Results 31 to 40 of about 9,699 (146)

Endogenous Estrogen Influences Predator Odor-Induced Impairment of Cognitive and Social Behaviors in Aromatase Gene Deficiency Mice

Behavioural Neurology, 2021
Epidemiological studies have suggested that traumatic stress increases vulnerability to various mental disorders, such as dementia and psychiatric disorders.
Yaner Gao, Lei Ma, Feng Gao, Zuoli Sun, Zhengrong Zhang, Yuhong Li, Rena Li   +6 more
doaj   +1 more source

Estrogen/androgen balance in men with hyperestrogenism normalized by using letrozole of the aromatase inhibitor drug class

Акушерство, гинекология и репродукция, 2022
Introduction. Currently, virtually no data on comparative studies of efficacy and safety of drug class aromatase inhibitors vs. standard therapies used in patients with overweight and/or obesity with an initial testosterone deficiency and excessive ...
Z. Sh. Pavlova, A. S. Ametov, I. I. Golodnikov, A. A. Kamalov   +3 more
doaj   +1 more source

Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia

PLOS ONE, 2015
Preeclampsia is a maternal hypertensive disorder with uncertain etiology and a leading cause of maternal and fetal mortality worldwide, causing nearly 40% of premature births delivered before 35 weeks of gestation. The first stage of preeclampsia is characterized by reduction of utero-placental blood flow which is reflected in high blood pressure and ...
Alejandra Perez-Sepulveda, Lara J Monteiro, Aneta Dobierzewska, Pedro P España-Perrot, Pía Venegas-Araneda, Alejandra M Guzmán-Rojas, María I González, Macarena Palominos-Rivera, Carlos E Irarrazabal, Horacio Figueroa-Diesel, Manuel Varas-Godoy, Sebastián E Illanes   +11 more
openaire   +7 more sources

Serotonin transporter deficiency drives estrogen-dependent obesity and glucose intolerance

Scientific Reports, 2017
Depression and use of antidepressant medications are both associated with increased risk of obesity, potentially attributed to a reduced serotonin transporter (SERT) function. However, how SERT deficiency promotes obesity is unknown.
Weibin Zha, Horace T. B. Ho, Tao Hu, Mary F. Hebert, Joanne Wang   +4 more
doaj   +1 more source

Sex Steroids and Bone Health Status in Men

International Journal of Endocrinology, 2012
Male osteoporosis is a health problem which deserves more attention as nearly 30% of osteoporotic fractures happen in men aged 50 years and above.
Kok-Yong Chin, Soelaiman Ima-Nirwana
doaj   +1 more source

Long-term follow-up of a female with congenital adrenal hyperplasia due to P450-oxidoreductase deficiency

Archives of Endocrinology and Metabolism, 2016
SUMMARY P450 oxidoreductase deficiency (PORD) is a variant of congenital adrenal hyperplasia that is caused by POR gene mutations. The POR gene encodes a flavor protein that transfers electrons from nicotinamide adenine dinucleotide phosphate (NADPH) to ...
Beatriz D. S. F. Bonamichi, Stella L. M. Santiago, Débora R. Bertola, Chong A. Kim, Nivaldo Alonso, Berenice B. Mendonca, Tania A. S. S. Bachega, Larissa G. Gomes   +7 more
doaj   +1 more source

The Utilization and Impact of Aromatase Inhibitor Therapy in Men With Elevated Estradiol Levels on Testosterone Therapy

Sexual Medicine, 2021
: Introduction: Testosterone therapy (TTH) for testosterone deficiency (TD) may lead to elevated estradiol (E2) levels requiring management to avoid unnecessary adverse effects.
Nahid Punjani, MD, MPH, Helen Bernie, DO, Carolyn Salter, MD, Jose Flores, MD, Nicole Benfante, BS, John P. Mulhall, MD, MSc, FECSM, FACS   +5 more
doaj   +1 more source

Bone Has a Sexually Dimorphic Response to Aromatase Deficiency [PDF]

Journal of Bone and Mineral Research, 2000
Abstract Aromatase synthesizes estrogen from androgen precursors. To better understand the role of estrogen in skeletal metabolism and growth, we have assessed long bone growth and histomorphometry in aromatase-deficient (ArKO) mice. The age range for the animals was 5–7 months.
O K, Oz, J E, Zerwekh, C, Fisher, K, Graves, L, Nanu, R, Millsaps, E R, Simpson   +6 more
openaire   +2 more sources

Endocrinological aspects of dietary habits

Czech Journal of Food Sciences, 2004
Dietary habits reflect both the recent economic possibilities and the cultural history of individual human populations. They may influence endocrine systems and thus affect the health of the respective populations in several manners: (1) People consuming
O. Lapčík
doaj   +1 more source

Virilization in a pregnancy

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2012
We describe a 29-year old pregnant woman with history of primary hypothyroidism and impaired glucose tolerance presenting in her third trimester with preeclampsia and virilization.
M W Niranjala, C N Wijeyaratne, G K C Jayalath   +2 more
doaj   +1 more source