Results 11 to 20 of about 665,294 (217)
Cancer Management and Research, 2012 Jane Bryce1, Martina Bauer2, Peyman Hadji21National Cancer Institute, Naples, Italy; 2Philipps University of Marburg, Marburg, GermanyBackground: In order to reduce the risk of recurrence, adjuvant treatment with an aromatase inhibitor (AI) is ...
Bryce J, Bauer M, Hadji P
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Aromatase inhibitors in the treatment of breast cancer in post-menopausal female patients: an update
Breast Cancer: Targets and Therapy, 2011 Reva Schneider1, Ayman Barakat1, John Pippen1,2,3, Cynthia Osborne1,2,3 1Medical Oncology, Baylor-Sammons Cancer Center, 2Texas Oncology PA, 3US Oncology, Dallas, TX, USA Abstract: Estrogen and its metabolites play a significant role in the proliferation
Schneider RE +3 more
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Clinical utilities of aromatase inhibitors in breast cancer
International Journal of Women's Health, 2015 Saranya Chumsri Department of Hematology and Oncology, Mayo Clinic, Jacksonville, FL, USA Abstract: Aromatase is an enzyme that converts testosterones to estrogens.
Chumsri S
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Effect of anastrozole on bone mineral density and lipid profiles when used to prevent breast cancer in high risk postmenopausal women [PDF]
, 2012 PhDThe role of aromatase inhibitors (AIs) in breast cancer has expanded since their introduction in the mid-1990s. They are superior to tamoxifen in the treatment of postmenopausal women with oestrogen dependant tumours in the metastatic, neoadjuvant ...
Singh, Shalini
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Cloning, sequencing and In situ localisation of guppy brain aromatase, cyp19b
Oestrogens are biosynthesised by cytochrome p450-aromatase (Cyp19). Brain oestrogens serve several important functions of which nerve protection, cell proliferation, nerve development and behaviour control are a few.
Hallgren, Stefan, +1 more
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Gynecologic Oncology Reports, 2022 Therapeutic options for recurrent adult granulosa cell tumors (AGCT) are limited. After examining the hormonal pathways involved in FOXL2-mutated granulosa cell tumor development, a novel treatment regimen was utilized for recurrent AGCT: a combination ...
Rebekah M. Summey +7 more
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Dermatology and Therapy, 2020 Anastrozole is an aromatase inhibitor. Anastrozole competitively inhibits the aromatase enzyme, which synthesizes estrogen. It is used for estrogen receptor-positive breast cancers.
Yoo Jung Kim, Philip R. Cohen
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Virtual Screening for Identification of Dual Inhibitors against CDK4/6 and Aromatase Enzyme
Molecules, 2023 CDK4/6 and aromatase are prominent targets for breast cancer drug discovery and are involved in abnormal cell proliferation and growth. Although aromatase inhibitors have proven to be effective (for example exemestane, anastrozole, letrozole), resistance
Tenzin Adon +6 more
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Epitope characterization of an aromatase monoclonal antibody suitable for the assessment of intratumoral aromatase activity. [PDF]
PLoS ONE, 2009 Immunohistochemistry is one of the most suitable methods for the detection of intratumoral aromatase in order to identify patients who may respond to aromatase inhibitor therapy in hormone-dependent breast cancer.
Yanyan Hong +7 more
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Drug Design, Development and Therapy, 2014 Veda Prachayasittikul,1 Ratchanok Pingaew,2 Chanin Nantasenamat,3 Supaluk Prachayasittikul,3 Somsak Ruchirawat,4,5 Virapong Prachayasittikul1 1Department of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University ...
Prachayasittikul V +5 more
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