Results 161 to 170 of about 9,354 (195)

Arrestin-substypes in insect antennae

Cellular Signalling, 1993
Arrestin is supposed to be involved in uncoupling receptor-mediated second messenger cascades. Clones encoding proteins homologous to arrestin have been isolated from antennal cDNA libraries of Locusta migratoria and Heliothis virescens. Based on the size and several characteristic motifs, the two proteins are considered as members of different ...
K, Raming, J, Freitag, J, Krieger, H, Breer   +3 more
openaire   +2 more sources

Permanently biased toward arrestins

Science Signaling, 2021
The seven-transmembrane receptors D6R and C5aR2 are natural examples of β-arrestin–biased receptors.
openaire   +2 more sources

Arrestins in Fungi

Science's STKE, 2005
Herranz et al . report the identification of a fungal arrestin homolog and its role in pH signaling. PalF, a protein containing C-terminal and N-terminal arrestin domains, interacted with PalH, the 7 transmembrane receptor (7TMR) in two-hybrid assays and glutathione- S -transferase (GST) pull-
openaire   +1 more source

Arrestin Regulation of Small GTPases

2013
The regulation of small GTPases by arrestins is a relatively new way by which arrestin can exert influence over cell signalling cascades, hence, molecular interactions and specific binding partners are still being discovered. A pathway showcasing the regulation of GTPase activity by β-arrestin was first elucidated in 2001.
Ryan T, Cameron, George S, Baillie
openaire   +2 more sources

Characterization of arrestin expression and function

2002
Publisher Summary Arrestins mediate the desensitization and trafficking of numerous G protein coupled receptors (GPCRs). Agonist-dependent phosphorylation of GPCRs by GPCR kinases (GRKs) promotes high-affinity binding of arrestins that in turn sterically inhibit G protein interaction with the agonist-activated GPCR. There are currently four mammalian
Stuart J, Mundell, Michael J, Orsini, Jeffrey L, Benovic   +2 more
openaire   +2 more sources

β-Arrestins as Important Regulators of Glucose and Energy Homeostasis

Annual Review of Physiology, 2022
Sai P Pydi, Jürgen Wess, Mario Rossi
exaly  

Key Metabolic Functions of β-Arrestins: Studies with Novel Mouse Models

Trends in Endocrinology and Metabolism, 2021
Sai P Pydi, Jürgen Wess, Luiz Felipe Barella   +2 more
exaly  

Splice Variants of Arrestins

Experimental Eye Research, 1996
K, Palczewski, W C, Smith
openaire   +2 more sources

Arrestins

2022
openaire   +1 more source

The Two β-Arrestins Regulate Distinct Metabolic Processes: Studies with Novel Mutant Mouse Models

International Journal of Molecular Sciences, 2022
Jürgen Wess
exaly