Results 121 to 130 of about 42,927 (266)
Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute
Nature Communications, 2016 Argonaute proteins are important in the silencing machinery with some regulatory RNAs. Here, the authors solve the structure of an argonaute protein in complex with both the guide RNA and target DNA and propose a mechanism for their recognition.
Tomohiro Miyoshi +3 more
doaj +1 more source
Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegypti.
PLoS ONE, 2012 RNA silencing, or RNA interference (RNAi) in metazoans mediates development, reduces viral infection and limits transposon mobility. RNA silencing involves 21-30 nucleotide RNAs classified into microRNA (miRNA), exogenous and endogenous small interfering
Scott A Bernhardt +5 more
doaj +1 more source
PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment
MedComm, Volume 6, Issue 8, August 2025.The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang +10 more
wiley +1 more source
ChildrenBackground: Argonautes (AGOs) are a type of protein that degrade specific messenger RNAs, consequently reducing the expression of a specific gene. These proteins consist of small, single-stranded RNA or DNA and may provide a route for detecting and ...
Zon-Min Lee +4 more
doaj +1 more source
Argonaute Protein in the Early Divergent Eukaryote Trypanosoma brucei: Control of Small Interfering RNA Accumulation and Retroposon Transcript Abundance [PDF]
, 2003 Huafang Shi +3 more
openalex +1 more source
RNA Epigenetics in Cancer: Current Knowledge and Therapeutic Implications
MedComm, Volume 6, Issue 8, August 2025.RNA epigenetics regulates cancer through RNA modifications, splicing, transport, and translation. Key components include m⁶A writers, splicing factors, RBPs, and nuclear export machinery. Aberrant RNA metabolism drives tumor progression and immune evasion.
Shanhe Huang +4 more
wiley +1 more source
ACADEMIA. The magazine of the Polish Academy of SciencesMyths link us all together, across countries and generations. That is why classical mythology is being incorporated into an educational curriculum designed to better equip young people to navigate the challenges of today’s world.
openaire +2 more sources
The Arabidopsis Heterochronic Gene ZIPPY Is an ARGONAUTE Family Member [PDF]
, 2003 Christine Hunter +2 more
openalex +1 more source
Insecticide resistance management scenarios differ for RNA‐based sprays and traits
Insect Molecular Biology, Volume 34, Issue 4, Page 518-526, August 2025.dsRNA insecticides are developed as transgenic traits or sprays. IRM for dsRNA traits is based on stacked modes of action and a refuge. IRM for dsRNA sprays is based on rotating dsRNA with different modes of action insecticides. Abstract RNA‐based bioinsecticides that comprise a dsRNA active ingredient and function by RNA interference (RNAi) are being ...
Kenneth Narva +8 more
wiley +1 more source