Results 41 to 50 of about 7,989 (190)

Presence of Arenavirus in Mus musculus, Chiapas, Mexico

, 2023
En junio de 1967, en el estado de Chiapas, ocurrió un brote de fiebre hemorrágica altamente letal, el cual se le atribuyó a un Arenavirus cuyo reservorio fue Peromyscus mexicanus. Para determinar hoy en día la posible existencia de Arenavirus en la misma
Lorenzo, Consuelo, Carrillo Reyes, Arturo, Rioja, Tamara M., Álvarez Castañeda, Sergio Ticul   +3 more
core   +1 more source

CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor

Viruses, 2021
Lassa virus (LASV)—a member of the family Arenaviridae—causes Lassa fever in humans and is endemic in West Africa. Currently, no approved drugs are available.
Toru Takenaga, Zihan Zhang, Yukiko Muramoto, Sarah Katharina Fehling, Ai Hirabayashi, Yuki Takamatsu, Junichi Kajikawa, Sho Miyamoto, Masahiro Nakano, Shuzo Urata, Allison Groseth, Thomas Strecker, Takeshi Noda   +12 more
doaj   +1 more source

A high-throughput fluorescence polarization assay to discover inhibitors of arenavirus and coronavirus exoribonucleases

bioRxiv, 2021
Viral exoribonucleases are uncommon in the world of RNA viruses. To date, this activity has been identified only in the Arenaviridae and the Coronaviridae families.
Sergio Hernández, M. Feracci, Carolina Trajano De Jesus, Priscila El-Kazzi, R. Kaci, L. Garlatti, E. Decroly, B. Canard, F. Ferron, K. Alvarez   +9 more
semanticscholar   +1 more source

Envelope exchange for the generation of live-attenuated arenavirus vaccines. [PDF]

PLoS Pathogens, 2006
Arenaviruses such as Lassa fever virus cause significant mortality in endemic areas and represent potential bioterrorist weapons. The occurrence of arenaviral hemorrhagic fevers is largely confined to Third World countries with a limited medical ...
Andreas Bergthaler, Nicolas U Gerber, Doron Merkler, Edit Horvath, Juan Carlos de la Torre, Daniel D Pinschewer   +5 more
doaj   +2 more sources

Seroprevalence of arenavirus and hantavirus in indigenous populations from the Caribbean, Colombia

Revista da Sociedade Brasileira de Medicina Tropical, 2019
INTRODUCTION: In Colombia, there is insufficient epidemiological surveillance of zoonotic hemorrhagic viruses. METHODS: We performed a sero-epidemiological study in indigenous populations of Wayuü, Kankuamos, and Tuchin communities using Maciel ...
Amada Bolaños, Carolina Montoya-Ruiz, Juan Camilo Perez-Peréz, Juan David Rodas, Salim Mattar   +4 more
doaj   +1 more source

Serological Assays Based on Recombinant Viral Proteins for the Diagnosis of Arenavirus Hemorrhagic Fevers

Viruses, 2012
The family Arenaviridae, genus Arenavirus, consists of two phylogenetically independent groups: Old World (OW) and New World (NW) complexes. The Lassa and Lujo viruses in the OW complex and the Guanarito, Junin, Machupo, Sabia, and Chapare viruses in the
Masayuki Saijo, Shigeru Morikawa, Tomoki Yoshikawa, Hideki Tani, Shuetsu Fukushi   +4 more
doaj   +1 more source

The Janus Kinase Inhibitor Ruxolitinib Prevents Terminal Shock in a Mouse Model of Arenavirus Hemorrhagic Fever

Microorganisms, 2021
Arenaviruses such as Lassa virus cause arenavirus hemorrhagic fever (AVHF), but protective vaccines and effective antiviral therapy remain unmet medical needs.
M. Şahin, M. Remy, D. Merkler, D. Pinschewer   +3 more
semanticscholar   +1 more source

The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion.

PLoS Pathogens, 2021
Arenavirus entry into host cells occurs through a low pH-dependent fusion with late endosomes that is mediated by the viral glycoprotein complex (GPC). The mechanisms of GPC-mediated membrane fusion and of virus targeting to late endosomes are not well ...
Ruben M Markosyan, Mariana Marin, You Zhang, Fredric S Cohen, Gregory B Melikyan   +4 more
doaj   +1 more source

Density-dependence and persistence of Morogoro arenavirus transmission in a fluctuating population of its reservoir host.

Journal of Animal Ecology, 2020
1.A key aim in wildlife disease ecology is to understand how host and parasite characteristics influence parasite transmission and persistence. Variation in host population density can have strong impacts on transmission and outbreaks, and theory ...
J. Mariën, B. Borremans, Christophe Verhaeren, Lucinda Kirkpatrick, S. Gryseels, Joëlle Goüy de Bellocq, S. Günther, C. Sabuni, A. Massawe, J. Reijniers, H. Leirs   +10 more
semanticscholar   +1 more source

Diagnóstico virológico y molecular de virus transmitidos por roedores. Hantavirus y arenavirus [PDF]

Revista Mvz Cordoba, 2010
Los hantavirus (familia Bunyaviridae) y arenavirus (familia Arenaviridae) son virus de roedores; cada uno de ellos parece estar estrictamente asociado con una especie de roedor en la que causa una infección persistente y asintomática.
Silvana Levis
doaj