Results 31 to 40 of about 23,715 (250)

The hypothalamus as the central regulator of energy balance and its impact on current and future obesity treatments [PDF]

Archives of Endocrinology and Metabolism
The hypothalamus is a master regulator of energy balance in the body. First-order hypothalamic neurons localized in the arcuate nucleus sense systemic signals that indicate the energy stores in the body.
Bruna Bombassaro, Eliana P. Araujo, Licio A. Velloso   +2 more
doaj   +1 more source

Control by the brain of vitamin A homeostasis

iScience, 2023
Summary: Vitamin A is a micronutrient essential for vertebrate animals maintained in homeostatic balance in the body; however, little is known about the control of this balance.
Peter I. Imoesi, Cristian M. Olarte-Sánchez, Lorenzo Croce, William S. Blaner, Peter J. Morgan, Lora Heisler, Peter McCaffery   +6 more
doaj   +1 more source

Chronic high-fat diet induces overeating and impairs synaptic transmission in feeding-related brain regions

Frontiers in Molecular Neuroscience, 2022
Obesity is linked to overeating, which can exacerbate unhealthy weight gain. However, the mechanisms for mediating such linkages are elusive. In the current study, we hypothesized that synaptic remodeling occurs in feeding-related brain regions of obese ...
Xu Wang, Xu Wang, Haohong Li, Haohong Li
doaj   +1 more source

Neural correlates underlying naloxone-induced amelioration of sexual behavior deterioration due to an alarm pheromone

Frontiers in Neuroscience, 2015
Sexual behavior is suppressed by various types of stressors. We previously demonstrated that an alarm pheromone released by stressed male Wistar rats is a stressor to other rats, increases the number of mounts needed for ejaculation, and decreases the ...
Tatsuya eKobayashi, Yasushi eKiyokawa, Yukari eTakeuchi, Yuji eMori   +3 more
doaj   +1 more source

alpha-Tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors [PDF]

, 2013
Peer ...
Briancon, N, Robins, S.C., Taylor, V, Maratos-Flier, E., Giachino, C., McNay, D.E., Taylor, V., Placzek, M., Flier, J. S., Robins, SC, Stewart, I., Robins, S. C., Maratos-Flier, E, Götz, M., Ninkovic, J, McNay, D. E., Goetz, M., Placzek, M, Giachino, C, Kokoeva, M V, Goetz, M, Flier, J.S., Kokoeva, M.V., Flier, J S, Kokoeva, M. V., Kokoeva, MV, Robins, S C, Stewart, I, Flier, JS, Briancon, N., McNay, D E, Ninkovic, J., Mcnay, DE   +32 more
core   +1 more source

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Nature Communications, 2018
In the hypothalamus, the arcuate nucleus (ARC) contains AgRP-neurons that regulate energy balance as well as GHRH-neurons that regulate linear growth. Here, the authors looked at how the transcription factors Dlx1/2 and Otp link development of AgRP- and ...
Bora Lee, Janghyun Kim, Taekyeong An, Sangsoo Kim, Esha M. Patel, Jacob Raber, Soo-Kyung Lee, Seunghee Lee, Jae W. Lee   +8 more
doaj   +1 more source

Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes

eLife, 2022
Proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus are essential to regulate food intake and energy balance. However, the ontogenetic transcriptional programs that specify the identity and functioning of these neurons are poorly ...
Hui Yu, Marcelo Rubinstein, Malcolm J Low   +2 more
doaj   +1 more source

Formation of Projection Pathways from the Arcuate Nucleus of the Hypothalamus to Hypothalamic Regions Implicated in the Neural Control of Feeding Behavior in Mice

Journal of Neuroscience, 2004
The arcuate nucleus of the hypothalamus (ARH) is a critical component of forebrain pathways that regulate a variety of neuroendocrine functions, including an important role in relaying leptin signals to other parts of the hypothalamus.
S. Bouret, Shin J. Draper, R. Simerly
semanticscholar   +1 more source

Investigating the role of arcuate nucleus and paraventricular nucleus glucokinase in glucose homeostasis [PDF]

, 2020
The brain is as an important regulator of appetite and metabolism. Glucokinase (GK) is a key component of glucose sensing, and is expressed in many glucose sensitive neurones (Rosario et al., 2016, Pocai et al., 2005b).
Ratnasabapathy, Risheka
core   +1 more source

Long-term effects of sleep deprivation on neuronal activity in four hypothalamic areas

Neurobiology of Disease, 2018
Lack of adequate sleep has become increasingly common in our 24/7 society. Unfortunately diminished sleep has significant health consequences including metabolic and cardiovascular disease and mental disorders including depression.
Karim Fifel, Johanna H. Meijer, Tom Deboer   +2 more
doaj   +1 more source