Results 11 to 20 of about 7,989 (190)
Inhibition of Arenavirus Entry and Replication by the Cell-Intrinsic Restriction Factor ZMPSTE24 Is Enhanced by IFITM Antiviral Activity [PDF]
Frontiers in Microbiology, 2022 In the absence of effective vaccines and treatments, annual outbreaks of severe human haemorrhagic fever caused by arenaviruses, such as Lassa virus, continue to pose a significant human health threat.
Robert J. Stott-Marshall +1 more
doaj +3 more sources
Advances in Virology, 2011 Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions. On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus-host interactions
Shuzo Urata, Juan Carlos de la Torre
doaj +2 more sources
Emerging Infectious Diseases, 2011 To investigate arenavirus in Zambia, we characterized virus from the kidneys of 5 arenavirus RNA–positive rodents (Mastomys natalensis) among 263 captured.
Akihiro Ishii +8 more
doaj +2 more sources
Potent inhibition of arenavirus infection by a novel fusion inhibitor
Antiviral Research, 2021 Several arenaviruses, including Lassa and Lujo viruses in Africa and five New World arenavirus (NWA) species in the Americas, cause life-threatening viral hemorrhagic fevers.
Brian B Gowen +2 more
exaly +2 more sources
Arenavirus-Based Vectors Generate Robust SIV Immunity in Non-Human Primates
VaccinesArenavirus-based vectors are being investigated as therapeutic vaccine candidates with the potential to elicit robust CD8 T-cell responses. We compared the immunogenicity of replicating (artPICV and artLCMV) and non-replicating (rPICV and rLCMV ...
Bhawna Sharma +19 more
doaj +2 more sources
Infecciones por arenavirus [PDF]
Revista Mvz Cordoba, 2017 Los síndromes infecciosos asociados a arenavirus en América del sur son cuatro: síndrome febril de origen viral; fiebres hemorrágicas con o sin compromiso neurológico; meningitis asépticas y meningo-encefalitis. Entre los Arenavirus del nuevo mundo, está
Salim Mattar V +3 more
doaj +3 more sources
DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection.
PLoS Pathogens, 2018 Several arenaviruses cause hemorrhagic fever (HF) diseases that are associated with high morbidity and mortality in humans. Accordingly, HF arenaviruses have been listed as top-priority emerging diseases for which countermeasures are urgently needed ...
María Eugenia Loureiro +15 more
doaj +2 more sources
Mopeia Virus–related Arenavirus in Natal Multimammate Mice, Morogoro, Tanzania
Emerging Infectious Diseases, 2009 A serosurvey involving 2,520 small mammals from Tanzania identified a hot spot of arenavirus circulation in Morogoro. Molecular screening detected a new arenavirus in Natal multimammate mice (Mastomys natalensis), Morogoro virus, related to Mopeia virus.
Stephan Günther +12 more
doaj +2 more sources
Fiebres hemorrágicas por Arenavirus en Latinoamérica [PDF]
Salud Uninorte, 2010 Las fiebres hemorrágicas virales producidas por Arenavirus incluyen a los virus endémicos en África (Lassa) y el virus de la coriomeningitis linfocítica (LCMV), de distribución mundial, y los Arenavirus del Nuevo Mundo o Complejo Tacaribe, que incluye a ...
Ella Soto, Salim Mattar
doaj +4 more sources
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection. [PDF]
PLoS Pathogens, 2015 Arenaviruses such as Lassa virus (LASV) can cause severe hemorrhagic fever in humans. As a major impediment to vaccine development, delayed and weak neutralizing antibody (nAb) responses represent a unifying characteristic of both natural infection and ...
Rami Sommerstein +17 more
doaj +2 more sources