Results 41 to 50 of about 115,664,573 (187)

PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway

Molecular Oncology, 2022
Phosphoglycerate mutase 1 (PGAM1) is a crucial glycolytic enzyme, and its expression status has been confirmed to be associated with tumor progression and metastasis. However, the precise role and other biological functions of PGAM1 remain unclear. Here,
Min Liu, Runmei Li, Min Wang, Ting Liu, Qiuru Zhou, Dong Zhang, Jian Wang, Meng Shen, Xiubao Ren, Qian Sun   +9 more
doaj   +1 more source

The central metabolism of M. alcaliphilum 20Z.

, 2023
1 –hexulose 6-phosphate synthase, 2 –phosphohexuloisomerase 3 –PPi-dependent 6-phosphofructokinase, 4 –glyceraldehyde-3-phosphate dehydrogenase, 5 –pyruvate dehydrogenase complex, 6 –citrate synthase, 7 –aconitase, 8 –isocitrate dehydrogenase, 9 – α ...
Valentina N. Khmelenina (7878662), Ildar I. Mustakhimov (7878653), Alexander S. Reshetnikov (17290975), Maxim V. Molchanov (17290978), Oleg I. Melnikov (17290972), Andrey V. Machulin (7300226), Olga N. Rozova (7878650)   +6 more
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Arginine Metabolism and Its Potential in Treatment of Colorectal Cancer

Frontiers in Cell and Developmental Biology, 2021
Colorectal cancer is the leading cause of death from cancer globally. The current treatment protocol still heavily relies on early detection and surgery.
Tao Du, Junyi Han
doaj   +1 more source

ASS1 Overexpression: A Hallmark of Sonic Hedgehog Hepatocellular Adenomas; Recommendations for Clinical Practice

Hepatology Communications, 2020
Until recently, 10% of hepatocellular adenomas (HCAs) remained unclassified (UHCA). Among the UHCAs, the sonic hedgehog HCA (shHCA) was defined by focal deletions that fuse the promoter of Inhibin beta E chain with GLI1.
Margaux Sala, Delphine Gonzales, Thierry Leste‐Lasserre, Nathalie Dugot‐Senant, Valérie Paradis, Sylvaine Di Tommaso, Jean‐William Dupuy, Vincent Pitard, Cyril Dourthe, Amedeo Sciarra, Christine Sempoux, Linda D. Ferrell, Andrew D. Clouston, Gregory Miller, Mathew M. Yeh, Swan Thung, Annette S.H. Gouw, Alberto Quaglia, Jing Han, Ji Huan, Cathy Fan, James Crawford, Yasuni Nakanuma, Kenichi Harada, Brigitte leBail, Claire Castain, Nora Frulio, Hervé Trillaud, Laurent Possenti, Jean‐Frédéric Blanc, Laurence Chiche, Christophe Laurent, Charles Balabaud, Paulette Bioulac‐Sage, Anne Aurélie Raymond, Frédéric Saltel   +35 more
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Structure of human argininosuccinate synthetase

, 2008
Argininosuccinate synthetase catalyzes the transformation of citrulline and aspartate into argininosuccinate and pyrophos­phate using the hydrolysis of ATP to AMP and pyrophos­phate.
Karlberg, T., van den Berg, S., Flores, A., Hammarstrom, M., Collins, R., Uppenberg, J., Holmberg Schiavone, L., Hogbom, M., Karlberg, T,, Flores, A, Schiavone, LH, Collins, R,, Hammarstrom, M, Hogbom, M, van, den Berg S,, Uppenberg, J   +15 more
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Protective effects and mechanisms of N-acetylcysteine on indomethacin-induced intestinal injury in a porcine model

Ecotoxicology and Environmental Safety, 2023
This study aimed to investigate the effect of N-acetylcysteine (NAC) on indomethacin (IDMT)-induced intestinal injury in a piglet model and explore the underlying molecular mechanisms.
Qian Zhang, Wenkai Liu, Qian Li, Yitong Zeng, Mengjun Wu, Tao Wu, Shuangshuang Guo, Lei Wang, Di Zhao, Dan Yi, Yongqing Hou   +10 more
doaj   +1 more source

Prenatal diagnosis of citrullinemia type 1; seven families with c.1168G>A mutation of Argininosuccinate synthetase 1 gene in Southwest Iran: A case series [PDF]

, 2022
Background: Citrullinemia type 1 is an autosomal recessive disease resulting in ammonia accumulation in the blood, and if uncontrolled may progress to coma or death in the early months after birth.
Zeinali, Sirous, Hassanlou, Maryam, Abiri, Maryam, Maryam Hassanlou, Sirous Zeinali, Maryam Abiri   +5 more
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Effects of Dietary Sodium Butyrate on Growth Performance, Digestive Ability, Blood Biochemistry, and Ammonia Tolerance of Largemouth Bass (Micropterus salmoides)

Fishes
The aim of this study was to investigate the effects of sodium butyrate (SB) on growth performance, digestive ability, blood health, and ammonia tolerance of largemouth bass.
Xuan Chen, Wu Chen, Yanjie Tang, Muzi Zhang, Ming Li   +4 more
doaj   +1 more source

l-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo

Journal of Pharmacological Sciences, 2015
l-Citrulline is an effective precursor of l-arginine produced by the l-citrulline/l-arginine cycle, and it exerts beneficial effects on the cardiovascular system by supporting enhanced nitric oxide (NO) production.
Asami Mori, Masahiko Morita, Koji Morishita, Kenji Sakamoto, Tsutomu Nakahara, Kunio Ishii   +5 more
doaj   +1 more source

An assay for argininosuccinate synthetase in Neurospora [PDF]

, 1965
An assay for argininosuccinate synthetase in ...
Fairley, J. L., J. L. Fairley, Wampler, D. E., D. E. Wampler   +3 more
core   +1 more source