Results 31 to 40 of about 8,211 (209)

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. [PDF]

open access: yes, 2011
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) emerged as the causal agent of an endemic atypical pneumonia, infecting thousands of people worldwide.
Agudelo, Juliet   +10 more
core   +1 more source

Zoonotic aspects of arenavirus infections [PDF]

open access: yesVeterinary Microbiology, 2010
To date, the International Committee for Taxonomy of Viruses recognizes that the family Arenaviridae contains a unique genus Arenavirus that includes 22 viral species. There are nine additional arenaviruses that either have been discovered recently, or which taxonomic status remains pending.
Charrel, R.N., de Lamballerie, X.
openaire   +3 more sources

Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage [PDF]

open access: yes, 2010
Background Several arenaviruses cause severe hemorrhagic fever and aseptic meningitis in humans for which no licensed vaccines are available. A major obstacle for vaccine development is pathogen heterogeneity within the Arenaviridae family.
Maya F Kotturi   +12 more
core   +2 more sources

Envelope exchange for the generation of live-attenuated arenavirus vaccines. [PDF]

open access: yesPLoS Pathogens, 2006
Arenaviruses such as Lassa fever virus cause significant mortality in endemic areas and represent potential bioterrorist weapons. The occurrence of arenaviral hemorrhagic fevers is largely confined to Third World countries with a limited medical ...
Andreas Bergthaler   +5 more
doaj   +2 more sources

Serological Assays Based on Recombinant Viral Proteins for the Diagnosis of Arenavirus Hemorrhagic Fevers

open access: yesViruses, 2012
The family Arenaviridae, genus Arenavirus, consists of two phylogenetically independent groups: Old World (OW) and New World (NW) complexes. The Lassa and Lujo viruses in the OW complex and the Guanarito, Junin, Machupo, Sabia, and Chapare viruses in the
Masayuki Saijo   +4 more
doaj   +1 more source

Inhibition of Arenavirus Entry and Replication by the Cell-Intrinsic Restriction Factor ZMPSTE24 Is Enhanced by IFITM Antiviral Activity

open access: yesFrontiers in Microbiology, 2022
In the absence of effective vaccines and treatments, annual outbreaks of severe human haemorrhagic fever caused by arenaviruses, such as Lassa virus, continue to pose a significant human health threat.
Robert J. Stott-Marshall   +1 more
doaj   +1 more source

A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 Protease. [PDF]

open access: yes, 2016
UNLABELLED: Arenaviruses are emerging viruses including several causative agents of severe hemorrhagic fevers in humans. The advent of next-generation sequencing technology has greatly accelerated the discovery of novel arenavirus species.
Bergeron, E.   +7 more
core   +1 more source

Seroprevalence of arenavirus and hantavirus in indigenous populations from the Caribbean, Colombia

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2019
INTRODUCTION: In Colombia, there is insufficient epidemiological surveillance of zoonotic hemorrhagic viruses. METHODS: We performed a sero-epidemiological study in indigenous populations of Wayuü, Kankuamos, and Tuchin communities using Maciel ...
Amada Bolaños   +4 more
doaj   +1 more source

CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor

open access: yesViruses, 2021
Lassa virus (LASV)—a member of the family Arenaviridae—causes Lassa fever in humans and is endemic in West Africa. Currently, no approved drugs are available.
Toru Takenaga   +12 more
doaj   +1 more source

Arenavirus budding resulting from viral-protein-associated cell membrane curvature [PDF]

open access: yes, 2013
Viral replication occurs within cells, with release (and onward infection) primarily achieved through two alternative mechanisms: lysis, in which virions emerge as the infected cell dies and bursts open; or budding, in which virions emerge gradually from
Abelson HT   +18 more
core   +1 more source

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