Results 21 to 30 of about 7,989 (190)
Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties [PDF]
Cell Reports MedicineSummary: The non-cytopathic arenavirus lymphocytic choriomeningitis virus (LCMV) induces strong anti-tumor responses. To generate an optimized arenavirus for tumor therapy, we passage LCMV in human or murine tumor cells.
Philipp A. Lang +21 more
doaj +2 more sources
Comparative studies on Mopeia viruses and other Arenaviridae, particularly Lassa virus [PDF]
, 1983 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Serologically related arenaviruses have been isolated from West Africa, Mozambique, Zimbabwe and the Central African Republic.
Lloyd, Graham
core +7 more sources
Generation of Reporter-Expressing New World Arenaviruses: A Systematic Comparison
Viruses, 2022 Replication-competent reporter-expressing viruses are crucial tools in molecular virology with applications that range from antiviral screening to live-cell imaging of protein spatiotemporal dynamics.
Lucie Fénéant +3 more
doaj +1 more source
Viruses, 2022 Arenaviruses include important zoonotic pathogens that cause hemorrhagic fever (e.g., Junín virus; JUNV) as well as other viruses that are closely related but apathogenic (e.g., Tacaribe virus; TCRV).
Julia Holzerland +2 more
doaj +1 more source
Highly Diverse Arenaviruses in Neotropical Bats, Brazil
Emerging Infectious Diseases, 2022 We detected arenavirus RNA in 1.6% of 1,047 bats in Brazil that were sampled during 2007–2011. We identified Tacaribe virus in 2 Artibeus sp. bats and a new arenavirus species in Carollia perspicillata bats that we named Tietê mammarenavirus.
Luiz Gustavo Bentim Góes +14 more
doaj +1 more source
Visualizing lymphocytic choriomeningitis virus infection in cells and living mice
iScience, 2022 Summary: Mammarenavirus are a large family of enveloped negative-strand RNA viruses that include several agents responsible for severe hemorrhagic fevers.
Yuxi Wen +11 more
doaj +1 more source
Cellular endosomal potassium ion flux regulates arenavirus uncoating during virus entry
bioRxiv, 2023 Lymphocytic choriomeningitis virus (LCMV) is an enveloped and segmented negative-sense RNA virus classified within the Arenaviridae family of the Bunyavirales order.
A. Shaw +10 more
semanticscholar +1 more source
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023 Mammarenaviruses are enveloped RNA viruses that can be associated with rodent-transmitted diseases in humans. Their virions are composed of a nucleocapsid surrounded by a lipid bilayer with glycoprotein (GP) spikes interacting with receptors on target ...
M. Gorzkiewicz +3 more
semanticscholar +1 more source
Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity
bioRxiv, 2023 Many enveloped viruses enter host cells by fusing with acidic endosomes. The fusion activity of multiple viral envelope glycoproteins does not generally affect viral membrane permeability.
You Zhang +4 more
semanticscholar +1 more source
npj Vaccines, 2023 HIV affects more than 38 million people worldwide. Although HIV can be effectively treated by lifelong combination antiretroviral therapy, only a handful of patients have been cured.
Archana V Boopathy +17 more
semanticscholar +1 more source