Results 61 to 70 of about 65,972 (187)
Respiratory Research, 2011 Background Arginase overexpression contributes to airways hyperresponsiveness (AHR) in asthma. Arginase expression is further augmented in cigarette smoking asthmatics, suggesting that it may be upregulated by environmental pollution.
Amatullah Hajera +6 more
doaj +1 more source
Detrimental Effects of Chronic L-Arginine Rich Food on Aging Kidney
Frontiers in Pharmacology, 2021 The impaired L-arginine/nitric oxide pathway is a well-recognized mechanism for cardiovascular and renal diseases with aging. Therefore, supplementation of L-arginine is widely proposed to boost health or as adjunct therapy for the patients.
Ji Huang +8 more
doaj +1 more source
Hyperargininemia with Arginase Deficiency [PDF]
Pediatric Research, 1979 Summary: A female and a male sibling aged 15 and 8 yr developed almost normally for 3 yr, then gradually deteriorated intellectually and physically. Both patients showed marked hyperargininuria (up to 370 times normal), prominent lysinuria, cystinuria, and ornithinuria, and a milder generalized amino aciduria.
S D, Cederbaum +5 more
openaire +2 more sources
Neuroblastoma arginase activity creates an immunosuppressive microenvironment that impairs autologous and engineered immunity [PDF]
, 2015 Neuroblastoma is the most common extra cranial solid tumour of childhood, and survival remains poor for patients with advanced disease. Novel immune therapies are currently in development, but clinical outcomes have not matched preclinical results. Here,
Borsheim +25 more
core +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Arginase II activity contributes to reciprocal regulation of endothelial nitric oxide synthase (eNOS). We tested the hypotheses that arginase II activity participates in the regulation of Ca2+/Ca2+/calmodulin‐dependent kinase II/eNOS ...
Bon‐Hyeock Koo +10 more
doaj +1 more source
Helicobacter pylori arginase mutant colonizes arginase II knockout mice
World Journal of Gastroenterology, 2011 To investigate the role of host and bacterial arginases in the colonization of mice by Helicobacter pylori (H. pylori).H. pylori produces a very powerful urease that hydrolyzes urea to carbon dioxide and ammonium, which neutralizes acid. Urease is absolutely essential to H.
Songhee H, Kim +4 more
openaire +2 more sources
Granulocytic myeloid-derived suppressor cells increased in early phases of primary HIV infection depending on TRAIL plasma level [PDF]
, 2017 Background It has been demonstrated that Myeloid Derived Suppressor Cells (MDSC) are expanded in HIV-1 infected individuals and correlated with disease progression.
Abbate, Isabella +13 more
core +1 more source
The conversion of citrulline to arginine in kidney [PDF]
, 1941 Glycocyamine is formed in the kidney by the transfer of the amidine group of arginine to the nitrogen atom of glycine. In the study of this reaction it was observed that glycocyamine was also formed from citrulline and glycine.
Borsook, Henry, Dubnoff, Jacob W.
core
Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]
, 2013 This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Adrian J. Thrasher +14 more
core +2 more sources
Frontiers in Pharmacology, 2018 It is well known that arginase II leads to decreased synthesis of nitric oxide (NO) by competing with endothelial nitric oxide synthase (eNOS) for their same substrate L-arginine.
Qi Wang +10 more
doaj +1 more source