Results 51 to 60 of about 1,749 (159)

Molecular Docking Analysis of Arctigenin and Its Analogues against Cyclin- Dependent Kinases (CDKs) for the Treatment of Cancer

open access: yes, 2023
Arctigenin is a potent bioactive compound synthesized from Arctium lappa that has proved its activity against different cancer cell lines. "The motive of this study is to analyze the potent pharmacological properties of Arctigenin and its derivatives ...
Md. Shimul Bhuia (16668210)
core   +1 more source

Anti‐inflammatory activity of arctigenin against PCV2 infection in a mouse model

open access: yesVeterinary Medicine and Science, 2022
Arctigenin (ACT) is a novel anti‐inflammatory lignan extracted from Arctium lappa L, a herb commonly used in traditional Chinese herbal medicine.
Lijun Wu   +7 more
doaj   +1 more source

Phytotherapeutic Regulation of Matrix Metalloproteinases in Diabetic Foot Ulcer: Molecular Mechanisms and Wound Healing Perspectives

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Chronic inflammation in diabetic foot ulcers elevates MMP activity and suppresses TIMP and growth factor signaling, impairing tissue repair. Phytochemicals modulate NF‐κB/MAPK pathways and enhance Nrf2–TIMP expression, restoring MMP/TIMP balance, promoting collagen deposition, angiogenesis, and re‐epithelialization, leading to effective wound healing ...
Vishnu Priyan Elaiyaraja   +3 more
wiley   +1 more source

Quantitative Proteomic Analysis Reveals That Arctigenin Alleviates Concanavalin A-Induced Hepatitis Through Suppressing Immune System and Regulating Autophagy

open access: yesFrontiers in Immunology, 2018
Concanavalin A-induced autoimmune hepatitis is a well-established experimental model for immune-mediated liver injury. It has been widely used in the therapeutic studies of immune hepatitis. The in-depth analysis of dysregulated proteins from comparative
Qin Feng   +13 more
doaj   +1 more source

Table_1_28-Day Oral Chronic Toxicity Study of Arctigenin in Rats.DOCX

open access: yes, 2018
Arctium lappa (burdock) is the most popular daily edible vegetable in China and Japan because of its general health tonic effects. Previous studies focused on the beneficial role of Arctigenin but neglected its potential side-effects and toxicities.
Yuan-yuan Lv (5792930)   +14 more
core   +1 more source

Table1_Serial five-membered lactone ring ions in the treatment of Alzheimer’s diseases-comprehensive profiling of arctigenin metabolites and network analysis.docx

open access: yes, 2022
Arctigenin is a phenylpropanoid dibenzylbutyro lactone lignan compound with multiple biological functions. Previous studies have shown that arctigenin have neuroprotective effects in Alzheimer’s disease (AD) models both in vivo and in vitro; however, its
Qiyan Li (12472278)   +8 more
core   +1 more source

Image_2_28-Day Oral Chronic Toxicity Study of Arctigenin in Rats.TIF

open access: yes, 2018
Arctium lappa (burdock) is the most popular daily edible vegetable in China and Japan because of its general health tonic effects. Previous studies focused on the beneficial role of Arctigenin but neglected its potential side-effects and toxicities.
Yuan-yuan Lv (5792930)   +14 more
core   +1 more source

Sample Preparation and Separation of Lignans by Liquid Chromatography

open access: yesJournal of Separation Science, Volume 49, Issue 5, May 2026.
ABSTRACT Lignans are important phytochemicals found mostly in the resins of coniferous trees, but are also introduced into human diets through foods such as sesame seeds and extra‐virgin olive oil. They are pharmacologically interesting mainly because of their antioxidant activities, and they have also been shown to have cytotoxic and antimicrobial ...
Miikka Paloluoto, Susanne K. Wiedmer
wiley   +1 more source

CAR‐T Cells: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 5, May 2026.
This graphical abstract outlines the current status, challenges, and future prospects of CAR‐T cells. The biological basis of CAR‐T cell therapy is the elegant redirection of adaptive immunity. Its initial successes have exposed a landscape of multifaceted challenges.
Aya Sedky Adly   +6 more
wiley   +1 more source

DataSheet_1_Toxicity Study of 28-Day Subcutaneous Injection of Arctigenin in Beagle Dogs.docx

open access: yes, 2019
Our previous studies have investigated the systematic pharmacokinetic characteristics, biological activities, and toxicity of arctigenin. In this research, the potential toxicities of arctigenin in beagle dogs were investigated via repeated 28-day ...
Li-hong Pan (7506596)   +9 more
core   +1 more source

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