Results 21 to 30 of about 8,696 (131)

Hsp70-nucleotide exchange factor (NEF) Fes1 has non-NEF roles in degradation of gluconeogenic enzymes and cell wall integrity.

PLoS Genetics, 2019
Fes1 is a conserved armadillo repeat-containing Hsp70 nucleotide exchange factor important for growth at high temperature, proteasomal protein degradation and prion propagation.
Shailesh Kumar, Daniel C Masison
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A Lotus japonicus E3 ligase interacts with the Nod Factor Receptor 5 and positively regulates nodulation

BMC Plant Biology, 2018
Background Post-translational modification of receptor proteins is involved in activation and de-activation of signalling systems in plants. Both ubiquitination and deubiquitination have been implicated in plant interactions with pathogens and symbionts.
Daniela Tsikou, Estrella E. Ramirez, Ioanna S. Psarrakou, Jaslyn E. Wong, Dorthe B. Jensen, Erika Isono, Simona Radutoiu, Kalliope K. Papadopoulou   +7 more
doaj   +1 more source

Opposing roles of Fos, Raw, and SARM1 in the regulation of axonal degeneration and synaptic structure

Frontiers in Cellular Neuroscience, 2023
IntroductionThe degeneration of injured axons is driven by conserved molecules, including the sterile armadillo TIR domain-containing protein SARM1, the cJun N-terminal kinase JNK, and regulators of these proteins.
Thomas J. Waller, Catherine A. Collins, Catherine A. Collins   +2 more
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The Interaction of FABP with Kapα. [PDF]

PLoS ONE, 2015
Gene-activating lipophilic compounds are carried into the nucleus when loaded on fatty-acid-binding proteins (FABP). Some of these proteins are recognized by the α-Karyopherin (Kapα) through its nuclear localization signal (NLS) consisting of three ...
Ortal Amber-Vitos, Nataly Kucherenko, Esther Nachliel, Menachem Gutman, Yossi Tsfadia   +4 more
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Deciphering the evolution of composite-type GSKIP in mitochondria and Wnt signaling pathways.

PLoS ONE, 2022
We previously revealed the origin of mammalian simple-type glycogen synthase kinase interaction protein (GSKIP), which served as a scavenger and a competitor in the Wnt signaling pathway during evolution.
Cheng-Yu Tsai, Shean-Jaw Chiou, Huey-Jiun Ko, Yu-Fan Cheng, Sin-Yi Lin, Yun-Ling Lai, Chen-Yen Lin, Chihuei Wang, Jiin-Tsuey Cheng, Hsin-Fu Liu, Aij-Li Kwan, Joon-Khim Loh, Yi-Ren Hong   +12 more
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δ-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles

Molecular Cancer, 2009
Background δ-Catenin is a unique member of β-catenin/armadillo domain superfamily proteins and its primary expression is restricted to the brain. However, δ-catenin is upregulated in human prostatic adenocarcinomas, although the effects of δ-catenin ...
Chen Yan-Hua, Wang Tao, Lu Jian-Ping, Abdallah Agustin, Zeng Yan, Terrian David M, Kim Kwonseop, Lu Qun   +7 more
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Unveiling the Binding between the Armadillo-Repeat Domain of Plakophilin 1 and the Intrinsically Disordered Transcriptional Repressor RYBP

Biomolecules
Plakophilin 1 (PKP1), a member of the p120ctn subfamily of the armadillo (ARM)-repeat-containing proteins, is an important structural component of cell–cell adhesion scaffolds although it can also be ubiquitously found in the cytoplasm and the nucleus ...
Salome Araujo-Abad, Bruno Rizzuti, Miguel Vidal, Olga Abian, María Esther Fárez-Vidal, Adrian Velazquez-Campoy, Camino de Juan Romero, José L. Neira   +7 more
doaj   +1 more source

Structural characterization of human importin alpha 7 in its cargo-free form at 2.5 Å resolution

Scientific Reports, 2022
Shuttling of macromolecules between nucleus and cytoplasm is a tightly regulated process mediated through specific interactions between cargo and nuclear transport proteins.
S. Tsimbalyuk, C. M. Donnelly, J. K. Forwood   +2 more
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A motif within the armadillo repeat of Parkinson’s-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway

Scientific Reports, 2018
In experimental models, both in vivo and cellular, over-expression of Parkinson’s linked mutant leucine-rich repeat kinase 2 (LRRK2) is sufficient to induce neuronal death. While several cell death associated proteins have been linked to LRRK2, either as
Nasia Antoniou, Dimitrios Vlachakis, Anna Memou, Emmanouela Leandrou, Polytimi-Eleni Valkimadi, Katerina Melachroinou, Diane B. Re, Serge Przedborski, William T. Dauer, Leonidas Stefanis, Hardy J. Rideout   +10 more
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EFR3A, an Intriguing Gene, and Protein with a Scaffolding Function

Cells
The EFR3 (Eighty-Five Requiring 3) protein and its homologs are rather poorly understood eukaryotic plasma membrane peripheral proteins. They belong to the armadillo-like family of superhelical proteins.
Magdalena Trybus, Anita Hryniewicz-Jankowska, Aleksander Czogalla, Aleksander F. Sikorski   +3 more
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