Results 71 to 80 of about 110,455,116 (191)

Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation

The Journal of Physiology, EarlyView.
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min, Órlaith C. Henry, Luke A. J. O'Neill   +2 more
wiley   +1 more source

Primers used for qPCR.

, 2014
CPS1, carbamoyl phosphate synthetase 1; OTC, ornithine carbamoyltransferase; ASS1, argininosuccinate synthetase; ASL, argininosuccinate lyase; ARG1, arginase; NAGS, N-acetylglutamate synthase; GLUL, glutamate–ammonia ligase; GLUD1, glutamate ...
Giora van Straten (580550), Frank C. P. Holstege (117137), Robert P. Favier (144780), Marian J. A. Groot Koerkamp (117136), Frank G. van Steenbeek (194928), Hille Fieten (144796), Ingrid H. van Gils (580551), Guy C. M. Grinwis (165277), Bart Spee (66184), Jan Rothuizen (66188), Anne Kummeling (381713)   +10 more
core   +1 more source

Effects of Dietary Sodium Butyrate on Growth Performance, Digestive Ability, Blood Biochemistry, and Ammonia Tolerance of Largemouth Bass (Micropterus salmoides)

Fishes
The aim of this study was to investigate the effects of sodium butyrate (SB) on growth performance, digestive ability, blood health, and ammonia tolerance of largemouth bass.
Xuan Chen, Wu Chen, Yanjie Tang, Muzi Zhang, Ming Li   +4 more
doaj   +1 more source

Plant NAOGAT (ArgJ) Structure Reveals Mechanism of Ornithine Biosynthesis, Preference for Acetylornithine and Susceptibility to Mangotoxin

Plant, Cell &Environment, Volume 49, Issue 12, Page 10283-10300, December 2026.
ABSTRACT Arginine metabolism in plants is targeted by phytopathogens such as Pseudomonas syringae strains, which produce toxins that affect enzymes of plant arginine metabolism, causing devastating infections in crops. In this work, the structural and functional properties of plant N‐acetylornithine glutamate acetyltransferase (NAOGAT), the key ...
Maciej Nielipinski, Agnieszka J. Pietrzyk‐Brzezinska, Aleksandra Twarda‐Clapa, Bartosz Sekula   +3 more
wiley   +1 more source

Supplementary Figure 2 from Prognostic and Therapeutic Impact of Argininosuccinate Synthetase 1 Control in Bladder Cancer as Monitored Longitudinally by PET Imaging

, 2023
<p>PDF file - 802K, Metabolomics of ADI-PEG20 in a corroborative cell line panel (mesothelioma).</p>
Peter W. Szlosarek, Chien-Feng Li, Norbert Avril, Jane Sosabowski, Julie Foster, Stephen Mather, Nicholas R. Lemoine, Tim Crook, Yong-Jie Lu, Robert C. Jackson, John S. Bomalaski, Bor-Wen Wu, Claude Chelala, Louise J. Jones, Luis Beltran, Christian Frezza, David Neal, Anne Y. Warren, Hayley C. Whitaker, Rebecca Roylance, Ian Tomlinson, Malgorzata Chmielewska-Kassassir, Laura Lattanzio, Cristiana Lo Nigro, Nelofer Syed, Ming Yuan, Rosalind Cutts, Essam Ghazaly, Barbara Delage, Julius Leyton, Chantelle Hudson, Phuong Luong, Michael D. Allen   +32 more
openaire   +1 more source

Overview on ornithine synthesis and degradation.

, 2019
ADC1/2, arginine decarboxylase 1 and 2; ArgAH, arginine amidohydrolase; ASL, argininosuccinate lyase; ASSY, argininosuccinate synthetase; CARA, carbamoyl phosphate synthetase A; CARB, carbamoyl phosphate synthetase B; NAGS, N-acetyl-L-glutamate synthase;
Miriam Laxa (6236678), Marco Mühlenbruch (6236672), Christoph Peterhänsel (6236675), Christian Blume (6236666), Julia Ost (6236669)   +4 more
core   +1 more source

Supplementary Figure 4 from Prognostic and Therapeutic Impact of Argininosuccinate Synthetase 1 Control in Bladder Cancer as Monitored Longitudinally by PET Imaging

, 2023
<p>PDF file - 177K, Kaplan-Meier plot and log-rank test for disease-specific and metastasis-free survival.</p>
Peter W. Szlosarek, Chien-Feng Li, Norbert Avril, Jane Sosabowski, Julie Foster, Stephen Mather, Nicholas R. Lemoine, Tim Crook, Yong-Jie Lu, Robert C. Jackson, John S. Bomalaski, Bor-Wen Wu, Claude Chelala, Louise J. Jones, Luis Beltran, Christian Frezza, David Neal, Anne Y. Warren, Hayley C. Whitaker, Rebecca Roylance, Ian Tomlinson, Malgorzata Chmielewska-Kassassir, Laura Lattanzio, Cristiana Lo Nigro, Nelofer Syed, Ming Yuan, Rosalind Cutts, Essam Ghazaly, Barbara Delage, Julius Leyton, Chantelle Hudson, Phuong Luong, Michael D. Allen   +32 more
openaire   +1 more source

Mutational analysis of residues involved in substrate binding and catalysis of E. coli argininosuccinate synthetase [PDF]

, 2003
E. coli argininosuccinate synthetase (EAS) catalyzes the reversible ATP dependent ligation of citrulline and aspartate to form argininosuccinate, AMP, and inorganic pyrophosphate.
Huynh, My Ngan
core  

Moderate citrullinaemia without hyperammonaemia in a child with mutated and deficient argininosuccinate synthetase.

, 2003
In a patient with microcephaly, feeding problems and restlessness, moderately increased serum and urine citrulline concentrations were observed. Protein and allopurinol loading did not result in additional indications for a urea cycle defect.
Iijima, M., Engelke, U.F.H., Boelen, C., Smeitink, J.A.M., Kobayashi, K., Jong, J.G.N. de, Saheki, T., Abreu, R.A. de, Ruitenbeek, W., Kwast, H.T., Wevers, R.A.   +10 more
core   +1 more source

Electroencephalography and transcranial Doppler ultrasonography in neonatal citrullinemia

Journal of the Formosan Medical Association, 2014
The authors present a case of citrullinemia with a genotype of argininosuccinate synthetase (ASS1), c.380 G>A (p.R127Q)/c.380 G>A (p.R127Q), in two alleles. A 3-day-old female infant presented with status epilepticus and coma.
Pen-Hua Su, Jia-Yuh Chen, Yung-Jung Chen, Dau-Ming Niu, Ju-Hui Hsu, Inn-Chi Lee   +5 more
doaj   +1 more source