Results 41 to 50 of about 1,749 (159)

Effects of arctigenin on RANKL-induced signaling in BMMs.

, 2014
(A) Effects of arctigenin on the expression of osteoclast-related genes. BMMs were cultured in the presence of RANKL and M-CSF together with or without 1 µM arctigenin.
Shigetoshi Kadota (510441), Hiroyasu Esumi (392822), Naoyuki Takahashi (937), Feng Li (30515), Yasuhiro Kobayashi (510442), Nobuyuki Udagawa (934), Shunsuke Uehara (510440), Teruhito Yamashita (510439)   +7 more
core   +1 more source

Image_1_28-Day Oral Chronic Toxicity Study of Arctigenin in Rats.TIF

, 2018
Arctium lappa (burdock) is the most popular daily edible vegetable in China and Japan because of its general health tonic effects. Previous studies focused on the beneficial role of Arctigenin but neglected its potential side-effects and toxicities.
Yuan-yuan Lv (5792930), Xin Li (51274), Jing-chun Yao (5792933), Bin Li (39349), Lan-fang Li (5792921), Gui-min Zhang (5792936), Jian Yang (12136), Ming-zhi Wang (5792927), Yu-jun Tan (5792915), Yu-shan Ren (5792918), Li-juan Cui (5792924), Zhong Liu (288945), Lei Gao (6566), Jie Li (15030), Xiao-li Xu (1893739)   +14 more
core   +1 more source

Arctigenin and biochanin A impact on MDA-MB-231 breast cancer cells: In silico and in vitro analysis [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Breast cancer remains a leading cause of mortality among women, with triple-negative breast cancer (TNBC) being particularly aggressive. Phytoestrogens have shown potential as anti-cancer agents by reducing cancer cell viability and promoting ...
Ade Arsianti, Miftahul Khair Akbar, Linda Erlina   +2 more
doaj   +1 more source

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives

Brain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi, Md Abul Hassan, Md. Al Amin, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Ramenani Hari Babu, Pericharla Venkata Narasimha Raju, Krishna Vamsi Kandimalla, Phanindra Erukulla, Patibandla Jahnavi, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, Safia Obaidur Rab, Sharuk L. Khan   +13 more
wiley   +1 more source

Table_2_28-Day Oral Chronic Toxicity Study of Arctigenin in Rats.DOCX

, 2018
Arctium lappa (burdock) is the most popular daily edible vegetable in China and Japan because of its general health tonic effects. Previous studies focused on the beneficial role of Arctigenin but neglected its potential side-effects and toxicities.
Yuan-yuan Lv (5792930), Xin Li (51274), Jing-chun Yao (5792933), Bin Li (39349), Lan-fang Li (5792921), Gui-min Zhang (5792936), Jian Yang (12136), Ming-zhi Wang (5792927), Yu-jun Tan (5792915), Yu-shan Ren (5792918), Li-juan Cui (5792924), Zhong Liu (288945), Lei Gao (6566), Jie Li (15030), Xiao-li Xu (1893739)   +14 more
core   +1 more source

Cinnamaldehyde From Cinnamon as a Food‐Derived Bioactive: Phytochemistry, Anticancer Mechanisms, Bioavailability, Nanoformulation and Safety

Food Frontiers, Volume 7, Issue 5, September 2026.
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi, Sally Kamau, Gulnaz Seitimova, Shynar Zhumagaliyeva, Javad Sharifi‐Rad, William N. Setzer, Daniela Calina   +6 more
wiley   +1 more source

Image_3_28-Day Oral Chronic Toxicity Study of Arctigenin in Rats.TIF

, 2018
Arctium lappa (burdock) is the most popular daily edible vegetable in China and Japan because of its general health tonic effects. Previous studies focused on the beneficial role of Arctigenin but neglected its potential side-effects and toxicities.
Yuan-yuan Lv (5792930), Xin Li (51274), Jing-chun Yao (5792933), Bin Li (39349), Lan-fang Li (5792921), Gui-min Zhang (5792936), Jian Yang (12136), Ming-zhi Wang (5792927), Yu-jun Tan (5792915), Yu-shan Ren (5792918), Li-juan Cui (5792924), Zhong Liu (288945), Lei Gao (6566), Jie Li (15030), Xiao-li Xu (1893739)   +14 more
core   +1 more source

Arctigenin inhibits prostate tumor growth in high-fat diet fed mice through dual actions on adipose tissue and tumor [PDF]

, 2020
This study investigated the inhibitory effect of arctigenin, a novel anti-inflammatory lignan, on prostate cancer in obese conditions both in vitro and in vivo. In vitro obese models were established by co-culture of mouse adipocytes 3T3-L1 with androgen-
Diaz, Tanya, Henning, Susanne M, Wang, Piwen, Magyar, Clara E, Hao, Qiongyu, Verduzco, Alejandro del Rio, Vadgama, Jaydutt V, Rettig, Matthew B, Zhong, Jin, Elshimali, Yahya   +9 more
core   +1 more source

Emetine and Its Derivatives as Anticancer Agents Targeting the PI3K/AKT/mTOR Pathway: A Narrative Review of Mechanisms, Pharmacology, and Clinical Insights

Journal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT Emetine (EMT), a naturally occurring tetrahydroisoquinoline alkaloid, shows diverse biological actions, including anticancer effects. Despite existing studies, the role of EMT derivatives in cancer, particularly in relation to the PI3K/AKT/mTOR signalling pathway, remains largely underexplored.
Mst. Ismatara Khatun, Samy Selim, Asif Hassan Malik, Md. Sakib Al Hasan, Abul Bashar Ripon Khalipha, Noshin Tasnim Yana, Mohammad Y. Alshahrani, Md. Arif Hossain, Imam Hossen Rakib, Anike Chakrabarty, Emon Mia   +10 more
wiley   +1 more source

Novel strategy for treatment of Japanese encephalitis using arctigenin, a plant lignan

, 2008
Objectives To evaluate therapeutic efficacy of arctigenin in an experimental model of Japanese encephalitis (JE). Methods Four- to 5-week-old BALB/c mice of either sex were infected intravenously with lethal dose of 3 × 105 pfu of Japanese ...
Swarup, V., Mishra, M. K., Basu, A., Ghosh, J.   +3 more
core   +1 more source