Results 101 to 110 of about 19,818 (290)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

An Examination of the Use of Argument Driven Inquiry Strategies to Support Argumentative Writing in the Middle School Science Classroom

, 2021
The purpose of this study was to explore the impact that argument driven inquiry strategies would have on the written ability of seventh grade science students.
Barrie, Michele
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Inquiry research trends through bibliometric analysis (2020-2023)

Biosfer
This article aims to analyze the trend of Inquiry research through bibliometrics in the Google schoolar database from 2020 to 2023. The article consists of a total of 993 articles, then sorted into 788 suitable articles and analyzed.
Lilis Lismaya, Wiyanto Wiyanto, Saiful Ridlo   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Pengaruh Argument-Driven Inquiry Terhadap Kesadaran Metakognisi dan Hasil Belajar Kognitif Siswa SMP

, 2019
This study aims to determine the significance of the effect of Argument-Driven Inquiry’s learning model on metacognition awareness and cognitive learning outcomes of students in the subject matter of the respiratory system.
Prastio, Uji Yoga, Hasnunidah, Neni
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Misconception of High School Students on Acid-Base Topics and Effectiveness of Argument-Driven Inquiry Learning Model as an Effort to Improve Misconception

Jurnal Pendidikan Sains, 2019
: The objectives of this study were: 1) calculate the average percent of students in each sub-topic on the pretest, posttest, and delay test, 2) identify students’ misconceptions in acid-base topic, 3) test the effectiveness of the ADI learning model in ...
Anjamputra A. Embisa, Subandi Subandi, Fauziatul Fajaroh   +2 more
doaj   +1 more source