Results 21 to 30 of about 23,401,483 (196)
PLoS Neglected Tropical Diseases, 2023 Numerous arenaviruses have been identified throughout the Americas and a subset of these viruses cause viral hemorrhagic fever in humans. This study compared the pathology and viral RNA distribution in Hartley guinea pigs challenged with two human ...
Curtis Cline +10 more
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Distinct Biological and Epidemiological Features of Old World and New World Arenaviruses
Karbala Journal of MedicineDear Sir, The Arenaviridae family comprises a diverse group of enveloped, bisegmented, negative-sense RNA viruses that establish persistent infections in rodent hosts and occasionally transmit zoonotically to humans [1-2].
Hussin Rothan
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Serpin-based SKI-1/S1P inhibitors against Old and New World arenaviruses [PDF]
, 2011 The importance of arenavirus glycoprotein processing has only been understood within the past decade, with the majority of work focused on the Old World arenaviruses.
Chan, Mable W. S.
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Comparative studies on Mopeia viruses and other Arenaviridae, particularly Lassa virus [PDF]
, 1983 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Serologically related arenaviruses have been isolated from West Africa, Mozambique, Zimbabwe and the Central African Republic.
Lloyd, Graham
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mBio, 2022 Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng +9 more
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Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa. [PDF]
PLoS Pathogens, 2009 Lujo virus (LUJV), a new member of the family Arenaviridae and the first hemorrhagic fever-associated arenavirus from the Old World discovered in three decades, was isolated in South Africa during an outbreak of human disease characterized by nosocomial ...
Thomas Briese +11 more
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Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses [PDF]
Proceedings of the National Academy of Sciences, 2008 Transferrin receptor 1 (TfR1) is a cellular receptor for the New World hemorrhagic fever arenaviruses Machupo (MACV), Junín (JUNV), and Guanarito (GTOV). Each of these viruses is specifically adapted to a distinct rodent host species, but all cause human disease. Here we compare the ability of these viruses to use various mammalian
Sheli R, Radoshitzky +11 more
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Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses [PDF]
Nature Structural & Molecular Biology, 2010 New World hemorrhagic fever arenaviruses are rodent-borne agents that cause severe human disease. The GP1 subunit of the surface glycoprotein mediates cell attachment through transferrin receptor 1 (TfR1). We report the structure of Machupo virus (MACV) GP1 bound with human TfR1.
Abraham, Jonathan +4 more
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Machupo virus glycoprotein determinants for human transferrin receptor 1 binding and cell entry. [PDF]
PLoS ONE, 2011 Machupo virus (MACV) is a highly pathogenic New World arenavirus that causes hemorrhagic fever in humans. MACV, as well as other pathogenic New World arenaviruses, enter cells after their GP1 attachment glycoprotein binds to their cellular receptor ...
Sheli R Radoshitzky +8 more
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Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses [PDF]
Nature, 2007 At least five arenaviruses cause viral haemorrhagic fevers in humans. Lassa virus, an Old World arenavirus, uses the cellular receptor alpha-dystroglycan to infect cells. Machupo, Guanarito, Junin and Sabia viruses are New World haemorrhagic fever viruses that do not use alpha-dystroglycan.
Radoshitzky, Sheli R. +11 more
openaire +2 more sources