelivery Systems
, 2006 Archaeosomes, liposomes made from the polar lipids extracted from the membranes of Archaea, have been extensively studied for potential applications in drug and vaccine delivery over the past decade only. Archaeosomes offer significant advantages as nanodelivery vesicles over conventional liposomes made from the ester lipids found in Eukarya and ...
Patel, G., Chen, W.
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Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Advanced NanoBiomed ResearchThe growing concerns regarding the immunogenicity of polyethylene glycol (PEG) have prompted the search for alternative excipients that can prolong circulation in parenteral drug delivery.
Viktor Sedlmayr +9 more
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