Results 71 to 80 of about 1,749 (159)

Mechanistic insights into selective killing of OXPHOS-dependent pancreatic cancer cells by arctigenin

, 2016
Arctigenin has previously been identified as a potential anti-tumor treatment for advanced pancreatic cancer. However, the mechanism of how arctigenin kills cancer cells is not fully understood.
Riebel, Virginie, Chibout, Salah-Dine, Uteng, Marianne, Wolf, Armin, Brecht, Karin, Couttet, Philippe, Paech, Franziska, Pognan, Francois, Krähenbühl, Stephan   +8 more
core   +1 more source

Identification of Anti‐Inflammatory and Analgesic Mechanisms of Naru‐3 Wei Pill Using Animal Models, UHPLC‐QE‐MS, and Integrated Network Pharmacology

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Naru‐3 Wei Pill is a traditional Mongolian Medicine (TMM) that has anti‐inflammatory, analgesic, and antibacterial effects. The present study aimed to demonstrate the anti‐inflammatory and analgesic effect of Naru‐3 Wei Pill, identify the core components and key targets and determine the pharmacological basis and mechanism of its blood‐borne
Zhiqiang Han, Husile Kang, Aidi Zhang, Qigeqin, Baolechaolu, Wulanqiqige, Huan Wang, Yanhua Xu, HaSi, Anda, Lan Xue, K. Sony Reddy   +11 more
wiley   +1 more source

Abstract 5253: Arctigenin inhibits prostate tumor growth in vitro and in vivo in obese state

, 2017
Arctigenin is a novel anti-inflammatory lignan derived mainly from the seeds of Arctium lappa which is an herb widely used in traditional Chinese medicine to treat inflammation related diseases.
Tanya Diaz, Jaydutt Vadgama, Susanne Henning, Piwen Wang   +3 more
core   +1 more source

Neuroprotective Effects of an Aqueous Extract of Forsythia viridissima and Its Major Constituents on Oxaliplatin-Induced Peripheral Neuropathy

Molecules, 2019
The dried fruits of Forsythia viridissima have been prescribed to relive fever, pain, vomiting, and nausea in traditional medicine. Oxaliplatin (LOHP) is used to treat advanced colorectal cancer; however, it frequently induces peripheral neuropathies ...
Jin-Mu Yi, Sarah Shin, No Soo Kim, Ok-Sun Bang   +3 more
doaj   +1 more source

Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Jialu Zhang, Yuqian Liu, Shuying Ren, Zhouyuan Wang, Yunxia Li, Lianci Peng, Rendong Fang, Jianchao Wei   +7 more
wiley   +1 more source

Oxidative phosphorylation at the crossroads of cancer: Metabolic orchestration, stromal collusion, and emerging therapeutic horizons

Interdisciplinary Medicine, Volume 3, Issue 6, November 2025.
Although most cancer cells rely on aerobic glycolysis, Oxidative phosphorylation (OXPHOS) remains essential for their survival, proliferation, and metastasis. With the emergence of OXPHOS‐targeted drugs, its therapeutic potential is becoming increasingly evident.
Keke Chen, Bo Wang, Hongying Shu, Jianxin Lyu, Wei Cui, Hezhi Fang   +5 more
wiley   +1 more source

Effect of arctigenin on osteoclast-like cell formation in the co-culture with osteoblastic cells.

, 2014
(A) Effects of arctigenin and CsA on osteoclast-like cell formation in the co-culture. Osteoblastic cells and bone marrow cells were co-cultured in the presence of 1α,25(OH)2D3 together with or without 1 µM arctigenin or 1 µg/mL CsA.
Shigetoshi Kadota (510441), Hiroyasu Esumi (392822), Naoyuki Takahashi (937), Feng Li (30515), Yasuhiro Kobayashi (510442), Nobuyuki Udagawa (934), Shunsuke Uehara (510440), Teruhito Yamashita (510439)   +7 more
core   +1 more source

Isolation and Characterization of Bioactive Compounds from Scotch Thistle (Onopordum acanthium L.) Seeds [PDF]

Pharmaceutical Sciences
Background: Scotch thistle (Onopordum acanthium L.) is a medicinal food plant known for its phytochemical diversity. Methods: In this study, methanolic and petroleum ether extracts of Scotch thistle seeds were subjected to phytochemical analysis.
Sakineh Mohammadi, Ali Movefeghi, Abbas Delazar, Sanaz Hamedeyazdan, Mir Babak Bahadori, Hossein Nazemiyeh   +5 more
doaj   +1 more source

Arctigenin Reduces Myofibroblast Activities in Oral Submucous Fibrosis by LINC00974 Inhibition

, 2019
Oral submucous fibrosis (OSF) is an oral precancerous condition associated with the habit of areca nut chewing and the TGF-β pathway. Currently, there is no curative treatment to completely heal OSF, and it is imperative to alleviate patients’
Ching-Yeh Lin, Cheng-Chia Yu, Yi-Wen Liao, Pei-Ling Hsieh, Chih-Yu Peng, Ming-Yi Lu   +5 more
core   +1 more source

Effects of arctigenin on the nuclear translocation and activation of NFATc1.

, 2014
(A) Effects of arctigenin and CsA on the nuclear translocation of NFATc1 and NF-κB in osteoclast-like cells. Purified osteoclast-like cells were cultured for 16 h in the absence of RANKL.
Shigetoshi Kadota (510441), Hiroyasu Esumi (392822), Naoyuki Takahashi (937), Feng Li (30515), Yasuhiro Kobayashi (510442), Nobuyuki Udagawa (934), Shunsuke Uehara (510440), Teruhito Yamashita (510439)   +7 more
core   +1 more source