Results 61 to 70 of about 438,768 (166)

Assessment and management of dyspareunia in peri‐ and postmenopausal women: A phenotype‐based gynecologic approach

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul, Marcel Vančo, Jaroslava Banýrová, Aneta Hujová   +3 more
wiley   +1 more source

Androgen receptor alpha deficiency impacts aromatase expression in the female cichlid brain

Royal Society Open Science
Steroid hormones bind to specific receptors that act as transcription factors to modify gene expression in the brain to regulate physiological and behavioural processes.
Mariana S. Lopez, Beau A. Alward
doaj   +1 more source

Sexuality in a man with aromatase deficiency

, 1998
The evaluation of sexual behavior in a man with aromatase deficiency explains the role of estrogen on male sexuality.
Antonio R. M. Granata, ROCHIRA, Vincenzo, Antonio Balestrieri, Monica Bevini, CARANI, Cesare   +4 more
core  

Loss of vitamin D receptor induces premature ovarian insufficiency through compromising the 7-dehydrocholesterol-dependent anti-aging effects

Frontiers in Cell and Developmental Biology
Vitamin D has the potential to therapeutically affect the endocrine parameters of premature ovarian insufficiency (POI) patients. Previous research has indicated that serum vitamin D levels tend to decline with age and in individuals with POI.
Haiyun Chen, Qiuyi Wang, Yi Zhang, Luxi Shangguan, Zhengquan Zhu, Huan Zhang, Xiang Zou, Qinghe Geng, Qinghe Geng, Yanting Wen, Daojuan Wang, Yong Wang, Yong Wang   +12 more
doaj   +1 more source

The role of vitamin D in breast cancer

Oncology Reviews, 2011
The biological role of vitamin D outside of calcium homeostasis is still under evaluation. The ability of vitamin D to inhibit cell proliferation and induce differentiation makes it a potential modifier of neoplastic transformation. Vitamin D affects the
Tu Tu Aung, Sreenivasa R. Chandana, Karl J. D’Silva, Nikolay V. Dimitrov   +3 more
doaj   +1 more source

Bone radiological findings in a man affected by aromatase deficiency treated with estrogens

, 1998
Estrogen replacemente treatment in a man affected by aromatase deficiency changes bone radiological aspects leading to a fusion of the epiphyses of long bones, the latter was not achieved with the treatment of testosterone ...
Marco Faustini Fustini, ROCHIRA, Vincenzo, Antonio Balestrieri, Vincenzo Spina, CARANI, Cesare   +4 more
core  

Conserved SERPINE2 function maintains ovarian estrogen production to support fertility in goats and mice

iMetaOmics, EarlyView.
Single‐nucleus RNA sequencing and functional profiling of goat ovaries with divergent litter sizes revealed prolificacy‐associated granulosa cell (GC) states characterized by enhanced proliferation‐ and steroidogenesis‐related features, together with altered predicted cell–cell communication.
Sanbao Zhang, Yirong Wei, Xiaoping Guo, Ruimen Zhang, Yingming Wei, Yanna Huang, Qinyang Jiang   +6 more
wiley   +1 more source

Congenital aromatase deficiency in an adult male: A case report of clinical course and symptom reversal with estrogen supplementation

Urology Case Reports
Congenital aromatase deficiency is an autosomal recessive CYP19A1 loss-of-function disorder that blocks conversion of androgens to estrogens. A man with homozygous CYP19A1 c.628G > A (exon 5) presented with longstanding fatigue, low libido, and desire to
Peyton Coady, Arnaav Walia, Beatriz Hernandez, David E. Hinojosa-Gonzalez, Adnan El-Achkar, Mohit Khera   +5 more
doaj   +1 more source

A novel compound heterozigous mutation of the aromatase gene in an adult man

, 2006
Descriptions of a new case of human aromatase deficiency useful for a better understanding of male oestrogen ...
LUBERTO, Alessandra, Mirta Stivel, PIGNATTI, Elisa, Paula Antunez, ROCHIRA, Vincenzo, Evan R. Simpson, Antonio Balestrieri, Claudio Aranda, SIMONE, Maria Luisa, Laura Maffei, M. Stivel, CARANI, Cesare, Bibiana Fabre   +12 more
core  

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source