Results 11 to 20 of about 49,677 (283)
Arrestin/Clathrin Interaction [PDF]
Journal of Biological Chemistry, 1997 Jason G. Krupnick +3 more
+6 more sources
Deceptive beauty of non-natural structures. [PDF]
Protein SciAbstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Gurevich VV, Gurevich EV.
europepmc +2 more sources
Progressive reduction of its expression in rods reveals two pools of arrestin-1 in the outer segment with different roles in photoresponse recovery. [PDF]
PLoS ONE, 2011 Light-induced rhodopsin signaling is turned off with sub-second kinetics by rhodopsin phosphorylation followed by arrestin-1 binding. To test the availability of the arrestin-1 pool in dark-adapted outer segment (OS) for rhodopsin shutoff, we measured ...
Whitney M Cleghorn +7 more
doaj +1 more source
β-arrestin functionally regulates the non-bleaching pigment parapinopsin in lamprey pineal. [PDF]
PLoS ONE, 2011 The light response of vertebrate visual cells is achieved by light-sensing proteins such as opsin-based pigments as well as signal transduction proteins, including visual arrestin.
Emi Kawano-Yamashita +5 more
doaj +1 more source
Frontiers in Oncology, 2023 Hormones may be key factors driving cancer development, and epidemiological findings suggest that steroid hormones play a crucial role in ovarian tumorigenesis.
Ji-Won Ryu +12 more
doaj +1 more source
The arrestin superfamily: cone arrestins are a fourth family [PDF]
FEBS Letters, 1995 Arrestins constitute a superfamily of regulatory proteins that down‐regulate phosphorylated G‐protein membrane receptors, including rod and cone photoreceptors and adrenergic receptors. The potential role of arrestin in color visual processes led us to identify a cDNA encoding a cone‐like arrestin in Xenopus laevis, the principle amphibian biological ...
Craft, Cheryl M., Whitmore, Donald H.
openaire +2 more sources
Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth. [PDF]
PLoS ONE, 2014 β-arrestins, ubiquitous cellular scaffolding proteins that act as signaling mediators of numerous critical cellular pathways, are attractive therapeutic targets because they promote tumorigenesis in several tumor models.
Jonathan W Kotula +7 more
doaj +1 more source
Frontiers in Physiology, 2021 An increased vulnerability has been detected after ischemia/reperfusion injury in cardiomyocytes in diabetic patients. Glucagon-like peptide-1 (GLP-1) has been proven to have a notable cardioprotective effect in cardiomyocytes.
Xietian Pan, Chengxiang Li, Haokao Gao
doaj +1 more source
The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.
PLoS ONE, 2011 Arrestins are multifunctional signaling adaptors originally discovered as proteins that "arrest" G protein activation by G protein-coupled receptors (GPCRs).
Sergio Coffa +6 more
doaj +1 more source