Results 121 to 130 of about 394,345 (286)

Misconception of High School Students on Acid-Base Topics and Effectiveness of Argument-Driven Inquiry Learning Model as an Effort to Improve Misconception

open access: yesJurnal Pendidikan Sains, 2019
: The objectives of this study were: 1) calculate the average percent of students in each sub-topic on the pretest, posttest, and delay test, 2) identify students’ misconceptions in acid-base topic, 3) test the effectiveness of the ADI learning model in ...
Anjamputra A. Embisa   +2 more
doaj   +1 more source

Warren J. Samuels (1933-2011) [PDF]

open access: yes, 2012
This paper examines the research and career of the late Warren J. Samuels (1933-2011), an influential institutionalist economist in the Wisconsin John Commons tradition and well-known historian and methodologist of economics.
Davis, John B.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Pros and Cons of Politically Reversible Semisubstantive Constitutional Rules [PDF]

open access: yes, 2009
Most observers of constitutional adjudication believe that it works in an all-or-nothing way. On this view, the substance of challenged rules is of decisive importance, so that political decision makers may resuscitate invalidated laws only by way of ...
Coenen, Dan T.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Ellipsis, economy, and the (non)uniformity of traces [PDF]

open access: yes, 2016
A number of works have attempted to account for the interaction between movement and ellipsis in terms of an economy condition Max- Elide. We show that the elimination of MaxElide leads to an empirically superior account of these interactions.
Messick, Troy, Thoms, Gary
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Research Trends in Argumentation Skills in Indonesian Science Education: A Systematic Review of Models, Subjects, and Learning Topics

open access: yesIndonesian Journal of Educational Research and Review
Argumentation skills are one of the important competencies of the 21st century that play a role in building conceptual understanding and critical thinking skills.
Umi Kalsum Djano   +3 more
doaj   +3 more sources

Thought experiments in current metaphilosophical debates [PDF]

open access: yes, 2018
Although thought experiments were first discovered as a sui generis methodological tool by philosophers of science (most prominently by Ernst Mach), the tool can also be found – even more frequently – in contemporary philosophy.
Cohnitz, Daniel, Häggqvist, Sören
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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