Results 1 to 10 of about 8,647 (121)
Exploring the roles of ZmARM gene family in maize development and abiotic stress response [PDF]
PeerJ, 2023 Armadillo (ARM) was a gene family important to plants, with crucial roles in regulating plant growth, development, and stress responses. However, the properties and functions of ARM family members in maize had received limited attention.
Zhijia Yu +7 more
doaj +2 more sources
iScience, 2022 Summary: The mitogen-activated protein kinase (MAPK) intracellular signaling pathway mediates numerous biological processes, including antimicrobial immune response by inducing antimicrobial peptides (AMPs) production.
Jude Juventus Aweya +9 more
doaj +1 more source
ARMC Subfamily: Structures, Functions, Evolutions, Interactions, and Diseases
Frontiers in Molecular Biosciences, 2021 Armadillo repeat-containing proteins (ARMCs) are widely distributed in eukaryotes and have important influences on cell adhesion, signal transduction, mitochondrial function regulation, tumorigenesis, and other processes.
Yutao Huang +8 more
doaj +1 more source
Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development. [PDF]
PLoS ONE, 2012 A subset of signaling pathways play exceptionally important roles in embryonic and post-embryonic development, and mis-regulation of these pathways occurs in most human cancers. One such pathway is the Wnt pathway.
David M Roberts +8 more
doaj +1 more source
Tandem-repeat protein domains across the tree of life [PDF]
PeerJ, 2015 Tandem-repeat protein domains, composed of repeated units of conserved stretches of 20–40 amino acids, are required for a wide array of biological functions.
Kristin K. Jernigan, Seth R. Bordenstein
doaj +2 more sources
Flotillins directly interact with γ-catenin and regulate epithelial cell-cell adhesion. [PDF]
PLoS ONE, 2013 Flotillin-1 and flotillin-2 are two homologous, membrane raft associated proteins. Although it has been reported that flotillins are involved in cell adhesion processes and play a role during breast cancer progression, thus making them interesting future
Nina Kurrle +5 more
doaj +1 more source
A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
eLife, 2022 Activating mutations in the leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease, and previously we showed that activated LRRK2 phosphorylates a subset of Rab GTPases (Steger et al., 2017).
Edmundo G Vides +10 more
doaj +1 more source
Functional and genomic analyses of alpha-solenoid proteins. [PDF]
PLoS ONE, 2013 Alpha-solenoids are flexible protein structural domains formed by ensembles of alpha-helical repeats (Armadillo and HEAT repeats among others). While homology can be used to detect many of these repeats, some alpha-solenoids have very little sequence ...
David Fournier +6 more
doaj +1 more source
Biology Direct, 2017 The protein Gcn1 (General control non-derepressible 1) is found in virtually all eukaryotes, and is a key component of the general amino acid control signal transduction pathway.
Ramachandran Rakesh +3 more
doaj +1 more source
Aristaless Related Homeobox (ARX) Interacts with β-Catenin, BCL9, and P300 to Regulate Canonical Wnt Signaling. [PDF]
PLoS ONE, 2017 Mutations in the Aristaless Related Homeobox (ARX) gene are associated with a spectrum of structural (lissencephaly) and functional (epilepsy and intellectual disabilities) neurodevelopmental disorders.
Il-Taeg Cho +3 more
doaj +1 more source