Results 51 to 60 of about 9,699 (146)

Steroid profiling in preeclamptic women: evidence for aromatase deficiency

American Journal of Obstetrics and Gynecology, 2010
Experimental data have revealed the critical role played by 2-methoxy-estradiol, a metabolite of 17β-estradiol, in the pathophysiology of preeclampsia. We used gas chromatography/mass spectrometry to measure a whole panel of hormonal steroids in the plasma from women during the third trimester of their pregnancy.The population study consists of 24 ...
Hertig, Alexandre, Liere, Philippe, Chabbert-Buffet, Nathalie, Fort, Julie, Pianos, Antoine, Eychenne, Bernard, Cambourg, Annie, Schumacher, Michael, Berkane, Nadia, Lefevre, Guillaume, Uzan, Serge, Rondeau, Eric, Rozenberg, Patrick, Rafestin-Oblin, Marie-Edith   +13 more
openaire   +3 more sources

Treatment-Induced Bone Loss and Fractures in Cancer Patients Undergoing Hormone Ablation Therapy: Efficacy and Safety of Denosumab

Clinical Medicine Insights: Oncology, 2012
Hormone ablation therapy (HALT) for breast or prostate cancer accelerates the development of osteoporosis in both men and women by causing estrogen deficiency, which increases the risk for fracture by promoting bone resorption mediated by osteoclasts ...
Allan Lipton, Matthew R. Smith, Georgiana K. Ellis, Carsten Goessl   +3 more
doaj   +1 more source

A child with hypertension and ambiguous genitalia – an uncommon variant of congenital adrenal hyperplasia: a case report

Journal of Medical Case Reports, 2017
Background Deficiency in 11β-hydroxylase as a cause of congenital adrenal hyperplasia is uncommon. It should be considered in the differential diagnosis of hypertension with virilization in any prepubescent child.
Vivek Pant, Suman Baral, Bishal Shrestha, Arjun Tumbapo   +3 more
doaj   +1 more source

The low density lipoprotein receptor modulates the effects of hypogonadism on diet-induced obesity and related metabolic perturbations

Journal of Lipid Research, 2014
Here, we investigated how LDL receptor deficiency (Ldlr−/−) modulates the effects of testosterone on obesity and related metabolic dysfunctions. Though sham-operated Ldlr−/− mice fed Western-type diet for 12 weeks became obese and showed disturbed plasma
Caterina Constantinou, Diogenis Mpatsoulis, Anastasios Natsos, Peristera-Ioanna Petropoulou, Evangelia Zvintzou, Abdulmaged M. Traish, Peter J. Voshol, Iordanes Karagiannides, Kyriakos E. Kypreos   +8 more
doaj   +1 more source

Effect of estrogens on sex-specific influence in sleep deprivation in mice

Brain Research Bulletin
Men and women generally exhibit different sleep patterns and structures. These differences also extend to how each sex responds to sleep deprivation, a condition linked to various health issues.
Qi Deng, Yuhong Li, Zuoli Sun, Xue Fenqin, Xiang Gao, Rena Li   +5 more
doaj   +1 more source

Lack of 17β-estradiol reduces sensitivity to insulin in the liver and muscle of male mice

Heliyon, 2018
The importance of estrogens for glucose homeostasis has been demonstrated by clinical, pharmacological, and experimental studies. Male mice lacking the aromatase gene (ArKO mice), which encodes an enzyme involved in estrogen synthesis, develop glucose ...
Katsumi Toda, Akiko Toda, Masafumi Ono, Toshiji Saibara   +3 more
doaj   +1 more source

Aromatase deficiency caused by mutation of CYP19A1 gene: A case report. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2022
Li H, Fu S, Dai R, Sheng Z, Liu W.
europepmc   +1 more source

A Novel Mouse Model of Alzheimer's Disease with Chronic Estrogen Deficiency Leads to Glial Cell Activation and Hypertrophy

Journal of Aging Research, 2011
The role of estrogens in Alzheimer's disease (AD) involving β-amyloid (Aβ) generation and plaque formation was mostly tested in ovariectomized mice with or without APP mutations.
Annik Prat, Maik Behrendt, Edwige Marcinkiewicz, Sebastien Boridy, Ram M. Sairam, Nabil G. Seidah, Dusica Maysinger   +6 more
doaj   +1 more source

Review paper
Cardiovascular and metabolic effects of estrogen in men

Archives of Medical Science, 2006
Although in men with an inherited mutation of gene encoding ERa (estrogen resistance) the occurrence of premature coronary artery disease was documented, and in men with inherited lack of aromatase (estrogen deficiency) an unfavorable lipid milieu was ...
Jerzy Krzysztof Wranicz, Iwona Cygankiewicz, Piotr Kula, Renata Walczak-Jędrzejowska, Jolanta Słowikowska-Hilczer, Krzysztof Kula   +5 more
doaj  

Steroid hormone-deprived sex reversal in cyp11a1 mutant XX tilapia experiences an ovary-like stage at molecular level

Communications Biology
Fish sex is largely influenced by steroid hormones, especially sex hormones. Here, we established a steroid hormone-free genetic model by mutation of cyp11a1 in Nile tilapia, which was confirmed by EIA assay.
Hesheng Xiao, Leihui Wang, Shuo Yan, He Ma, Zhen Xu, Feilong Wang, Jingrong Wang, Wenjing Tao, Deshou Wang   +8 more
doaj   +1 more source