Results 41 to 50 of about 9,699 (146)

Daily supplement of sesame oil prevents postmenopausal osteoporosis via maintaining serum estrogen and aromatase levels in rats

Scientific Reports
Estrogen deficiency is one of the main causes of postmenopausal osteoporosis in elderly women. Hormone replacement therapy has been employed to manage postmenopausal osteoporosis; however, it has raised concerns related to heart attacks and breast cancer.
Che-Chia Hsu, Po-Yen Ko, Ting-Hsien Kwan, Ming-Yie Liu, I.-Ming Jou, Chi-Wei Lin, Po-Ting Wu   +6 more
doaj   +1 more source

A case report supporting the concept that a role for the anti-Müllerian hormone (AMH) in normal folliculogenesis is to diminish the biological activity of follicle stimulating hormone (FSH)

Clinical and Experimental Obstetrics & Gynecology, 2020
Purpose: To describe a case where a woman was ovulating with regular menses despite very low sera follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels.
J.H. Check, E. Chang, R. Cohen
doaj   +1 more source

Testosterone Replacement Attenuates Haloperidol-Induced Catalepsy in Male Rats

Advanced Pharmaceutical Bulletin, 2014
Purpose: Parkinson’s disease (PD) is a progressive neurodegenerative disease. Recent studies have indicated a higher prevalence of PD in male gender. Furthermore testosterone deficiency is more common among male parkinsonians in compare to healthy men ...
Naime Majidi Zolbanin, Elmira Zolali, Alireza Mohajjel Nayebi   +2 more
doaj   +1 more source

Genetic evidence for differential functions of figla and nobox in zebrafish ovarian differentiation and folliculogenesis

Communications Biology, 2023
FIGLA and NOBOX are important oocyte-specific transcription factors. Both figla-/- and nobox-/- mutants showed all-male phenotype in zebrafish due to increased dominance of the male-promoting pathway.
Kun Wu, Yue Zhai, Mingming Qin, Cheng Zhao, Nana Ai, Jianguo He, Wei Ge   +6 more
doaj   +1 more source

Aromatase Deficiency Inhibits the Permeability Transition in Mouse Liver Mitochondria [PDF]

Endocrinology, 2010
Lack of estrogens affects male physiology in a number of ways, including severe changes in liver metabolism that result in lipid accumulation and massive hepatic steatosis. Here we investigated whether estrogen deficiency may alter the functionality and permeability properties of liver mitochondria using, as an experimental model, aromatase knockout ...
Moro, Loredana, Arbini, Arnaldo A., Hsieh, Jer-Tsong, Ford, Jeffery, Simpson, Evan R., Hajibeigi, Asghar, Öz, Orhan K.   +6 more
openaire   +2 more sources

Androgen receptor alpha deficiency impacts aromatase expression in the female cichlid brain

Royal Society Open Science
Steroid hormones bind to specific receptors that act as transcription factors to modify gene expression in the brain to regulate physiological and behavioural processes.
Mariana S. Lopez, Beau A. Alward
doaj   +1 more source

Recent advancement in the treatment of boys and adolescents with hypogonadism

Therapeutic Advances in Endocrinology and Metabolism, 2022
Clinical manifestations and the need for treatment varies according to age in males with hypogonadism. Early foetal-onset hypogonadism results in disorders of sex development (DSD) presenting with undervirilised genitalia whereas hypogonadism established
Rodolfo A. Rey
doaj   +1 more source

Loss of vitamin D receptor induces premature ovarian insufficiency through compromising the 7-dehydrocholesterol-dependent anti-aging effects

Frontiers in Cell and Developmental Biology
Vitamin D has the potential to therapeutically affect the endocrine parameters of premature ovarian insufficiency (POI) patients. Previous research has indicated that serum vitamin D levels tend to decline with age and in individuals with POI.
Haiyun Chen, Qiuyi Wang, Yi Zhang, Luxi Shangguan, Zhengquan Zhu, Huan Zhang, Xiang Zou, Qinghe Geng, Qinghe Geng, Yanting Wen, Daojuan Wang, Yong Wang, Yong Wang   +12 more
doaj   +1 more source

The role of vitamin D in breast cancer

Oncology Reviews, 2011
The biological role of vitamin D outside of calcium homeostasis is still under evaluation. The ability of vitamin D to inhibit cell proliferation and induce differentiation makes it a potential modifier of neoplastic transformation. Vitamin D affects the
Tu Tu Aung, Sreenivasa R. Chandana, Karl J. D’Silva, Nikolay V. Dimitrov   +3 more
doaj   +1 more source

Flavonoid glycosides isolated from Epimedium brevicornum and their estrogen biosynthesis-promoting effects

Scientific Reports, 2017
Epimedium brevicornum Maxim has a long history of use in the treatment of estrogen deficiency-related diseases. However, the chemical constituents and mechanism of action of this medicinal plant are not fully understood. In the present study, we isolated
Fu Li, Bao-Wen Du, Dan-Feng Lu, Wen-Xuan Wu, Kanjana Wongkrajang, Lun Wang, Wen-Chen Pu, Chang-Lu Liu, Han-Wei Liu, Ming-Kui Wang, Fei Wang   +10 more
doaj   +1 more source