Results 161 to 170 of about 7,477 (214)

Multi-faceted roles of β-arrestins in G protein-coupled receptor endocytosis. [PDF]

Nat Commun
Liu J, Xue L, Ravier MA, Eshak F, Acher FC, Goupil-Lamy A, Cimadevila M, Drube J, Hoffmann C, Inoue A, Trinquet E, Dupuis E, Prézeau L, Pin JP, Rondard P.   +14 more
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Phosphoregulation of the novel hemi-arrestin MAPK scaffold Sms1 prevents untimely mating. [PDF]

Nat Commun
Sieber B, Merlini L, Li W, Besomi M, Michon L, Gordon-Lennox S, Martin SG.   +6 more
europepmc   +1 more source

β-arrestin 1 and integrin-linked kinase interact in epidermal keratinocytes and regulate cell motility. [PDF]

Tissue Barriers
Murphy-Marshman H, Ivanova IA, Bhattacharya M, Dagnino L.   +3 more
europepmc   +1 more source

The Role of Individual Residues in the N-Terminus of Arrestin-1 in Rhodopsin Binding. [PDF]

Int J Mol Sci
Vishnivetskiy SA, Paul T, Gurevich EV, Gurevich VV.   +3 more
europepmc   +1 more source

A genetically encoded nanobody sensor reveals conformational diversity in β-arrestins orchestrated by distinct seven transmembrane receptors. [PDF]

Proc Natl Acad Sci U S A
Sarma P, Nagy Marková V, Dalal A, Mishra S, Zaidi N, Tiwari D, Yadav MK, Roy N, Mahajan G, Miclea P, Lazar J, Shukla AK.   +11 more
europepmc   +1 more source

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Arrestins in Bone

2013
Parathyroid hormone (PTH) is the principle regulator of calcium-phosphorus metabolism and bone turnover. Because of its central role in bone remodeling, recombinant human PTH (i.e., Forteo®; PTH(1-34)) has been developed for the treatment of osteoporosis.
Brittany N, Bohinc, Diane, Gesty-Palmer
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Diversity in arrestin function

Cellular and Molecular Life Sciences, 2009
The termination of heptahelical receptor signaling is a multilevel process coordinated, in large part, by members of the arrestin family of proteins. Arrestin binding to agonist-occupied receptors promotes desensitization by interrupting receptor-G protein coupling, while simultaneously recruiting machinery for receptor endocytosis, vesicular ...
Ryan T, Kendall, Louis M, Luttrell
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Arrestins lie in wait

Science Signaling, 2023
Preassociation of β-arrestins with the plasma membrane facilitates their interactions with GPCRs.
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Phosphorylation-dependent conformational changes of arrestin in the rhodopsin–arrestin complex

Physical Chemistry Chemical Physics, 2020
Conformations of GPCR-bound arrestin depend on the phosphorylation patterns of the GPCR C-loop.
Dali Wang, Xiangdong Liu, Jianqiang Liu, Chen Song   +3 more
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The Role of Arrestins in Development

2013
β-Arrestins are versatile scaffolding proteins that are involved in orchestrating a large number of signaling cascades. Because β-arrestin 1 and β-arrestin 2 are individually dispensable during development, it has long been assumed that β-arrestins do not play an important role during embryogenesis.
Melanie, Philipp, Tama, Evron, Marc G, Caron   +2 more
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