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Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate [PDF]

open access: goldIUCrJ, 2022
Arenaviruses are emerging enveloped negative-sense RNA viruses that cause neurological and hemorrhagic diseases in humans. Currently, no FDA-approved vaccine or therapeutic agent is available except for ribavirin, which must be administered early during ...
Thi Hong Van Nguyen   +5 more
doaj   +7 more sources

Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein [PDF]

open access: goldViruses, 2020
Arenaviridae is a family of viruses harbouring important emerging pathogens belonging to the Bunyavirales order. Like in other segmented negative strand RNA viruses, the nucleoprotein (NP) is a major actor of the viral life cycle being both (i) the ...
Nicolas Papageorgiou   +8 more
doaj   +8 more sources

ICTV Virus Taxonomy Profile: Arenaviridae 2023. [PDF]

open access: hybridJ Gen Virol, 2023
Arenaviridae is a family for ambisense RNA viruses with genomes of about 10.5 kb that infect mammals, snakes, and fish. The arenavirid genome consists of two or three single-stranded RNA segments and encodes a nucleoprotein (NP), a glycoprotein (GP) and ...
Radoshitzky SR   +12 more
europepmc   +9 more sources

Novel relatives of Mecsek Mountains mammarenavirus (family Arenaviridae) in hedgehogs living in different sampling areas in Hungary [PDF]

open access: goldScientific Reports
Mammarenaviruses (genus Mammarenavirus, family Arenaviridae) are rodent-borne zoonotic viruses consisting of 52 viral species, including ten that are pathogenic to humans.
Károly Takáts   +5 more
doaj   +5 more sources

Aporé virus, a novel mammarenavirus (Bunyavirales: Arenaviridae) related to highly pathogenic virus from South America [PDF]

open access: diamondMemorias do Instituto Oswaldo Cruz, 2019
Here, we report the complete genome sequence of the Aporé virus (Bunyavirales: Arenaviridae), obtained from a wild rodent Oligoryzomys mattogrossae captured in Mato Grosso do Sul state, Brazil.
Jorlan Fernandes   +6 more
doaj   +3 more sources

Virus Arenaviridae y Fiebres Hemorrágicas: Una Revisión

open access: diamondRevista Científica de Enfermería UNITEPC, 2023
Introducción: Los arenavirus, pertenecientes a la familia Arenaviridae, pueden provocar fiebre hemorrágica, una enfermedad grave. Debido a brotes esporádicos y la falta de conocimiento en áreas críticas, la investigación de estos virus es esencial para ...
Juan de Dios Mogro Lujan   +1 more
semanticscholar   +4 more sources

Combination of highly antigenic nucleoproteins to inaugurate a cross-reactive next generation vaccine candidate against Arenaviridae family [PDF]

open access: goldHeliyon, 2021
Arenaviral infections often result lethal hemorrhagic fevers, affecting primarily in African and South American regions. To date, there is no FDA-approved licensed vaccine against arenaviruses and treatments have been limited to supportive therapy. Hence,
Kazi Faizul Azim   +6 more
doaj   +3 more sources

Characterization of Haartman Institute snake virus-1 (HISV-1) and HISV-like viruses-The representatives of genus Hartmanivirus, family Arenaviridae.

open access: goldPLoS Pathogens, 2018
The family Arenaviridae comprises three genera, Mammarenavirus, Reptarenavirus and the most recently added Hartmanivirus. Arenaviruses have a bisegmented genome with ambisense coding strategy.
Jussi Hepojoki   +10 more
doaj   +4 more sources

A novel mammarenavirus (family Arenaviridae) in hedgehogs (Erinaceus roumanicus) in Europe [PDF]

open access: hybridArchives of Virology, 2023
In this study, a novel mammarenavirus (family Arenaviridae) was identified in a hedgehog (family Erinaceidae) in Hungary and genetically characterized.
G. Reuter   +4 more
semanticscholar   +4 more sources

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