Structures of designed armadillo repeat proteins binding to peptides fused to globular domains [PDF]
Protein Science, 2017 AbstractDesigned armadillo repeat proteins (dArmRP) are α‐helical solenoid repeat proteins with an extended peptide binding groove that were engineered to develop a generic modular technology for peptide recognition. In this context, the term “peptide” not only denotes a short unstructured chain of amino acids, but also an unstructured region of a ...
Chaithanya Madhurantakam +2 more
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Frontiers in Plant Science, 2014 Post-translational protein modification plays a pivotal role in the regulation and specific turnover of proteins. One of these important modifications is the ubiquitination of target proteins, which can occur at distinct cellular compartments.
Katja eVogelmann +6 more
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Exploring the roles of ZmARM gene family in maize development and abiotic stress response [PDF]
PeerJ, 2023 Armadillo (ARM) was a gene family important to plants, with crucial roles in regulating plant growth, development, and stress responses. However, the properties and functions of ARM family members in maize had received limited attention.
Zhijia Yu +7 more
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iScience, 2022 Summary: The mitogen-activated protein kinase (MAPK) intracellular signaling pathway mediates numerous biological processes, including antimicrobial immune response by inducing antimicrobial peptides (AMPs) production.
Jude Juventus Aweya +9 more
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ARMC Subfamily: Structures, Functions, Evolutions, Interactions, and Diseases
Frontiers in Molecular Biosciences, 2021 Armadillo repeat-containing proteins (ARMCs) are widely distributed in eukaryotes and have important influences on cell adhesion, signal transduction, mitochondrial function regulation, tumorigenesis, and other processes.
Yutao Huang +8 more
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Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development. [PDF]
PLoS ONE, 2012 A subset of signaling pathways play exceptionally important roles in embryonic and post-embryonic development, and mis-regulation of these pathways occurs in most human cancers. One such pathway is the Wnt pathway.
David M Roberts +8 more
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An armadillo-domain protein participates in a telomerase interaction network [PDF]
Plant Molecular Biology, 2018 Arabidopsis and human ARM protein interact with telomerase. Deregulated mRNA levels of DNA repair and ribosomal protein genes in an Arabidopsis arm mutant suggest non-telomeric ARM function. The human homolog ARMC6 interacts with hTRF2. Telomerase maintains telomeres and has proposed non-telomeric functions.
Ladislav Dokládal +6 more
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Epsin 1 Undergoes Nucleocytosolic Shuttling and Its Eps15 Interactor Nh2-Terminal Homology (Enth) Domain, Structurally Similar to Armadillo and Heat Repeats, Interacts with the Transcription Factor Promyelocytic Leukemia Zn2+ Finger Protein (Plzf) [PDF]
The Journal of Cell Biology, 2000 Epsin (Eps15 interactor) is a cytosolic protein involved in clathrin-mediated endocytosis via its direct interactions with clathrin, the clathrin adaptor AP-2, and Eps15. The NH2-terminal portion of epsin contains a phylogenetically conserved module of unknown function, known as the ENTH domain (epsin NH2-terminal homology domain).
J. Hyman +4 more
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Tandem-repeat protein domains across the tree of life [PDF]
PeerJ, 2015 Tandem-repeat protein domains, composed of repeated units of conserved stretches of 20–40 amino acids, are required for a wide array of biological functions.
Kristin K. Jernigan, Seth R. Bordenstein
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Flotillins directly interact with γ-catenin and regulate epithelial cell-cell adhesion. [PDF]
PLoS ONE, 2013 Flotillin-1 and flotillin-2 are two homologous, membrane raft associated proteins. Although it has been reported that flotillins are involved in cell adhesion processes and play a role during breast cancer progression, thus making them interesting future
Nina Kurrle +5 more
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