Results 11 to 20 of about 23,715 (250)

Galanin Receptor-Mediated Inhibition of Glutamate Release in the Arcuate Nucleus of the Hypothalamus [PDF]

The Journal of Neuroscience, 1998
It is thought that galanin, a 29 amino acid neuropeptide, is involved in various neuronal functions, including the regulation of food intake and hormone release. Consistent with this idea, galanin receptors have been demonstrated throughout the brain, with high levels being observed in the hypothalamus.
G A, Kinney, P J, Emmerson, R J, Miller
semanticscholar   +4 more sources

Mapping neuronal inputs to Kiss1 neurons in the arcuate nucleus of the mouse.

PLoS ONE, 2019
The normal function of the mammalian reproductive axis is strongly influenced by physiological, metabolic and environmental factors. Kisspeptin neuropeptides, encoded by the Kiss1 gene, are potent regulators of the mammalian reproductive axis by ...
Shel-Hwa Yeo, Victoria Kyle, Clemence Blouet, Susan Jones, William Henry Colledge   +4 more
doaj   +4 more sources

mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol [PDF]

Journal of Endocrinology, 2018
Current evidence suggests that estradiol (E2), the main ovarian steroid, modulates energy balance by regulating both feeding and energy expenditure at the central level, through the energy sensor AMP-activated protein kinase (AMPK). We hypothesized that the hypothalamic mechanistic target of rapamycin (mTOR) pathway, a well-established nutrient sensor ...
González-García, Ismael, Martinez de Morentin, Pablo B, Estévez-Salguero, Ánxela, Contreras, Cristina, Romero-Picó , Amparo, Fernø, Johan, Nogueiras, Ruben, Diéguez, Carlos, Tena-Sempere, Manuel, Tovar, Sulay, López, Miguel   +10 more
openaire   +6 more sources

Kisspeptin Neurons in the Arcuate Nucleus of the Hypothalamus Orchestrate Circadian Rhythms and Metabolism [PDF]

Current Biology, 2019
Successful reproduction in female mammals is precisely timed and must be able to withstand the metabolic demand of pregnancy and lactation. We show that kisspeptin-expressing neurons in the arcuate hypothalamus (Kiss1ARH) of female mice control the daily timing of food intake, along with the circadian regulation of locomotor activity, sleep, and core ...
Stephanie L, Padilla, Jazmine G, Perez, Miriam, Ben-Hamo, Christopher W, Johnson, Raymond E A, Sanchez, Ivana L, Bussi, Richard D, Palmiter, Horacio O, de la Iglesia   +7 more
openaire   +3 more sources

Cardiovascular Regulation by the Arcuate Nucleus of the Hypothalamus [PDF]

Hypertension, 2016
The importance of the central nervous system in cardiovascular regulation is well established.1,2 The brain is able to sense changes that occur in the peripheral circulation through several mechanisms, including afferent neural reflexes and humoral signals.
K. Rahmouni
openaire   +3 more sources

Ultraviolet B stimulates proopiomelanocortin signalling in the arcuate nucleus of the hypothalamus in mice [PDF]

Experimental Dermatology, 2016
AbstractWe previously found that ultraviolet B (UVB) could stimulate the paraventricular nucleus (PVN) with activation the systemic hypothalamic–pituitary– adrenal (HPA) axis. To investigate whether UVB can also stimulate other hypothalamic nuclei, we tested its effect on the proopiomelanocortin (POMC) related signalling system in the arcuate nucleus ...
Cezary, Skobowiat, Andrzej T, Slominski
openaire   +3 more sources

Endogenous amylin contributes to birth of microglial cells in arcuate nucleus of hypothalamus and area postrema during fetal development.

American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2019
Amylin acts in the area postrema (AP) and arcuate nucleus (ARC) to control food intake. Amylin also increases axonal fiber outgrowth from the AP→nucleus tractus solitarius and from ARC→hypothalamic paraventricular nucleus. More recently, exogenous amylin
T. Lutz, Christelle Le Foll
semanticscholar   +2 more sources

A critical period for the trophic actions of leptin on AgRP neurons in the arcuate nucleus of the hypothalamus [PDF]

Journal of Comparative Neurology, 2017
AbstractIn the developing hypothalamus, the fat‐derived hormone leptin stimulates the growth of axons from the arcuate nucleus of the hypothalamus (ARH) to other regions that control energy balance. These projections are significantly reduced in leptin deficient (Lepob/ob) mice and this phenotype is largely rescued by neonatal leptin treatments ...
Anna Kamitakahara, Karine Bouyer, Chien‐Hua Wang, Richard Simerly   +3 more
openaire   +3 more sources

Leptin Modulates the Intrinsic Excitability of AgRP/NPY Neurons in the Arcuate Nucleus of the Hypothalamus [PDF]

The Journal of Neuroscience, 2014
The hypothalamic arcuate nucleus (ARH) is a brain region critical for regulation of food intake and a primary area for the action of leptin in the CNS. In lean mice, the adipokine leptin inhibits neuropeptide Y (NPY) and agouti-related peptide (AgRP) neuronal activity, resulting in decreased food intake.
Scott B, Baver, Kevin, Hope, Shannon, Guyot, Christian, Bjørbaek, Catherine, Kaczorowski, Kristen M S, O'Connell   +5 more
openaire   +3 more sources

Conditional Deletion of the Prolactin Receptor Reveals Functional Subpopulations of Dopamine Neurons in the Arcuate Nucleus of the Hypothalamus [PDF]

Journal of Neuroscience, 2016
UNLABELLED: Tuberoinfundibular dopamine (TIDA) neurons, known as neuroendocrine regulators of prolactin secretion from the pituitary gland, also release GABA within the hypothalamic arcuate nucleus.
R. Brown, I. Kokay, Hollian R Phillipps, S. Yip, Papillon Gustafson, Amanda Wyatt, C. Larsen, P. Knowles, S. R. Ladyman, P. LeTissier, D. Grattan   +10 more
semanticscholar   +2 more sources