Results 11 to 20 of about 23,401,483 (196)

Animal Models of Pathogenic New World Arenaviruses

Microorganisms
Since the emergence of Junín virus in 1953, pathogenic New World arenaviruses have remained a public health concern. These viruses, which also include Machupo virus, Guanarito virus, Sabiá virus, and Chapare virus, cause acute viral hemorrhagic fever and
Alexander V. Alvarado, Robert W. Cross, Thomas W. Geisbert, Courtney Woolsey   +3 more
doaj   +4 more sources

Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses

mSphere, 2018
Arenaviruses pose a major public health threat and cause numerous infections in humans each year. Although most viruses belonging to this family do not cause disease in humans, some arenaviruses, such as Lassa virus and Machupo virus, are the etiological
Fatima Amanat, James Duehr, Lisa Oestereich, Kathryn M. Hastie, Erica Ollmann Saphire, Florian Krammer   +5 more
doaj   +5 more sources

Host-species transferrin receptor 1 orthologs are cellular receptors for nonpathogenic new world clade B arenaviruses. [PDF]

PLoS Pathogens, 2009
The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever.
Jonathan Abraham, Jo Ann Kwong, César G Albariño, Jiajie G Lu, Sheli R Radoshitzky, Jorge Salazar-Bravo, Michael Farzan, Christina F Spiropoulou, Hyeryun Choe   +8 more
doaj   +7 more sources

Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses [PDF]

Nature Communications, 2018
The five known New World hemorrhagic fever arenaviruses use the same entry receptor, but their viral glycoproteins are markedly different. Here, the authors isolate monoclonal antibodies from a Junin virus vaccinated person that cross-neutralize Machupo ...
Lars E. Clark, Selma Mahmutovic, Donald D. Raymond, Taleen Dilanyan, Takaaki Koma, John T. Manning, Sundaresh Shankar, Silvana C. Levis, Ana M. Briggiler, Delia A. Enria, Kai W. Wucherpfennig, Slobodan Paessler, Jonathan Abraham   +12 more
doaj   +9 more sources

The Phylogeny of New World (Tacaribe Complex) Arenaviruses [PDF]

Virology, 1996
Several New World (Tacaribe complex) arenaviruses (Arenaviridae) are known to cause severe hemorrhagic disease in humans. Phylogenetic reconstruction of the Tacaribe complex arenaviruses previously has been limited by the relative scarcity of sequence ...
NICHOL, STUART T., BOWEN, MICHAEL D., PETERS, CLARENCE J.   +2 more
core   +3 more sources

Co-circulation of Clade C New World Arenaviruses: New geographic distribution and host species [PDF]

Infection, Genetics and Evolution, 2015
Clade C, of the New World Arenaviruses, is composed of only the Latino and Oliveros viruses and, besides the geographic range of their rodent reservoirs, the distribution of these viruses has been restricted to Bolivia and Argentina.
Levis, Silvana, D'Andrea, Paulo Sergio, D’Andrea, Paulo Sergio, Oliveira, Renata Carvalho de, Bonvicino, Cibele Rodrigues, de Lemos, Elba Regina Sampaio, Fernandes, Jorlan, de Carvalho Serra, Fabiana, Cunha, Rivaldo Venâncio, Guterres, Alexandro, Lemos, Elba Regina Sampaio de, Serra, Fabiana de Carvalho, de Oliveira, Renata Carvalho   +12 more
core   +3 more sources

Differential Immune Responses to New World and Old World Mammalian Arenaviruses [PDF]

International Journal of Molecular Sciences, 2017
Some New World (NW) and Old World (OW) mammalian arenaviruses are emerging, zoonotic viruses that can cause lethal hemorrhagic fever (HF) infections in humans.
Hinh Ly
core   +3 more sources

Different mechanisms of cell entry by human-pathogenic Old World and New World arenaviruses. [PDF]

Journal of Virology, 2008
The Old World arenavirus Lassa virus (LASV) is the causative agent of severe viral hemorrhagic fever (VHF) in humans and is the most prevalent human pathogen among arenaviruses.
de la Torre, J.C., Rojek, J.M., Kunz, S., Nguyen, N.T., Sanchez, A.B.   +4 more
core   +4 more sources

Comparison of the Innate Immune Responses to Pathogenic and Nonpathogenic Clade B New World Arenaviruses [PDF]

Journal of Virology, 2019
The New World (NW) arenaviruses are a diverse group of zoonotic viruses, including several causative agents of severe hemorrhagic fevers in humans. All known human-pathogenic NW arenaviruses belong to Glade B, where they group into sublineages with ...
Fedeli, Chiara, Moreno, H., Kunz, Stefan, Gerold, G., Moreno, Hector, Moeller, Rebecca, Kunz, S., Möller, R., Fedeli, C., Gerold, Gisa,   +9 more
core   +4 more sources

Differential Immune Responses to Hemorrhagic Fever-Causing Arenaviruses

Vaccines, 2019
The family Arenaviridae contains several pathogens of major clinical importance. The Old World (OW) arenavirus Lassa virus is endemic in West Africa and is estimated to cause up to 300,000 infections each year.
Emily Mantlo, Slobodan Paessler, Cheng Huang   +2 more
doaj   +2 more sources