Results 31 to 40 of about 15,999 (168)

ConSole: using modularity of contact maps to locate solenoid domains in protein structures. [PDF]

, 2014
BackgroundPeriodic proteins, characterized by the presence of multiple repeats of short motifs, form an interesting and seldom-studied group. Due to often extreme divergence in sequence, detection and analysis of such motifs is performed more reliably on
Godzik, Adam, Hrabe, Thomas
core   +4 more sources

A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain. [PDF]

PLoS ONE, 2017
Porphyromonas gingivalis, an asaccharolytic Gram-negative oral anaerobe, is a major pathogen associated with adult periodontitis, a chronic infective disease that a significant percentage of the human population suffers from.
Altijana Hromić-Jahjefendić, Nina Jajčanin Jozić, Saša Kazazić, Marina Grabar Branilović, Zrinka Karačić, Jörg H Schrittwieser, Krishna Mohan Padmanabha Das, Marko Tomin, Monika Oberer, Karl Gruber, Marija Abramić, Sanja Tomić   +11 more
doaj   +1 more source

Hsp70-nucleotide exchange factor (NEF) Fes1 has non-NEF roles in degradation of gluconeogenic enzymes and cell wall integrity.

PLoS Genetics, 2019
Fes1 is a conserved armadillo repeat-containing Hsp70 nucleotide exchange factor important for growth at high temperature, proteasomal protein degradation and prion propagation.
Shailesh Kumar, Daniel C Masison
doaj   +1 more source

A Lotus japonicus E3 ligase interacts with the Nod Factor Receptor 5 and positively regulates nodulation

BMC Plant Biology, 2018
Background Post-translational modification of receptor proteins is involved in activation and de-activation of signalling systems in plants. Both ubiquitination and deubiquitination have been implicated in plant interactions with pathogens and symbionts.
Daniela Tsikou, Estrella E. Ramirez, Ioanna S. Psarrakou, Jaslyn E. Wong, Dorthe B. Jensen, Erika Isono, Simona Radutoiu, Kalliope K. Papadopoulou   +7 more
doaj   +1 more source

Opposing roles of Fos, Raw, and SARM1 in the regulation of axonal degeneration and synaptic structure

Frontiers in Cellular Neuroscience, 2023
IntroductionThe degeneration of injured axons is driven by conserved molecules, including the sterile armadillo TIR domain-containing protein SARM1, the cJun N-terminal kinase JNK, and regulators of these proteins.
Thomas J. Waller, Catherine A. Collins, Catherine A. Collins   +2 more
doaj   +1 more source

Ltc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts. [PDF]

, 2015
Organelle contact sites perform fundamental functions in cells, including lipid and ion homeostasis, membrane dynamics, and signaling. Using a forward proteomics approach in yeast, we identified new ER-mitochondria and ER-vacuole contacts specified by an
Murley, Andrew, Nunnari, Jodi, Prinz, William A, Sarsam, Reta D, Toulmay, Alexandre, Yamada, Justin   +5 more
core   +2 more sources

Plasma membrane-association of SAUL1-type plant U-box armadillo repeat proteins is conserved in land plants

Frontiers in Plant Science, 2014
Post-translational protein modification plays a pivotal role in the regulation and specific turnover of proteins. One of these important modifications is the ubiquitination of target proteins, which can occur at distinct cellular compartments.
Katja eVogelmann, Christa eSubert, Nina eDanzberger, Gabriele eDrechsel, Johannes eBergler, Thorsten eBurmester, Stefan eHoth   +6 more
doaj   +1 more source

The Interaction of FABP with Kapα. [PDF]

PLoS ONE, 2015
Gene-activating lipophilic compounds are carried into the nucleus when loaded on fatty-acid-binding proteins (FABP). Some of these proteins are recognized by the α-Karyopherin (Kapα) through its nuclear localization signal (NLS) consisting of three ...
Ortal Amber-Vitos, Nataly Kucherenko, Esther Nachliel, Menachem Gutman, Yossi Tsfadia   +4 more
doaj   +1 more source

Deciphering the evolution of composite-type GSKIP in mitochondria and Wnt signaling pathways.

PLoS ONE, 2022
We previously revealed the origin of mammalian simple-type glycogen synthase kinase interaction protein (GSKIP), which served as a scavenger and a competitor in the Wnt signaling pathway during evolution.
Cheng-Yu Tsai, Shean-Jaw Chiou, Huey-Jiun Ko, Yu-Fan Cheng, Sin-Yi Lin, Yun-Ling Lai, Chen-Yen Lin, Chihuei Wang, Jiin-Tsuey Cheng, Hsin-Fu Liu, Aij-Li Kwan, Joon-Khim Loh, Yi-Ren Hong   +12 more
doaj   +1 more source

Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm [PDF]

, 2013
Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous ciliopathy disorder affecting cilia and sperm motility. A range of ultrastructural defects of the axoneme underlie the disease, which is characterised by chronic respiratory symptoms ...
Alexandros Onoufriadis, Amelia Shoemark, Anthony T Moore, Antony, Bush, Chela T James, Chiara Bacchelli, Claire Hogg, Eddie M K Chung, Elisabeth M Rosser, Fliegauf, Gerard Pals, Gherman, Hannah M Mitchison, Hirst, Hjeij, Hozumi, Jeannette E Danke-Roelse, John J Sloper, Kennedy, Knowles, Loges, Lonergan, Miriam Schmidts, Mitali Patel, Mustafa M Munye, O'Toole, Olbrich, Ong, Onoufriadis, Papon, Peter J Scambler, Philip L Beales, Plagnol, Richard D Emes, Roy, Sarah Hull, Schultz, Shoemark, Speder, Stephen L Hart, Tarkar, Tewari, Xu, Yang, Zhang   +45 more
core   +3 more sources