Results 41 to 50 of about 4,874 (174)
Arenavirus Concentration by Molecular Filtration [PDF]
Applied and Environmental Microbiology, 1977 Liter volumes of a human arenavirus pathogen (Machupo) and a nonpathogen (Tacaribe) were concentrated 30 to 100 times in less than 90 min without significant loss of particle infectivity.
J D, Gangemi +3 more
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A subpopulation of arenavirus nucleoprotein localizes to mitochondria [PDF]
Scientific Reports, 2021 AbstractViruses need cells for their replication and, therefore, ways to hijack cellular functions. Mitochondria play fundamental roles within the cell in metabolism, immunity and regulation of homeostasis due to which some viruses aim to alter mitochondrial functions.
Baggio, Francesca +4 more
openaire +5 more sources
Endangered wild salmon infected by newly discovered viruses
eLife, 2019 The collapse of iconic, keystone populations of sockeye (Oncorhynchus nerka) and Chinook (Oncorhynchus tshawytscha) salmon in the Northeast Pacific is of great concern. It is thought that infectious disease may contribute to declines, but little is known
Gideon J Mordecai +11 more
doaj +1 more source
The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion.
PLoS Pathogens, 2021 Arenavirus entry into host cells occurs through a low pH-dependent fusion with late endosomes that is mediated by the viral glycoprotein complex (GPC). The mechanisms of GPC-mediated membrane fusion and of virus targeting to late endosomes are not well ...
Ruben M Markosyan +4 more
doaj +1 more source
DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection.
PLoS Pathogens, 2018 Several arenaviruses cause hemorrhagic fever (HF) diseases that are associated with high morbidity and mortality in humans. Accordingly, HF arenaviruses have been listed as top-priority emerging diseases for which countermeasures are urgently needed ...
María Eugenia Loureiro +15 more
doaj +1 more source
Mopeia Virus–related Arenavirus in Natal Multimammate Mice, Morogoro, Tanzania
Emerging Infectious Diseases, 2009 A serosurvey involving 2,520 small mammals from Tanzania identified a hot spot of arenavirus circulation in Morogoro. Molecular screening detected a new arenavirus in Natal multimammate mice (Mastomys natalensis), Morogoro virus, related to Mopeia virus.
Stephan Günther +12 more
doaj +1 more source
Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform
Viruses, 2021 Lujo virus (LUJV), a highly pathogenic arenavirus, was first identified in 2008 in Zambia. To aid the identification of effective therapeutics for LUJV, we developed a recombinant reporter virus system, confirming reporter LUJV comparability with wild ...
Stephen R. Welch +9 more
doaj +1 more source
Infecciones por arenavirus [PDF]
Revista MVZ Córdoba, 2017 Los síndromes infecciosos asociados a arenavirus en América del sur son cuatro: síndrome febril de origen viral; fiebres hemorrágicas con o sin compromiso neurológico; meningitis asépticas y meningo-encefalitis. Entre los Arenavirus del nuevo mundo, está el complejo Tacaribe donde se encuentran los virus: Junín (Argentina), Guanarito (Venezuela ...
Salim Mattar V +3 more
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Frontiers in Microbiology, 2019 The majority of emerging and reemerging zoonotic viral pathogens are RNA viruses. Pathogen discovery programs of emerging infectious diseases (EIDs) in wildlife have implicated rodents and shrews as hosts of diverse human pathogens, such as hantaviruses,
Samson Omondi Onyuok +24 more
doaj +1 more source
Arenavirus research and antiviral candidate
Uirusu, 2018 Arenavirus is a genetic term for viruses belonging to the family Arenaviridae and is presented from lymphocytic choriomeningitis virus (LCMV), which shows almost no pathogenicity to humans, to Lassa virus, Junin virus, Machupo virus, Chapare virus, Lujo virus, Sabia virus, and Guanarito virus, which shows high pathogenicity to humans.
Hideki, Tani, Urata, Shuzo
openaire +3 more sources