Results 111 to 120 of about 30,324 (235)
Argonauts Of The Western Pacific
Setelah pembahasan yang agak panjang tentang ilmu sihir, sekarang kita dapat kembali lagi ke deskripsi tentang Kula. Sejauh ini, kita hanya membahas satu kejadian di dalamnya, ekspedisi luar negeri antara Sinaketa dan Dobu, dan kunjungan balasan. Namun, dalam membahas satu tahap khas ini, kita telah memperoleh gambaran tentang seluruh Kula, dan secara ...
openaire +2 more sources
➢Extracellular vesicles (EVs) mediate the coupling of angiogenesis and neurogenesis. ➢Ischemic cerebral endothelial cell (CEC) derived EVs enhance neurogenesis. ➢EVs derived from either non‐ischemic or ischemic neural stem cells (NSCs) promote in vitro angiogenesis. ➢EV‐transmitted miRNAs regulate stroke‐induced neurogenesis and angiogenesis.
Xianshuang Liu +8 more
wiley +1 more source
Nucleic Acid Therapeutics in Rare Disease: From Precision Medicine to Programmable Platforms
ABSTRACT Nucleic acid therapeutics (NATs), including antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), messenger RNA (mRNA) therapeutics and programmable editing technologies, are reshaping the therapeutic landscape for inherited metabolic and genetic disease.
Tomasz Z. Tomkiewicz +3 more
wiley +1 more source
Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu +8 more
wiley +1 more source
Gene turnover in the common ancestor of all C4 grasses
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira +6 more
wiley +1 more source
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden +3 more
wiley +1 more source
RNA interference (RNAi) is a conserved pathway that utilizes Argonaute proteins and their associated small RNAs to exert gene regulatory function on complementary transcripts.
Shihui Chen, Carolyn Marie Phillips
doaj +1 more source
Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute
Argonaute proteins are important in the silencing machinery with some regulatory RNAs. Here, the authors solve the structure of an argonaute protein in complex with both the guide RNA and target DNA and propose a mechanism for their recognition.
Tomohiro Miyoshi +3 more
doaj +1 more source
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley +1 more source
Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee +5 more
wiley +1 more source

