Results 61 to 70 of about 115,664,573 (187)

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

A patient with argininosuccinate synthase 1 positive unclassified hepatocellular adenoma causing intratumoral hemorrhage

Kanzo, 2019
We report the first Japanese patient with unclassified hepatocellular adenoma who presented with acute pain in the abdomen due to intratumoral hemorrhage and whose immunohistological study revealed high tumoral expression of argininosuccinate synthase 1 (
Hidetaka Takashima, S. Mizuno, Takahiro Mori, Chihiro Yokomizo, Kyohei Ikeda, K. Ogiso, Hirokazu Uejima, Tadashi Ito, H. Tomioka, Toshiyuki Okamoto, Yuri Nakaseko, Natsuko Hayashi, T. Katoh, Takeshi Masaki, S. Shimizu, M. Moriguchi, Y. Nakanuma   +16 more
semanticscholar   +1 more source

Genetic Manipulation of Leishmania donovani to Explore the Involvement of Argininosuccinate Synthase in Oxidative Stress Management.

, 2016
Reactive oxygen and nitrogen species (ROS and RNS) produced by the phagocytic cells are the most common arsenals used to kill the intracellular pathogens.
Abul Hasan Sardar, Kumar Abhishek (848214), Armando Jardim, Abhishek Mandal, Ruby Singh, Sushmita Das, Kumar Abhishek, Ajay Kumar, Ayan Kumar Ghosh (583767), Ajay Kumar (192967), Sushmita Das (42342), Savita Saini, Abhishek Mandal (848211), Ayan Kumar Ghosh, Ruby Singh (847243), Pradeep Das, Sudha Verma (848213), Pradeep Das (230639), Abul Hasan Sardar (573177), Armando Jardim (125779), Savita Saini (728002), Sudha Verma   +21 more
core   +1 more source

RETRACTED ARTICLE: N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 expression in an m6A-dependent manner

, 2022
The Publisher of the journal Bioengineered, have retracted the following article: Miao YQ, Chen W, Zhou J, Shen Q, Sun Y, Li T, Wang SC. N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 ...
Ying Sun (23237), Jianfeng Zhou (53330), Sheng-Chan Wang (11931783), You-Qing Miao (11931780), Tao Li (86810), Wei Chen (23863), Qiyang Shen (4501231)   +6 more
core   +1 more source

Arginine Deprivation in SCLC: Mechanisms and Perspectives for Therapy

Lung Cancer: Targets and Therapy, 2022
Joséphine Carpentier,1 Iuliia Pavlyk,1 Uma Mukherjee,2 Peter E Hall,2 Peter W Szlosarek1,2 1Centre for Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK; 2Department of Medical Oncology ...
Carpentier J, Pavlyk I, Mukherjee U, Hall PE, Szlosarek PW   +4 more
doaj  

L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia

Respiratory Research, 2012
Background Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a consequence. L-arginine can also be synthesized by L-citrulline recycling.
Sopi Ramadan B, Zaidi Syed IA, Mladenov Mitko, Sahiti Hazbije, Istrefi Zahide, Gjorgoski Icko, Lajçi Azem, Jakupaj Muharrem   +7 more
doaj   +1 more source

Protein levels of arginine-related enzymes in the STZ offspring kidney.

, 2013
(A) Representative western blots showing arginase II (Arg II, ∼40 kDa), cationic amino acid transporter-1 (CAT-1, ∼68 kDa), argininosuccinate synthase (ASS, ∼50 kDa), and argininosuccinate lysate (ASL, ∼50 kDa) bands.
Chien-Te Lee (280488), Chien-Ning Hsu (280485), Wei-Chia Lee (280486), You-Lin Tain (280484), Wen-Chin Lee (150376), Li-Tung Huang (280487), Ching-Yuang Lin (280489)   +6 more
core   +1 more source

Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis. [PDF]

, 2012
BACKGROUND: Gene expression analysis in Leishmania donovani (Ld) identified an orthologue of the urea cycle enzyme, argininosuccinate synthase (LdASS), that was more abundantly expressed in amastigotes than in promastigotes.
Rona Strasser, Armando Jardim, Shen Luo, Hira L Nakhasi, Ines Lakhal-Naouar (125773), Robert C. Duncan (125794), Robert C Duncan, Shen Luo (125786), Rona Strasser (125782), Hira L. Nakhasi (125792), Yukiko Kozakai (125789), Yukiko Kozakai, Ines Lakhal-Naouar, Armando Jardim (125779), Strasser Rona, Jardim Armando, Kozakai Yukiko, Lakhal-Naouar Ines, Nakhasi Hira L., Duncan Robert C., Luo Shen   +20 more
core   +1 more source

Effects of dietary D-mannose supplementation on growth performance, intestinal digestive capacity, gut microbiota, and ammonia tolerance of largemouth bass Micropterus salmoides

Aquaculture Reports
To investigate the effects of D-mannose on the growth performance, intestinal digestion capacity, intestinal microbiota composition, and ammonia tolerance of largemouth bass, experiments were conducted using largemouth bass fry with an average body ...
Changyi Sun, Muzi Zhang, Dexiang Feng, Shidong Wang, Ming Li   +4 more
doaj   +1 more source

Suggested guidelines for the diagnosis and management of urea cycle disorders

Orphanet Journal of Rare Diseases, 2012
Urea cycle disorders (UCDs) are inborn errors of ammonia detoxification/arginine synthesis due to defects affecting the catalysts of the Krebs-Henseleit cycle (five core enzymes, one activating enzyme and one mitochondrial ornithine/citrulline antiporter)
Häberle Johannes, Boddaert Nathalie, Burlina Alberto, Chakrapani Anupam, Dixon Marjorie, Huemer Martina, Karall Daniela, Martinelli Diego, Crespo Pablo, Santer René, Servais Aude, Valayannopoulos Vassili, Lindner Martin, Rubio Vicente, Dionisi-Vici Carlo   +14 more
doaj   +1 more source