Développement d'un Test Sérologique Contre le Virus de la Chorioméningite Lymphocytaire [PDF]
Les Arenavirus sont une famille de virus à ARN très diversifiée avec plus de 23 espèces recensées dans le monde, divisées en deux Clades majeures (Emonet et al., 2009).
Schaffner, D.
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Rodents and risk in the Mekong delta of Vietnam: seroprevalence of selected zoonotic viruses in rodents and humans [PDF]
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Baker, Stephen +19 more
core +1 more source
Viral Live‐Attenuated Vaccines (LAVs): Past and Future Directions
Live attenuated vaccines represent a delicate equilibrium between virulence and immunogenicity during adaptation. The process of animal adaptation involves artificial selection; therefore, adapted viruses exhibit decreased pathogenicity to their original hosts and increased pathogenicity to their adapted hosts.
Yan‐Dong Tang +3 more
wiley +1 more source
Sabiá Virus–Like Mammarenavirus in Patient with Fatal Hemorrhagic Fever, Brazil, 2020
New World arenaviruses can cause chronic infection in rodents and hemorrhagic fever in humans. We identified a Sabiá virus–like mammarenavirus in a patient with fatal hemorrhagic fever from São Paulo, Brazil.
Fernanda de Mello Malta +13 more
doaj +1 more source
Exploring the druggability of the UEV domain of human TSG101 in search for broad‐spectrum antivirals
Abstract The ubiquitin E2 variant domain of TSG101 (TSG101‐UEV) plays a pivotal role in protein sorting and virus budding by recognizing PTAP motifs within ubiquitinated proteins. Disruption of TSG101‐UEV/PTAP interactions has emerged as a promising strategy for the development of host‐oriented broad‐spectrum antivirals with low susceptibility to ...
Fernando Montero +17 more
wiley +1 more source
Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus. [PDF]
Intracellular events in the synthesis, glycosylation, and transport of the lymphocytic choriomeningitis virus (LCMV) glycoproteins have been examined. We have shown by N-glycanase digestion that LCMV strain Arm-4 bears five oligosaccharides on GP-1 and ...
Buchmeier, MJ +3 more
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Arbovirus infections and viral haemorrhagic fevers in Uganda : a serological survey in Karamoja district, 1984 [PDF]
Présentation des résultats de l'enquête effectuée sur 132 habitants du district de Karamoja en Ouganda, qui ont été examinés pour la recherche d'anticorps contre certains arbovirus dont la fièvre ...
Gonzalez, Jean-Paul +5 more
core +1 more source
Characterization of Junín arenavirus cell entry
Junín virus (JUNV) entry is conducted by receptor-mediated endocytosis. To explore the cellular entry mechanism of JUNV, inhibitory effects of drugs affecting the main endocytic pathways on JUNV entry into Vero cells were analysed. Compounds that impair clathrin-mediated endocytosis were shown to reduce virus internalization without affecting virion ...
M Guadalupe, Martinez +2 more
openaire +2 more sources
The figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
María del Carmen Villalobos‐Segura +3 more
wiley +1 more source
La schizophrénie touche aussi les enfants et les adolescents : une des modalités de leur prise en charge est assurée par le CTJA [Centre thérapeutique de jour pour adolescents] [PDF]
1% des schizophrénies se déclenchent avant l'âge de 10 ans. 20%, une sur cinq, commencent avant l'âge de 18 ans. Et dans 40% des cas de schizophrénie avérée, les premiers signes étaient apparus avant 18 ans.
Dunand, Fabien, Holzer, Laurent
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