Results 71 to 80 of about 6,856 (207)

High Diversity of RNA Viruses in Rodents, Ethiopia

Emerging Infectious Diseases, 2012
We investigated synanthropic small mammals in the Ethiopian Highlands as potential reservoirs for human pathogens and found that 2 rodent species, the Ethiopian white-footed mouse and Awash multimammate mouse, are carriers of novel Mobala virus strains ...
Yonas Meheretu, Dagmar Čížková, Jana Těšíková, Kiros Welegerima, Zewdneh Tomas, Dawit Kidane, Kokob Girmay, Jonas Schmidt-Chanasit, Josef Bryja, Stephan Günther, Anna Bryjová, Herwig Leirs, Joëlle Goüy de Bellocq   +12 more
doaj   +1 more source

Evaluating the Potential Adverse Effects of Favipiravir on Biochemical, Histopathological, and Spermatological Parameters in Male Rats' Testicular Tissue

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
ABSTRACT Favipiravir is a selective RNA polymerase inhibitor and a broad‐spectrum antiviral drug. Favipiravir reduces cell proliferation by inhibiting RNA transcription, particularly in rapidly proliferating cells such as spermatogonia. The aim of this study was to investigate the effects and mechanism of action of favipiravir (T‐705) on sperm quality ...
Ali Doğan Ömür, Gamze Uçak, Adem Kara, Elif Erbaş, Serkan Ali Akarsu, Seçkin Özkanlar, Nevra Aydemir Celep   +6 more
wiley   +1 more source

Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]

, 2015
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien, Cognasse, Fabrice, Garraud, Olivier, Gomez, Ricardo Martin, Hamzeh Cognasse, Hind, Pozzetto, Bruno, Schattner, Mirta Ana   +6 more
core   +2 more sources

Preparedness of Emergency Room Nurses for Bioterrorism Based on the Health Belief Model: A Multicenter Qualitative Study

International Nursing Review, Volume 72, Issue 2, June 2025.
ABSTRACT Aim To explore emergency room nurses’ perceptions of preparedness for bioterrorism. Introduction In the context of evolving global security threats, including wars, terrorism, and emerging infectious diseases, it is critical to evaluate the bioterrorism response competencies of emergency room nurses and identify strategies to enhance their ...
Mi‐Kyeong Jeon, Yujeong Kim
wiley   +1 more source

Arenavirus Budding

Advances in Virology, 2011
Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions. On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus-host interactions
Shuzo Urata, Juan Carlos de la Torre
doaj   +1 more source

Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer

Journal of Internal Medicine, Volume 297, Issue 6, Page 608-629, June 2025.
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic, Ourania N. Kostopoulou, Linda Marklund, Tina Dalianis   +3 more
wiley   +1 more source

Arenavirus Diversity and Phylogeography of Mastomys natalensis Rodents, Nigeria

Emerging Infectious Diseases, 2016
Mastomys natalensis rodents are natural hosts for Lassa virus (LASV). Detection of LASV in 2 mitochondrial phylogroups of the rodent near the Niger and Benue Rivers in Nigeria underlines the potential for LASV emergence in fresh phylogroups of this ...
Ayodeji Olayemi, Adeoba Obadare, Akinlabi Oyeyiola, Joseph Igbokwe, Ayobami Fasogbon, Felix Igbahenah, Daniel Ortsega, Danny Asogun, Prince Umeh, Innocent Vakkai, Chukwuyem Abejegah, Meike Pahlman, Beate Becker-Ziaja, Stephan Günther, Elisabeth Fichet-Calvet   +14 more
doaj   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet, Barnard, Dale, Carrion, Ricardo, Lu, Kai, McKerrow, James H, Nunneley, Jerritt W, Pöhlmann, Stefan, Renslo, Adam R, Simmons, Graham, Vedantham, Punitha, Zhou, Yanchen   +10 more
core   +1 more source

Pathogenic Mechanisms Involved in the Hematological Alterations of Arenavirus-induced Hemorrhagic Fevers

Viruses, 2013
Viral hemorrhagic fevers (VHFs) caused by arenaviruses are acute diseases characterized by fever, headache, general malaise, impaired cellular immunity, eventual neurologic involvement, and hemostatic alterations that may ultimately lead to shock and ...
Roberto G. Pozner, Ricardo M. Gómez, Mirta Schattner, Leonardo Rivadeneyra   +3 more
doaj   +1 more source